Patents by Inventor Paula Jeronimo

Paula Jeronimo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Processes for preparing medicaments for the treatment of cardiovascular diseases and intermediates for use therein
    Patent number: 10329268
    Abstract: The present invention provides a compound of formula N wherein: X is CH2, oxygen or sulphur; R1, R2 and R3 are the same or different and signify hydrogens, halogens, alkyl, alkyloxy, hydroxy, nitro, alkylcarbonylamino, alkylamino or dialkylamino group, wherein N is in the form of the individual R- and S-enantiomer or a mixture of the (R)- and (S)-enantiomer. The present invention also provides a compound of formula MA. The present invention also provides processes for preparing the above compounds, and processes involving their use. The compounds are particularly useful as intermediates in the synthesis of peripherally-selective inhibitors of dopamine-?-hydroxylase.
    Type: Grant
    Filed: September 12, 2014
    Date of Patent: June 25, 2019
    Assignee: Bial-Portela & CA, S.A.
    Inventors: Domenico Russo, Jorge Wahnon, William Maton, Beat T. Weber, Paula Jeronimo, Luisa Sousa, Pedro Barrocas, Rita Pires, Ricardo Lima, Teofilo Vasconcelos
  • Processes for Preparing Medicaments for the Treatment of Cardiovascular Diseases and Intermediates for Use Therein
    Publication number: 20160221981
    Abstract: The present invention provides a compound of formula N wherein: X is CH2, oxygen or sulphur; R1, R2 and R3 are the same or different and signify hydrogens, halogens, alkyl, alkyloxy, hydroxy, nitro, alkylcarbonylamino, alkylamino or dialkylamino group, wherein N is in the form of the individual R- and S-enantiomer or a mixture of the (R)- and (S)-enantiomer. The present invention also provides a compound of formula MA. The present invention also provides processes for preparing the above compounds, and processes involving their use. The compounds are particularly useful as intermediates in the synthesis of peripherally-selective inhibitors of dopamine-?-hydroxylase.
    Type: Application
    Filed: September 12, 2014
    Publication date: August 4, 2016
    Inventors: Domenico RUSSO, Jorge WAHNON, William MATON, Beat T. WEBER, Paula JERÓNIMO, Luísa SOUSA, Pedro BARROCAS, Rita PIRES, Ricardo LIMA, Teófilo VASCONCELOS