Abstract: In one aspect, a method for implementing a cloud-platform push for one or more known data breaches includes the step of, for each data breach of the one or more known data breaches, providing a functionality that maps one or more kill chains or Tactics, Techniques, and Procedures (TTPs) for a specified set of security dimensions. A step includes generating a security rule for each mapped kill chain or TTP based on the functionality that maps the one or more kill chains or Tactics, Techniques, and Procedures (TTPs) for a specified set of security dimensions. A step includes pushing the security rule to an enterprise so that the enterprise is aware of a vulnerability in the data breach. A step includes generating a customized posture for a Virtual private cloud (VPC) in the enterprise's cloud-based network. A step includes determining that the data breach can occur within the enterprise's cloud-based network.

Abstract: A semiconductive composite material comprising a non-polar organic polymer, a polar organic copolymer, and an electrical conducting effective amount of an ultra-low-wettability carbon black. Also a method of making the composite material; a crosslinked polyethylene product made by curing the composite material; manufactured articles comprising a shaped form of the inventive composite material or product; and methods of using the inventive composite material, product, or articles.

Abstract: There is provided a computer implemented method. The method provides a generation of a proof of existence data structures. The method comprising: (i) receiving a request comprising a data reveal path, the data reveal path referencing a node of interest within an input hierarchical data structure (ii) obtaining the input hierarchical data structure comprising an input root node and a plurality of input nodes, wherein each of the input nodes within the input hierarchical data structure have an associated value, and (iii) generating an output hierarchical data structure based on the data reveal path and the input hierarchical data structure, wherein the output hierarchical data structure comprises a plurality of output nodes. There is also provided a method for verification of the proof of existence.

Abstract: A computer-implemented method for tracking, on a blockchain, at least two clients interacting with an asset, wherein the blockchain comprises a set of transactions associated with the asset, and a set of transactions associated with each client. The asset tracking comprising receiving an asset interaction event request comprising data based on at least two clients associated with an asset interaction event and data indicative of the asset, generating an event transaction based on a reference to the set of transactions associated with the asset and references to the sets of transactions associated with the at least two clients, and submitting the event transaction to the blockchain.

Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.

Abstract: The present disclosure generally relates to engaging in cross device interactions. The method includes at a first device with a first display, while a second device having a second display is placed over a first region of the first display, detecting, via input devices of the first device, a first input. In response to detecting the first input and in accordance with a determination that the first input occurred while focus was directed to the second device, the method includes causing a response to the first input to be displayed on the second display. In response to detecting the first input and in accordance with a determination that the first input occurred while focus was directed to the first device, the method includes displaying, on the first display, a response to the first input without causing a response to the first input to be displayed on the second display.

Abstract: Embodiments of a recombinant Respiratory Syncytial Virus (RSV) F ectodomain trimer stabilized in a prefusion conformation are provided. Also disclosed are nucleic acids encoding the RSV F ectodomain trimer and methods of producing the RSV F ectodomain trimer. Methods for inducing an immune response in a subject are also disclosed. In some embodiments, the method can be a method for treating or preventing a RSV infection in a subject by administering a therapeutically effective amount of the recombinant RSV F ectodomain trimer to the subject.

Abstract: Systems and methods for managing graphic design using metadata relationships are described. According to certain aspects, an electronic device may display a visual design including a set of design elements, each of which may be contained within a corresponding container. The electronic device may receive a selection to spatially adjust a design element, and may determine a modification to the design element based an element behavior of the design element and/or a container behavior of the corresponding container. The electronic device may display, in the user interface, the design element reflecting the modification.

Abstract: The composition inhibits severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) via competitive binding to SARS-COV-2 spike protein. The composition includes a plurality of sulfated glycosaminoglycans which bind to SARS-COV-2 spike protein, preventing binding to and uptake by host cells. The sulfated glycosaminoglycans, including N-, 2-O, 3-O, or 6-O sulfate groups, or combinations thereof, include heparins and fucoidans, such as those isolated from brown seaweed. The compositions show antiviral activity, with EC50 as low as 0.08 ?M, and low cytotoxicity, making it promising for clinical use. While established SARS-COV-2 treatments such as remdesivir need to be administered intravenously, the compositions discussed herein are advantageously capable to being delivered as a nasal spray, metered dose inhaler, oral delivery, etc.

Abstract: A moisture curable adhesive composition including at least 65 wt.-% of at least one isocyanate-functional polyurethane polymer P obtained by reacting: (a) a polyol composition including (a1) at least one polyester polyol PO1, (a2) at least one polyether polyol PO2, and (b) at least one polyisocyanate PI, wherein the adhesive composition further includes at least one non-functionalized thermoplastic polymer TP having a softening point determined by Ring and Ball method according to ISO 4625 standard of 70-200° C., preferably 75-185° C. The adhesive composition can also be used for bonding of substrates in production of white goods, automotive vehicles, and electronic devices.

Abstract: Integrated circuit structures having deep via bar width tuning are described. For example, an integrated circuit structure includes a plurality of gate lines extending over first and second semiconductor nanowire stack channel structures or fin structures. A plurality of trench contacts is intervening with the plurality of gate lines. A conductive structure is between the first and second semiconductor nanowire stack channel structures or fin structures, the conductive structure having a first width in a first region and a second width in a second region between the first and second semiconductor nanowire stack channel structures or fin structures, the second width different than the first width.

Abstract: Multiple voltage threshold integrated circuit structures with local layout effect tuning, and methods of fabricating multiple voltage threshold integrated circuit structures with local layout effect tuning, are described. For example, an integrated circuit structure includes a first fin structure or vertical arrangement of horizontal nanowires. A second fin structure or vertical arrangement of horizontal nanowires is laterally spaced apart from the first fin structure or vertical arrangement of horizontal nanowires. An N-type gate structure is over the first fin structure or vertical arrangement of horizontal nanowires. A P-type gate structure is over the second fin structure or vertical arrangement of horizontal nanowires, the P-type gate structure in contact with the N-type gate structure with a PN boundary between the P-type gate structure and the N-type gate structure.

Abstract: The present disclosure is directed toward systems, methods, and non-transitory computer-readable media for determining for a folder a file organization score and providing a free flow element based on the file organization score selectable to transition from providing a folder view to providing a free flow view. In some embodiments, the disclosed systems determine the file organization score indicating file organizational patterns associated with content items within the folder. Furthermore, based on receiving an indication of a selection of the free flow element, the disclosed systems transition from providing the folder view of the folder to providing the free flow view depicting graphical representations of the content items. Moreover, the graphical representations of the content items are arranged according to one or more content features associated with the content items.

Abstract: The invention provides a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, especially KRAS G12C inhibitors. The present invention provides a direct enantioselective chemical manufacturing method of making Compound A, or a pharmaceutically acceptable hydrate or solvent thereof: (I). The invention provides a process for preparing Intermediate B6* comprising reacting Intermediate B4* with Intermediate B5* in an atroposelective coupling reaction, using a chiral catalyst.

Abstract: Integrated circuit structures having reduced local layout effects, and methods of fabricating integrated circuit structures having reduced local layout effects, are described. For example, an integrated circuit structure includes an NMOS region including a first plurality of fin structures or vertical stacks of horizontal nanowires, and first alternating gate lines and trench contact structures over the first plurality of fin structures or vertical stacks of horizontal nanowires. The integrated circuit structure also includes a PMOS region including a second plurality of fin structures or vertical stacks of horizontal nanowires, and second alternating gate and trench contact structures over the second plurality of fin structures or vertical stacks of horizontal nanowires. A gate line is shared between the NMOS region and the PMOS region, and a trench contact structure is shared between the NMOS region and the PMOS region.

Abstract: A nested shell enclosure covering behind the cab gaseous fuel tanks on a three dimensional structure. The method and system provides a releasable enclosure around the structure or a rack or the like formed by attaching a plurality of shell components which nest in a sequential pattern over the structure via housing latch assemblies formed on the interior wall surface of shell components to catch bracket assemblies attached to the structure and wherein the latch and catch assemblies releasably affix the enclosure shells to the structure and together without the use of threaded fasteners; and, wherein the shells components are nested and evenly disperse force along the perimeter edges where the shells overlap.

Abstract: Pharmaceutical compositions of the invention comprise EBNA1 inhibitors useful for the treatment of diseases caused by EBNA1 activity such as cancer, infectious mononucleosis, chronic fatigue syndrome, multiple sclerosis, systemic lupus erythematosus and rheumatoid arthritis. Pharmaceutical compositions of the invention also comprise EBNA1 inhibitors useful for the treatment of diseases caused by latent Epstein-Barr Virus (EBV) infection. Pharmaceutical compositions of the invention also comprise EBNA1 inhibitors useful for the treatment of diseases caused by lytic Epstein-Barr Virus (EBV) infection.

Abstract: The composition inhibits severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) via competitive binding to SARS-CoV-2 spike protein. The composition includes a plurality of sulfated glycosaminoglycans which bind to SARS-CoV-2 spike protein, preventing binding to and uptake by host cells. The sulfated glycosaminoglycans, including N-, 2-O, 3-O, or 6-O sulfate groups, or combinations thereof, include heparins and fucoidans, such as those isolated from brown seaweed. The compositions show antiviral activity, with EC50 as low as 0.08 ?M, and low cytotoxicity, making it promising for clinical use. While established SARS-CoV-2 treatments such as remdesivir need to be administered intravenously, the compositions discussed herein are advantageously capable to being delivered as a nasal spray, metered dose inhaler, oral delivery, etc.

Abstract: A battery cell having a cell casing in which a number of electrodes are arranged. The cell casing has an opening that is is covered by a gas-permeable membrane. An exterior of the membrane is covered by a cover element in order to restrict the ingress of matter into the cell casing.

Abstract: A battery cell having a cell casing in which a number of electrodes are arranged. The cell casing has a rupture region. The rupture region having an opening. The opening being covered by a gas-permeable membrane.