Patents by Inventor Pauli Kallio

Pauli Kallio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for increasing production of erythromycin
    Patent number: 5908764
    Abstract: Methods and compositions for increasing the production of erythromycins are provided. In particular, the invention relates to the engineering of erythromycin-producing organisms to express a heterologous oxygen-binding protein.
    Type: Grant
    Filed: May 22, 1997
    Date of Patent: June 1, 1999
    Assignee: Solidago AG
    Inventors: Peter Brunker, Wolfgang Minas, Pauli Kallio, James E. Bailey
  • Cross-regulation of gene expression in recombinant cells
    Patent number: 5416008
    Abstract: Recombinant cells providing for the controlled expression of product proteins by way of cross-regulation between interacting operons. A structural gene for a product protein and a structural gene for a repressor of a second operon are included in a first operon. A protein encoded by a structural gene of the second operon is a repressor of the first operon. The second operon may reside on a plasmid or a chromosome of the host cell. The present invention provides for controlled expression of product protein over a range of copy numbers, as well as high transcription efficiency in the induced state. The invention includes methods for the controlled expression of product protein by recombinant cells.
    Type: Grant
    Filed: October 1, 1991
    Date of Patent: May 16, 1995
    Assignee: California Institute of Technology
    Inventors: James E. Bailey, Wilfred Chen, Pauli Kallio