Patents by Inventor Pauline BERTHOLET

Pauline BERTHOLET has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Matrix in ball form as a cell carrier
    Patent number: 10507231
    Abstract: The invention relates to a matrix in ball form comprising cross-linked fibrinogen, the matrix being free from fibrin, as well as to a method for preparing such a matrix, comprising the following steps: (a) providing an initial composition comprising fibrinogen and a platelet factor; (b) injecting said initial composition into an oil heated to a temperature of 50° C. to 80° C. so as to form an emulsion; (c) mixing the emulsion thus obtained at a temperature of 50° C. to 80° C. until a matrix in ball form is obtained; and (d) isolating the matrix thus obtained. The matrix is used as a cell carrier.
    Type: Grant
    Filed: February 2, 2016
    Date of Patent: December 17, 2019
    Assignee: Maco Pharma
    Inventors: Thomas Bouckenooghe, Pauline Bertholet, Bruno Delorme
  • MATRIX IN BALL FORM AS A CELL CARRIER
    Publication number: 20180015147
    Abstract: The invention relates to a matrix in ball form comprising cross-linked fibrinogen, the matrix being free from fibrin, as well as to a method for preparing such a matrix, comprising the following steps: (a) providing an initial composition comprising fibrinogen and a platelet factor, (b) injecting said initial composition into an oil heated to a temperature of 50° C. to 80° C. so as to form an emulsion, (c) mixing the emulsion thus obtained at a temperature of 50° C. to 80° C. until a matrix in ball form is obtained, and (d) isolating the matrix thus obtained. The matrix is used as a cell carrier.
    Type: Application
    Filed: February 2, 2016
    Publication date: January 18, 2018
    Inventors: Thomas BOUCKENOOGHE, Pauline BERTHOLET, Bruno DELORME