Abstract: Imaging agents comprising an isolated polypeptide conjugated with a radionucleide and a chelator; wherein the isolated polypeptide binds specifically to HER2, or a variant thereof; and methods for preparing and using these imaging agents.

Abstract: The present invention describes a versatile, robust and environmentally controlled platform with a linear temperature gradient for massively parallel chemical or biochemical processing. This apparatus is capable of probing the phase transition behavior of macromolecules in solution, both thermodynamically and kinetically. This includes—but is not limited to—liquid/liquid phase transition behavior of antibody solutions and in situ gelation of thermo-responsive polymers. The device can be operated in a multiplex fashion using a controlled temperature gradient architecture and visualized by dark field microscopy or by other optical intensity measurements.

Abstract: The presently disclosed subject matter provides for antigen-recognizing receptors that specifically target uPAR and cells comprising such uPAR-targeted antigen-recognizing receptors. The presently disclosed subject matter further provides uses of the uPAR-targeted antigen-recognizing receptors for treatment.

Abstract: Herein disclosed are systems and methods related to delivery systems using solid source chemical fill vessels. The delivery system can include a vapor deposition reactor, two or more fill vessels, of which one of more can be remote from the vapor deposition reactor. Each fill vessel is configured to hold solid source chemical reactant therein. An interconnect line or conduit can fluidly connect the vapor deposition reactor with one or more of the fill vessels. A line heater can heat at least a portion of the interconnect line to at least a minimum line temperature.

Abstract: The disclosed technology relates to redox flow batteries (“RFB”), and particularly to electrolytes useful in RFBs based on 2,5-dimercapto-1,3,4-thiadiazole (“DMTD”) and derivatives thereof.

Abstract: The invention provides DNA compositions that relate to transgenic insect resistant maize plants. Also provided are assays for detecting the presence of the maize DAS-59122-7 event based on the DNA sequence of the recombinant construct inserted into the maize genome and the DNA sequences flanking the insertion site. Kits and conditions useful in conducting the assays are provided.

Abstract: Neural network-based categorization can be improved by incorporating graph neural networks that operate on a graph representing the taxonomy of the categories into which a given input is to be categorized by the neural network based-categorization. The output of a graph neural network, operating on a graph representing the taxonomy of categories, can be combined with the output of a neural network operating upon the input to be categorized, such as through an interaction of multidimensional output data, such as a dot product of output vectors. In such a manner, information conveying the explicit relationships between categories, as defined by the taxonomy, can be incorporated into the categorization. To recapture information, incorporate new information, or reemphasize information a second neural network can also operate upon the input to be categorized, with the output of such a second neural network being merged with the output of the interaction.

Abstract: Systems and methods of monitoring inventory of a product storage facility include an image capture device configured to move about the product storage areas of the product storage facility and capture images of the product storage areas from various angles. A computing device coupled to the image capture device obtains the images of the product storage areas captured by the image capture device and processes the obtained images of the product storage areas to detect individual products captured in the obtained images. Based on detection of the individual products captured in the images, the computing device analyzes each of the obtained images to detect one or more adjacent product storage structures (shelves, pallets, etc.) and identifies and selects a single image that fully shows a product storage structure of interest and fully shows each of the products stored on the product storage structure of interest.

Abstract: The present disclosure provides compounds which are immunomodulators and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.

Abstract: The disclosure relates to a table (100). The table (100) has a table top (102), a plurality of legs (104) connectable to the table top (102), and an air purifier (106) adapted to be placed below the table top (102). A bottom side of the table top (102) is provided with at least one groove (112) extending in a circumferential direction for preventing liquid from traveling from an outer edge of the table top (102) along the bottom side of the table top (102) and reaching an inner section of the air purifier (106). The disclosure also relates to a method for purifying air using a table (100).

Abstract: An electronic device can include a housing defining an aperture and a display positioned in the aperture. The display and the housing can define an internal volume in which a speaker assembly is positioned. The speaker assembly can include a speaker module and a speaker enclosure in fluid communication, with the speaker enclosure at least partially defining a speaker volume.

Abstract: Embodiments of a recombinant human Parainfluenza Virus (hPIV) F ectodomain trimer stabilized in a prefusion conformation are provided. Also disclosed are nucleic acids encoding the hPIV F ectodomain trimer and methods of producing the hPIV F ectodomain trimer. Methods for inducing an immune response in a subject are also disclosed. In some embodiments, the method can be a method for treating or inhibiting a hPIV infection in a subject by administering a effective amount of the recombinant hPIV F ectodomain trimer to the subject.

Abstract: Embodiments disclosed herein are directed to devices and methods for performing spatially-varying brightness correction of a flash image. The spatially-varying brightness correction utilizes a set of images that includes one or more images captured under flash illumination and one or more images captured without flash illumination, which are used to decompose one of the flash images or an image generated therefrom into a flash contribution image and an ambient contribution image. The flash contribution image and the ambient contribution image are recombined to generate a corrected flash image, and information about the flash module and/or scene is used to adjust the relative contributions of these images during recombination.

Abstract: The present disclosure is directed to compounds of Formula (1): wherein m, n, Y, R1, R2, R3, R4 and R5 are each as described herein, as stereoisomers, enantiomers or tautomers thereof or mixtures thereof; or pharmaceutically acceptable salts, solvates or prodrugs thereof, and pharmaceutical compositions comprising the compounds of Formula (I), as described herein, which are useful as voltage-gated potassium channel modulators and are therefore are useful in treating seizure disorders such as epilepsy.

Abstract: Coating compositions comprise: a curable compound comprising: a core chosen from a C6 carbocyclic aromatic ring, a C2-5 heterocyclic aromatic ring, a C9-30 fused carbocyclic aromatic ring system, a C4-30 fused heterocyclic aromatic ring system, C1-20 aliphatic, and C3-20 cycloaliphatic, and three or more substituents of formula (1) wherein at least two substituents of formula (1) are attached to the aromatic core; provided that no substituents of formula (1) are in an ortho position to each other on the same aromatic ring of the core; a polymer; and one or more solvents, wherein the total solvent content is from 50 to 99 wt % based on the coating composition.

Abstract: An electronic device display may have pixels formed from crystalline semiconductor light-emitting diode dies, organic light-emitting diodes, or other pixel structures. The pixels may be formed on a display panel substrate. A display panel may extend continuously across the display or multiple display panels may be tiled in two dimensions to cover a larger display area. Interconnect substrates may have outwardly facing contacts that are electrically shorted to corresponding inwardly facing contacts such as inwardly facing metal pillars associated with the display panels. The interconnect substrates may be supported by glass layers. Integrated circuits may be embedded in the display panels and/or in the interconnect substrates. A display may have an active area with pixels that includes non-spline pixels in a non-spline display portion located above a straight edge of the display and spline pixel in a spline display portion located above a curved edge of the display.

Abstract: A device for detecting gamma radiation has an assembly of scintillating and light-guiding materials, producing scintillation light upon incidence of radiation. At least one photon-detector device includes a detection surface optically coupled to the assembly. The assembly includes at least one photonic crystal slab configured to direct said scintillation light towards the detection surface along an extraction direction. The extraction direction is substantially perpendicular to the detection surface. The photonic crystal slab is arranged substantially perpendicular to the detection surface.

Abstract: A housing of a device comprises a screw boss that extends outwardly from a first base plate proximate to a corner of the housing. Additionally, the housing of the device includes a force dissipation member. The force dissipation member includes a central portion that is sized to detachably attach around the screw boss. The force dissipation member further includes at least two arms that extend outwardly from the central portion, wherein each arm of the at least two arms is attached to a different side of the two walls of the housing.

Abstract: The present invention provides a method for treating a used particulate filter, comprising: removing particulates from the particulate filter; and introducing simulated ash into inlet channels of the particulate filter after removing the particulates.

Abstract: A method includes forming an assembly of layers including an InP cap layer on an InGaAs absorption region layer, wherein the InGaAs layer is on an n-InP layer, and wherein an underlying substrate layer underlies the n-InP layer. The method includes removing a portion of the InP cap and n-InP layer by dry etching.