Patents by Inventor Paula Ofek

Paula Ofek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds suited as nanocarriers for active agents and their use
    Patent number: 9682098
    Abstract: The invention relates to a compound suited as entity carrier, having the general formula (I) wherein X is an amine-containing residue further defined herein. The invention further relates to the use of such compounds, a nanocarrier system, a kit comprising such compounds and methods for gene silencing and anti-cancer treatment.
    Type: Grant
    Filed: July 20, 2015
    Date of Patent: June 20, 2017
    Assignees: Ramot at Tel-Aviv University Ltd., Freie Universitaet Berlin
    Inventors: Rainer Haag, Wiebke Fischer, Abdul Mohiuddin Quadir, Ronit Satchi-Fainaro, Paula Ofek
  • NANOCARRIER SYSTEM FOR MICRORNAS AND USES THEREOF
    Publication number: 20160145628
    Abstract: Described herein are novel polyglycerol-amine polymeric nanocarriers in complex with microRNAs and their uses in the treatment of cancer, in particular glioblastoma. Delivery of the polymeric nanocarriers in complex with microRNAs in cell lines and in vivo inhibited cell proliferation, cell cycle progression, cell migration and tumor growth.
    Type: Application
    Filed: June 18, 2014
    Publication date: May 26, 2016
    Inventors: Noga Yerushalmi, Sharon Kredo-Russo, Gila Lithwick Yanai, Ronit Satchi-Fainaro, Paula Ofek
  • COMPOUNDS SUITED AS NANOCARRIERS FOR ACTIVE AGENTS AND THEIR USE
    Publication number: 20150320786
    Abstract: The invention relates to a compound suited as entity carrier, having the general formula (I) wherein X is an amine-containing residue further defined herein. The invention further relates to the use of such compounds, a nanocarrier system, a kit comprising such compounds and methods for gene silencing and anti-cancer treatment.
    Type: Application
    Filed: July 20, 2015
    Publication date: November 12, 2015
    Applicants: FREIE UNIVERSITAET BERLIN, RAMOT AT TEL-AVIV UNIVERSITY LTD.
    Inventors: Rainer HAAG, Wiebke FISCHER, Abdul Mohiuddin QUADIR, Ronit SATCHI-FAINARO, Paula OFEK
  • Compounds suited as nanocarriers for active agents and their use
    Patent number: 9102595
    Abstract: The invention relates to a compound suited as entity carrier, having the general formula (I) wherein X is an amine-containing residue further defined herein. The invention further relates to the use of such compounds, a nanocarrier system, a kit comprising such compounds and methods for gene silencing and anti-cancer treatment.
    Type: Grant
    Filed: May 22, 2009
    Date of Patent: August 11, 2015
    Assignees: Ramot at Tel-Aviv University Ltd., Freie Universitaet Berlin
    Inventors: Rainer Haag, Wiebke Fischer, Mohiuddin Abdul Quadir, Ronit Satchi-Fainaro, Paula Ofek
  • COMPOUNDS SUITED AS NANOCARRIERS FOR ACTIVE AGENTS AND THEIR USE
    Publication number: 20110082090
    Abstract: The invention relates to a compound suited as entity carrier, having the general formula (I) wherein X is an amine-containing residue further defined herein. The invention further relates to the use of such compounds, a nanocarrier system, a kit comprising such compounds and methods for gene silencing and anti-cancer treatment.
    Type: Application
    Filed: May 22, 2009
    Publication date: April 7, 2011
    Applicants: Ramot at Tel-Aviv University Ltd., Freie Universitat Berlin
    Inventors: Rainer Haag, Wiebke Fischer, Mohiuddin Abdul Quadir, Paula Ofek