Patents by Inventor Paula Macedo

Paula Macedo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of glutathione synthesis stimulating compounds in reducing insulin resistance
    Patent number: 7622447
    Abstract: There is provided a method of reducing insulin resistance in a mammalian patient comprising selecting a patient suffering from insulin resistance and administering a compound which increases hepatic glutathione and a compound which increases hepatic nitric oxide.
    Type: Grant
    Filed: January 27, 2003
    Date of Patent: November 24, 2009
    Assignee: DiaMedica Inc.
    Inventors: W. Wayne Lautt, Paula Macedo
  • Use of glutathione synthesis stimulating compounds in reducing insulin resistance
    Publication number: 20050124552
    Abstract: There is provided a method of reducing insulin resistance in a mammalian patient comprising selecting a patient suffering from insulin resistance and administering a compound which increases hepatic glutathione and a compound which increases hepatic nitric oxide.
    Type: Application
    Filed: January 27, 2003
    Publication date: June 9, 2005
    Inventors: W Lautt, Paula Macedo
  • Use of phosphodiesterase antagonists to treat insulin resistance
    Publication number: 20050119272
    Abstract: There is provided the use of a phosphodiesterase antagonist to reduce insulin resistance, and to amplify the effect of nitric oxide on skeletal muscle insulin-mediated glucose uptake in a mammal. In some instances, the antagonist is targeted to the liver. In some instances, the insulin resistance is hepatic insulin sensitizing substance (“HISS”) dependant insulin resistance.
    Type: Application
    Filed: January 27, 2003
    Publication date: June 2, 2005
    Applicant: DiaMedica Inc.
    Inventors: W. Lautt, Paula Macedo
  • Use of phosphodiesterase antagonists to treat insulin resistance
    Publication number: 20030181461
    Abstract: A phosphodiesterase antagonist is used to reduce insulin resistance, and to amplify the effect of nitric oxide on skeletal muscle insulin-mediated glucose uptake in a mammal. In some instances, the antagonist is targeted to the liver. In some instances, the insulin resistance is hepatic insulin sensitizing substance (“HISS”) dependant insulin resistance.
    Type: Application
    Filed: January 24, 2003
    Publication date: September 25, 2003
    Inventors: Wilfred Wayne Lautt, Paula Macedo