Patents by Inventor Paula T. Hammond Cunningham
Paula T. Hammond Cunningham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230406905Abstract: An injectable nanoparticular formulation and method of use thereof for treating non-compressible hemorrhage or internal bleeding has been developed. The formulation includes two interactive components, one a targeting nanoparticle with a polypeptide sequence that binds to a cell present at a site of injury, and the other a crosslinking nanoparticle with a bioorthogonal click-crosslinking group.Type: ApplicationFiled: February 15, 2023Publication date: December 21, 2023Inventors: Paula T. Hammond Cunningham, Bradley D. Olsen, George Velmahos, Celestine Jia Huey Hong
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Patent number: 11230708Abstract: The present invention relates to concatemeric RNA molecules, compositions, particles, and methods of uses thereof.Type: GrantFiled: December 16, 2016Date of Patent: January 25, 2022Assignee: Massachusetts Institute of TechnologyInventors: Paula T. Hammond Cunningham, Connie Wu, Kevin E. Shopsowitz
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Patent number: 10074839Abstract: Battery separators for lithium-air batteries are provided. In some embodiments, a lithium-air battery may comprise one or more electrochemical cells including an anode, a cathode, an electrolyte, and a battery separator positioned between the anode and the cathode. The battery separator may comprise a porous membrane having a lithium ion conductive film on at least a portion of the porous membrane. The lithium ion conductive film may comprise layers designed to impart beneficial properties to the porous membrane and/or battery, such as resistance to dendrite formation, while having relatively minimal or no adverse effects on one or more important properties of the porous membrane (e.g., ionic conductivity, electrolyte permeability, weight, mechanical stability) and/or the overall battery.Type: GrantFiled: July 26, 2016Date of Patent: September 11, 2018Assignee: Massachusetts Institute of TechnologyInventors: Paula T. Hammond-Cunningham, Sun Hwa Lee
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Publication number: 20180034031Abstract: Battery separators for lithium-air batteries are provided. In some embodiments, a lithium-air battery may comprise one or more electrochemical cells including an anode, a cathode, an electrolyte, and a battery separator positioned between the anode and the cathode. The battery separator may comprise a porous membrane having a lithium ion conductive film on at least a portion of the porous membrane. The lithium ion conductive film may comprise layers designed to impart beneficial properties to the porous membrane and/or battery, such as resistance to dendrite formation, while having relatively minimal or no adverse effects on one or more important properties of the porous membrane (e.g., ionic conductivity, electrolyte permeability, weight, mechanical stability) and/or the overall battery.Type: ApplicationFiled: July 26, 2016Publication date: February 1, 2018Applicant: Massachusetts Institute of TechnologyInventors: Paula T. Hammond-Cunningham, Sun Hwa Lee
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Patent number: 9590278Abstract: An efficient perovskite solar cells can be synthesized from used car batteries by using both the anodes and cathodes of car batteries as material sources for the synthesis of lead iodide perovskite materials.Type: GrantFiled: August 6, 2015Date of Patent: March 7, 2017Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventors: Angela M. Belcher, Po-Yen Chen, Paula T. Hammond-Cunningham, Jifa Qi
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Patent number: 9274108Abstract: The invention is directed toward systems and methods for the formation of two dimensional monolayer structures of ordered biomacromolecules, such as viruses, atop cohesive polyelectrolyte multilayers to create functional thin films. Methods for the formation of such thin films are disclosed that involve an interdiffusion-induced assembly process of the biomacromolecules. The inventive systems provide a general platform for the systematic incorporation and assembly of organic, biological and inorganic materials and will enable many potential technological applications such as, for example, chemical and biological sensors, power devices and catalytic membranes.Type: GrantFiled: February 6, 2007Date of Patent: March 1, 2016Assignee: Massachusetts Institute of TechnologyInventors: Pil J. Yoo, Ki Tae Nam, Jifa Qi, Soo-Kwan Lee, Juhyun Park, Angela M. Belcher, Paula T. Hammond-Cunningham
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Publication number: 20160043449Abstract: An efficient perovskite solar cells can be synthesized from used car batteries by using both the anodes and cathodes of car batteries as material sources for the synthesis of lead iodide perovskite materials.Type: ApplicationFiled: August 6, 2015Publication date: February 11, 2016Inventors: Angela M. BELCHER, Po-Yen CHEN, Paula T. HAMMOND-CUNNINGHAM, Jifa QI
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Patent number: 9198875Abstract: A decomposable thin film includes a plurality of multilayer units including a first layer having a first charge and a second layer having a second charge, wherein at least a portion of the multilayers includes a polymeric cyclodextrin associated with a bioactive agent, wherein decomposition of the thin film is characterized by sequential removal of at least a portion of the layers having the first charge and degradation of layers having the second charge and by release of the bioactive agent from a corresponding layers; wherein the decomposable thin film including at least one degradable polyelectrolyte layer that is hydrolyzable.Type: GrantFiled: August 17, 2009Date of Patent: December 1, 2015Assignee: Massachusetts Institute of TechnologyInventors: Renee Chivon Smith, Paula T. Hammond-Cunningham
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Patent number: 8105652Abstract: A decomposable thin film comprising a plurality of polyelectrolyte layers of alternating charge, wherein decomposition of the thin film is characterized by degradation of at least a portion of the polyelectrolyte layers.Type: GrantFiled: July 26, 2006Date of Patent: January 31, 2012Assignee: Massachusetts Institute of TechnologyInventors: Kris C. Wood, Helen F. Chuang, Robert D. Batten, David M. Lynn, Paula T. Hammond Cunningham
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Patent number: 8075951Abstract: One aspect of the invention provides ion-exchange and gas-diffusion membranes, fabricated by a layer-by-layer approach, for use, e.g., in electrochemical cells; a process for making membrane electrode assemblies fabricated using porous frameworks, LBL composite membranes and LBL carbon-Polymer electrodes; and the application of the membrane and electrode assemblies to a variety of devices, both electrochemical and otherwise.Type: GrantFiled: April 30, 2009Date of Patent: December 13, 2011Assignee: Massachusetts Institute of TechnologyInventors: Paula T. Hammond-Cunningham, Tarek R. Farhat
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Publication number: 20110114244Abstract: The invention is directed toward systems and methods for the formation of two dimensional monolayer structures of ordered biomacromolecules, such as viruses, atop cohesive polyelectrolyte multilayers to create functional thin films. Methods for the formation of such thin films are disclosed that involve an interdiffusion-induced assembly process of the biomacromolecules. The inventive systems provide a general platform for the systematic incorporation and assembly of organic, biological and inorganic materials and will enable many potential technological applications such as, for example, chemical and biological sensors, power devices and catalytic membranes.Type: ApplicationFiled: February 6, 2007Publication date: May 19, 2011Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventors: Pil J. Yoo, Ki Tae Nam, Jifa Qi, Soo-Kwan Lee, Juhyun Park, Angela M. Belcher, Paula T. Hammond-Cunningham
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Publication number: 20110064936Abstract: One aspect of the invention relates to a method for installing coatings of different morphology and function within a single textile membrane. Remarkably, the methods described herein enable one to engineer the properties of a material at the nanoscopic level and produce the material in commercially viable quantities. For example, by simply controlling the flow rate of charged species passing through an electrospun material during spray-assisted Layer-by-Layer (Spray-LbL) deposition, individual fibers within the matrix can be conformally functionalized for ultra-high surface area catalysis, or bridged to form a networked sublayer with complimentary properties.Type: ApplicationFiled: September 17, 2009Publication date: March 17, 2011Applicant: Massachusetts Institute of TechnologyInventors: Paula T. Hammond-Cunningham, Kevin C. Krogman, Joseph L. Lowery, Gregory C. Rutledge
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Publication number: 20100159366Abstract: The embodiments described herein relate generally to methods, compositions, articles, and devices associated with layer-by-layer assembly and/or functionalization of carbon-based nanostructures and related structures. In some embodiments, the present invention provides methods for forming an assembly of carbon-based nanostructures on a surface. The carbon-based nanostructure assembly may exhibit enhanced properties, such as improved arrangement of carbon-based nanostructures (e.g., carbon nanotubes) and/or enhanced electronic and/or ionic conductivity and/or other useful features. In some cases, improved properties may be observed due to the attachment of functional groups to the surfaces of carbon-based nanostructures. Using methods described herein, formation of carbon-based nanostructure assemblies may be controlled to produce structures with enhanced properties.Type: ApplicationFiled: August 14, 2009Publication date: June 24, 2010Applicant: Massachusetts Institute of TechnologyInventors: Yang Shao-Horn, Seung Woo Lee, Naoaki Yabuuchi, Paula T. Hammond-Cunningham
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Publication number: 20100040674Abstract: A decomposable thin film includes a plurality of multilayer units including a first layer having a first charge and a second layer having a second charge, wherein at least a portion of the multilayers includes a polymeric cyclodextrin associated with a bioactive agent, wherein decomposition of the thin film is characterized by sequential removal of at least a portion of the layers having the first charge and degradation of layers having the second charge and by release of the bioactive agent from a corresponding layers; wherein the decomposable thin film including at least one degradable polyelectrolyte layer that is hydrolyzable.Type: ApplicationFiled: August 17, 2009Publication date: February 18, 2010Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventors: Renee Chivon Smith, Paula T. Hammond-Cunningham
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Publication number: 20090269491Abstract: One aspect of the invention provides ion-exchange and gas-diffusion membranes, fabricated by a layer-by-layer approach, for use, e.g., in electrochemical cells; a process for making membrane electrode assemblies fabricated using porous frameworks, LBL composite membranes and LBL carbon-Polymer electrodes; and the application of the membrane and electrode assemblies to a variety of devices, both electrochemical and otherwise.Type: ApplicationFiled: April 30, 2009Publication date: October 29, 2009Applicant: Massachusetts Institute of TechnologyInventors: Paula T. Hammond-Cunningham, Tarek R. Farhat
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Publication number: 20090258045Abstract: A structure includes a substrate and a first plurality of bilayers on the substrate. The first plurality of bilayers includes a first layer including an antimicrobial peptide having a charge, and a second layer including a polyelectrolyte having a charge opposite the charge of the first layer. At least a portion of the structure is capable of degrading by sequential removal of the first layer and the second layer, and releasing the antimicrobial peptide from the structure.Type: ApplicationFiled: March 18, 2009Publication date: October 15, 2009Applicant: Massachusetts Institute of TechnologyInventors: Helen F. Chuang, Anita Shukla, Christopher R. Loose, Paula T. Hammond-Cunningham, Gregory Stephanopoulos
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Patent number: 7220452Abstract: One aspect of the present invention relates to a method for transferring a patterned polyelectrolyte multilayer from a first surface, e.g., a PDMS stamp, to a second surface, e.g. fabric or a non-woven material, wherein the patterned polyelectrolyte multilayer on the first surface is brought into contact with the second surface in order to transfer the polyelectrolyte multilayer from the first surface to the second surface. Another aspect of the present invention relates to a stamp comprising a surface coated with a polyelectrolyte multilayer suitable for transfer to a substrate using the aforementioned method of transferring patterned multilayers.Type: GrantFiled: May 18, 2003Date of Patent: May 22, 2007Assignee: Massachusetts Institute of TechnologyInventors: Paula T. Hammond Cunningham, Juhyun Park
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Publication number: 20040086709Abstract: One aspect of the present invention relates to a method for transferring a patterned polyelectrolyte multilayer from a first surface, e.g., a PDMS stamp, to a second surface, e.g. fabric or a non-woven material. Another aspect of the present invention relates to a stamp comprising a surface coated with a polyelectrolyte multilayer suitable for transfer to a substrate using the aforementioned method of transferring patterned multilayers.Type: ApplicationFiled: May 18, 2003Publication date: May 6, 2004Inventors: Paula T. Hammond Cunningham, Juhyun Park