Patents by Inventor Paulo Andres Garcia Dominguez

Paulo Andres Garcia Dominguez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microfluidic assay for rapid optimization of cell electroporation
    Patent number: 10947526
    Abstract: An electroporation device with a volume of varying cross sectional area that as a fast assay device for determining the optimal conditions for plasma membrane electroporation.
    Type: Grant
    Filed: December 10, 2014
    Date of Patent: March 16, 2021
    Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Cullen Richard Buie, Paulo Andres Garcia Dominguez, Zhifei Ge, Jeffrey Lawrence Moran
  • MICROFLUIDIC ASSAY FOR RAPID OPTIMIZATION OF CELL ELECTROPORATION
    Publication number: 20200332276
    Abstract: An electroporation device with a volume of varying cross-sectional area that be used as a fast assay device for determining the optimal conditions for plasma membrane electroporation.
    Type: Application
    Filed: July 6, 2020
    Publication date: October 22, 2020
    Inventors: Cullen Richard Buie, Paulo Andres Garcia Dominguez, Zhifei Ge, Jeffrey Lawrence Moran
  • Hydrodynamically Controlled Electric Fields for High Throughput Transformation & High Throughput Parallel Transformation Platform
    Publication number: 20190136224
    Abstract: Methods and apparatuses for cell electroporation are provided. An apparatus includes a fluid transport structure, such as a pipette, that includes an electroporation structure defining a flow path having a constriction. The fluid transport structure also includes at least two conductive elements configured to produce an electric field in the flow path. The conductive elements are in operative arrangement with each other and are configured to expose cells contained within a cell suspension flowing through the fluid transport structure to an electric field that is sufficient to electroporate at least a subset of the cells in the flow path.
    Type: Application
    Filed: May 31, 2017
    Publication date: May 9, 2019
    Inventors: Paulo Andres Garcia Dominguez, Zhifei Ge, Rameech N. McCormack, Cullen Richard Buie
  • Microfluidic Assay For Rapid Optimization Of Cell Electroporation
    Publication number: 20170218355
    Abstract: An electroporation device with a volume of varying cross sectional area that as a fast assay device for determining the optimal conditions for plasma membrane electroporation.
    Type: Application
    Filed: December 10, 2014
    Publication date: August 3, 2017
    Inventors: Cullen Richard Buie, Paulo Andres Garcia Dominguez, Zhifei Ge, Jeffrey Lawrence Moran