Abstract: A multiplexed lateral flow device includes an impermeable internal reservoir having an opening to receive a sample deposition. A fluid distributor pad is arranged in fluid communication with a lower surface of the internal reservoir. The fluid distributor pad includes a paper based microfluidic element having a pattern of a hydrophobic material to distribute a portion of the sample deposition substantially equally among a plurality of flow paths. Lateral flow assays having a plurality of flow lines are aligned with flow paths of the distributor pad. An impermeable top cover has a first window arranged over the opening of the internal reservoir, and at least a second window arranged over the test results of the lateral flow assays. A housing element houses the reservoir, the distributor pad and lateral flow assays.

Abstract: Systems and methods for optimizing factory scheduling, layout or both which represent active factory elements (human and machine) as computational objects and simulate factory operation to optimize a solution. This enables the efficient assembly of customized products, accommodates variable demand, and mitigates unplanned events (floor blockages, machines/IMRs/workcell/workers downtime, variable quantity, location, and destination of supply parts).

Abstract: A multiplexed lateral flow assay device includes an impermeable internal reservoir having an opening to receive a sample deposition. A fluid distributor pad is arranged in fluid communication with a lower surface of the internal reservoir and divides a portion of the sample deposition substantially equally among a plurality of flow paths. Lateral flow assays having a plurality of flow lines are aligned with flow paths of the distributor pad. An impermeable paper top cover has a first window arranged over the opening of the internal reservoir, and at least a second window arranged over the test results of the lateral flow assays. A housing element houses the reservoir, the distributor pad and lateral flow assays. The housing element includes an impermeable bottom cover and a spacer element arranged between the top and bottom covers and, provides a gap between the lateral flow assays and the impermeable paper top cover.

Abstract: The invention relates to a luminous motor-vehicle module including at least one light source, an open casing, and a closing element for closing said open casing. The open casing includes a housing for positioning on an optical element, the positioning housing includes a plurality of grooves, and a tab for hooking on a casing of said motor vehicle comprising the optical element and an outer lens for closing the casing, the luminous module being configured to make a rotation and hook, at the end of the rotation, onto the casing via said hooking tab of the open casing.

Abstract: This invention relates to atroipsomers of reduced tetraphenylporphyrin derivatives with halogen atoms (F, Cl, Br) in the ortho positions of the phenyl groups, particularly halogenated tetraphenylchlorins and halogenated tetraphenylbacteriochlorins, which can be used in photodynamic therapy. According to the formulae of the invention, the ortho-phenyl substituents X1, X2, X3, X4, X5, X6, X7 and X8 may be identical or different and represent halogen atoms or hydrogen atoms, provided that at least all of X2, X4, X6 and X8 are halogens, and the meta-phenyl substituents R1, R2, R3 and R4 are independently chosen from —OH, —OR or —SO2R?, where R? are each independently chosen from —Cl, —OH, -aminoacid, —OR, —NHR, or —NR2, where R are alkyl of 1 to 12 carbon atoms or R2 represents cycloalkyl with 2 to 12 carbon atoms. The atropisomers of this invention have the majority of the substituents R1, R2, R3 and R4 on the same side of the plane defined by the macrocycle.

Abstract: Telemetry data gathered from active deployed SAN nodes is used to create a machine learning model that predicts storage system performance, e.g. in terms of response time. The telemetry data may be filtered to remove outlier values and less relevant information before creating the training dataset. Engineered features may be created that include types of data that are not present in the telemetry data. For example, data types from the telemetry data may be combined to create engineered features that are more relevant than the individual data types. The engineered features are included in the training dataset. The machine learning model may be used to test possible configurations for a planned SAN node based on expected workload and performance requirements. Outputted data may include satisfactory configurations for a planned storage system.

Abstract: Patent for structure used in oyster cultivation, wherein the invention comprises a base (1), having four holes (2), where four pins are fixed, fixing the base to the bottom of the sea, base (1) has four other holes, wherein four vertical tubes (3) are fixed; after fixing tubes (3) to the base (1) of the structure, box (4) is settled over base (1), using tubes (3) as guides; afterwards, after putting oysters seeds in box (4), lid (5) is fixed over box (4), followed by sealing of lid (5), installed over box (4), in a way to avoid strange elements to the cultivation to access the oysters, then one end of rope (7) is fixed to ring (6) present in lid (5) and then the other end of rope (7) is fixed to counterweight (9), after passing this end of rope (7) by the hole present in buoy (8) (ring (6), fixed to one end of rope (7), buoy (8), counterweight (9), fixed to the other end of rope (7), help to maintain the structure stable in vertical position at the bottom of the sea during tide variations as well as during an

Abstract: Systems and methods for optimizing factory scheduling, layout or both which represent active factory elements (human and machine) as computational objects and simulate factory operation to optimize a solution. This enables the efficient assembly of customized products, accommodates variable demand, and mitigates unplanned events (floor blockages, machines/IMRs/workcell/workers downtime, variable quantity, location, and destination of supply parts).

Abstract: The invention relates to a luminous motor-vehicle module including at least one light source, an open casing, and a closing element for closing said open casing. The open casing includes a housing for positioning on an optical element, the positioning housing includes a plurality of grooves, and a tab for hooking on a casing of said motor vehicle comprising the optical element and an outer lens for closing the casing, the luminous module being configured to make a rotation and hook, at the end of the rotation, onto the casing via said hooking tab of the open casing.

Abstract: Systems and methods for optimizing factory scheduling, layout or both which represent active factory elements (human and machine) as computational objects and simulate factory operation to optimize a solution. This enables the efficient assembly of customized products, accommodates variable demand, and mitigates unplanned events (floor blockages, machines/IMRs/workcell/workers downtime, variable quantity, location, and destination of supply parts).

Abstract: A phosphine oxide compound represented by the following formula (I) and a rare earth complex containing the same are disclosed: wherein n represents an integer of 3 or more, Ar1 represents an n-valent aromatic group, L represents a divalent linker group, and Ar2 and Ar3 each independently represent a monovalent aromatic groups.

Abstract: Telemetry data gathered from active deployed SAN nodes is used to create a machine learning model that predicts storage system performance, e.g. in terms of response time. The telemetry data may be filtered to remove outlier values and less relevant information before creating the training dataset. Engineered features may be created that include types of data that are not present in the telemetry data. For example, data types from the telemetry data may be combined to create engineered features that are more relevant than the individual data types. The engineered features are included in the training dataset. The machine learning model may be used to test possible configurations for a planned SAN node based on expected workload and performance requirements. Outputted data may include satisfactory configurations for a planned storage system.

Abstract: A multiplexed lateral flow device includes an impermeable internal reservoir having an opening to receive a sample deposition. A fluid distributor pad is arranged in fluid communication with a lower surface of the internal reservoir. The fluid distributor pad includes a paper based microfluidic element having a pattern of a hydrophobic material to distribute a portion of the sample deposition substantially equally among a plurality of flow paths. Lateral flow assays having a plurality of flow lines are aligned with flow paths of the distributor pad. An impermeable top cover has a first window arranged over the opening of the internal reservoir, and at least a second window arranged over the test results of the lateral flow assays. A housing element houses the reservoir, the distributor pad and lateral flow assays.

Abstract: A multiplexed lateral flow assay device includes an impermeable internal reservoir having an opening to receive a sample deposition. A fluid distributor pad is arranged in fluid communication with a lower surface of the internal reservoir and divides a portion of the sample deposition substantially equally among a plurality of flow paths. Lateral flow assays having a plurality of flow lines are aligned with flow paths of the distributor pad. An impermeable paper top cover has a first window arranged over the opening of the internal reservoir, and at least a second window arranged over the test results of the lateral flow assays. A housing element houses the reservoir, the distributor pad and lateral flow assays. The housing element includes an impermeable bottom cover and a spacer element arranged between the top and bottom covers and, provides a gap between the lateral flow assays and the impermeable paper top cover.

Abstract: A deflector (38) including: a support (70); an intermediate member (72), pivotally mounted in the support (70) around a first rotation axis (B-B?); at least a secondary pivoting member (74), pivotally connected to the intermediate member (72) around a second rotation axis (C-C?) parallel to the first rotation axis (B-B?); for each secondary pivoting member (74), at least a pair of rotating members (76). Each rotating member (76) is connected to the secondary pivoting member (74). The deflector (38) including: a guiding mechanism, for guiding each rotating member (76) in translation with regard to the support (70) along a translation axis (D-D?) non parallel to the first rotation axis (B-B?); a connecting member (78), pivotally mounted to the secondary pivoting member (74). The rotating member (76) is rotatably mounted on the connecting member (78) around a rotating member rotation axis (E-E?).

Abstract: The present invention relates to carboxamide halogenated porphyrin derivatives, in particular bacteriochlorin or chlorin, of formula (I) use of the same or a pharmaceutically acceptable salt thereof in photodynamic therapy, where the derivatives are able to detect and exhibit the presence of hyperproliferative disorders and, in the presence of an adequate lighting, to treat the same. The present invention also describes a pharmaceutical composition having the carboxamide halogenated porphyrin derivatives, in particular bacteria-chlorin or chlorin, of Formula (I) or a pharmaceutically acceptable salt thereof, for the treatment of cancer and/or microbial and/or viral infections, in humans or animals.

Abstract: A deflector (38) including: a support (70); an intermediate member (72), pivotally mounted in the support (70) around a first rotation axis (B-B?); at least a secondary pivoting member (74), pivotally connected to the intermediate member (72) around a second rotation axis (C-C?) parallel to the first rotation axis (B-B?); for each secondary pivoting member (74), at least a pair of rotating members (76). Each rotating member (76) is connected to the secondary pivoting member (74). The deflector (38) including: a guiding mechanism, for guiding each rotating member (76) in translation with regard to the support (70) along a translation axis (D-D?) non parallel to the first rotation axis (B-B?); a connecting member (78), pivotally mounted to the secondary pivoting member (74). The rotating member (76) is rotatably mounted on the connecting member (78) around a rotating member rotation axis (E-E?).

Abstract: This invention relates to atroipsomers of reduced tetraphenylporphyrin derivatives with halogen atoms (F, Cl, Br) in the ortho positions of the phenyl groups, particularly halogenated tetraphenylchlorins and halogenated tetraphenylbacteriochlorins, which can be used in photodynamic therapy. According to the formulae of the invention, the ortho-phenyl substituents X1, X2, X3, X4, X5, X6, X7 and X8 may be identical or different and represent halogen atoms or hydrogen atoms, provided that at least all of X2, X4, X6 and X8 are halogens, and the meta-phenyl substituents R1, R2, R3 and R4 are independently chosen from —OH, —OR or —SO2R?, where R? are each independently chosen from —Cl, —OH, -aminoacid, —OR, —NHR, or —NR2, where R are alkyl of 1 to 12 carbon atoms or R2 represents cycloalkyl with 2 to 12 carbon atoms. The atropisomers of this invention have the majority of the substituents R1, R2, R3 and R4 on the same side of the plane defined by the macrocycle.

Abstract: The present invention relates to carboxamide halogenated porphyrin derivatives, in particular bacteriochlorin or chlorin, of formula (I) use of the same or a pharmaceutically acceptable salt thereof in photodynamic therapy, where the derivatives are able to detect and exhibit the presence of hyperproliferative disorders and, in the presence of an adequate lighting, to treat the same. The present invention also describes a pharmaceutical composition having the carboxamide halogenated porphyrin derivatives, in particular bacteria-chlorin or chlorin, of Formula (I) or a pharmaceutically acceptable salt thereof, for the treatment of cancer and/or microbial and/or viral infections, in humans or animals.

Abstract: A holding device for holding an element in sheet form 10 during its phase of insertion into a work station 300 of a converting machine 1. The holding device 310 includes a suction member 320 able to partially hold each sheet 10 by its rear portion during insertion of the sheet 10 into the work station 300. The holding device also includes a blower 330 able to flatten the rear portion of each sheet 10 against the suction member 320 during the phase of insertion.