Patents by Inventor Paula M. Pitha-Rowe

Paula M. Pitha-Rowe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF INHIBITING VIRAL REPLICATION
    Publication number: 20110269229
    Abstract: The instant invention provides methods for the treatment and prevention of viral infection, e.g., HIV infection, based on the discovery that viral replication utilizes the ubiquitination pathway of the host cell to replicate. Specifically, the invention provides methods for the treatment and prevention of viral infection, e.g., HIV infection, by modulation of ISG15 conjugation and deconjugation, e.g., by modulation of the activity or expression of UBP43 or UBEL-1.
    Type: Application
    Filed: April 13, 2011
    Publication date: November 3, 2011
    Applicant: The Johns Hopkins University
    Inventors: Paula M. Pitha-Rowe, Atsushi Okumura, Myriam S. Kunzi
  • Ubiquitin-like protein isg15 for hiv inhibition
    Publication number: 20090136479
    Abstract: The instant invention provides methods for the treatment and prevention of viral infection, e.g., HIV infection, based on the discovery that viral replication utilizes the ubiquitination pathway of the host cell to replicate. Specifically, the invention provides methods for the treatment and prevention of viral infection, e.g., HIV infection, by modulation of ISG15 conjugation and deconjugation, e.g., by modulation of the activity or expression of UBP43 or UBEL-1.
    Type: Application
    Filed: June 28, 2005
    Publication date: May 28, 2009
    Applicant: The Johns Hopkins University
    Inventors: Paula M. Pitha-Rowe, Atsushi Okumura, Myriam S. Kunzi