Patents by Inventor Paula N Belloni

Paula N Belloni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods, compositions and modes of delivery for the treatment of emphysema using 13-cis-retinoic acid
    Patent number: 6794416
    Abstract: The current invention is directed to methods of treating or preventing emphysema, pharmaceutical compositions suitable for the treatment or prevention of emphysema and methods for delivering formulations into the lung of a mammal suffering from emphysema. More generally, the invention encompasses the use of 13-cis-retinoic acid to treat or prevent certain chronic obstructive airway disorders, particularly chronic obstructive pulmonary disease including chronic bronchitis, emphysema and asthma in mammals, especially humans that smoke or smoked cigarettes. In another aspect, the present invention encompasses the use of pharmaceutical compositions of 13-cis-retinoic acid to treat emphysema. Moreover, the current invention encompasses the use of electrohydrodynamic aerosol devices, aerosol devices and nebulizers to deliver formulations of 13-cis-retinoic acid into the lung of a mammal suffering from emphysema. The invention also encompasses the systemic use as well as the local use of 13-cis-retinoic acid.
    Type: Grant
    Filed: September 26, 2001
    Date of Patent: September 21, 2004
    Assignee: Syntex (U.S.A.) LLC
    Inventor: Paula N Belloni
  • Methods, compositions and modes of delivery for the treatment of emphysema using 13-cis-retinoic acid
    Publication number: 20020049252
    Abstract: The current invention is directed to methods of treating or preventing emphysema, pharmaceutical compositions suitable for the treatment or prevention of emphysema and methods for delivering formulations into the lung of a mammal suffering from emphysema.
    Type: Application
    Filed: September 26, 2001
    Publication date: April 25, 2002
    Applicant: Syntex (U.S.A) LLC
    Inventor: Paula N. Belloni
  • Methods for treatment of Emphysema using 13-cis retinoic acid
    Patent number: 6339107
    Abstract: The current invention is directed to methods of treating or preventing emphysema, pharmaceutical compositions suitable for the treatment or prevention of emphysema and methods for delivering formulations into the lung of a mammal suffering from emphysema. More generally, the invention encompasses the use of 13-cis-retinoic acid to treat or prevent certain chronic obstructive airway disorders, particularly chronic obstructive pulmonary disease including chronic bronchitis, emphysema and asthma in mammals, especially humans that smoke or smoked cigarettes. In another aspect, the present invention encompasses the use of pharmaceutical compositions of 13-cis-retinoic acid to treat emphysema. Moreover, the current invention encompasses the use of electrohydrodynamic aerosol devices, aerosol devices and nebulizers to deliver formulations of 13-cis-retinoic acid into the lung of a mammal suffering from emphysema. The invention also encompasses the systemic use as well as the local use of 13-cis-retinoic acid.
    Type: Grant
    Filed: August 2, 2000
    Date of Patent: January 15, 2002
    Assignee: Syntex (U.S.A.) LLC
    Inventor: Paula N Belloni
  • Cationic lipids for gene therapy
    Patent number: 6034137
    Abstract: This invention provides novel cationic lipids, particularly guanidino lipids, and methods for their preparation. Also provided are polyanionic-lipid complexes comprising the lipids of the invention, their preparation and use to deliver biologically active substances, particularly nucleic acids to cells.
    Type: Grant
    Filed: October 20, 1997
    Date of Patent: March 7, 2000
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: Paula N. Belloni, Donald R. Hirschfeld, John O. Link, John J. Nestor, Jr., Gary A. Peltz