Patents by Inventor Paulus Wohlfart

Paulus Wohlfart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4-Fluoro-N-indan-2-yl benzamide and its use as a pharmaceutical
    Patent number: 6812253
    Abstract: The present invention relates to the method of stimulating the expression of endothelial NO-synthase in a mammal, which method comprises administering a physiologically active amount of 4-fluoro-N-indan-2-yl benzamide according to the formula (I) to the said mammal.
    Type: Grant
    Filed: July 22, 2003
    Date of Patent: November 2, 2004
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Paulus Wohlfart, Teri Suzuki, Ramalinga M. Dharanipragada, Alena Safarova, Armin Walser, Hartmut Strobel
  • Use of EDG2 receptor in an animal model of heart failure
    Publication number: 20040132182
    Abstract: Mammals and myocardial mammal cells transformed with G protein coupled receptor EDG2 are presented for use in an animal model for heart failure.
    Type: Application
    Filed: November 12, 2003
    Publication date: July 8, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Evi Kostenis, Paulus Wohlfart, Jochen Huber, Kai Rosport, Andreas Bueltmann, Christine Baumgartner, Gotz Muench, Martin Ungerer
  • Acylated 6,7,8,9-tetrahydro-5H-benzocycloheptenyl amines and their use as pharmaceutical agents
    Patent number: 6759412
    Abstract: The present invention relates to compounds according to the general formula (I), wherein R1-R4 have the meanings given in the description, A is CH2, CHOH or CH—(C1-C3-alkyl), B, C and D are independently CH2 or CH—(C1-C3-alkyl), and R5 is an aryl or heteroaryl group, possibly substituted by the substituents listed in the description.
    Type: Grant
    Filed: February 13, 2002
    Date of Patent: July 6, 2004
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Hartmut Strobel, Paulus Wohlfart
  • Acylamino-substituted heteroaromatic compounds and their use as pharmaceuticals
    Publication number: 20040110808
    Abstract: The present invention relates to acylamino-substituted heteroaromatic compounds of formula I, 1
    Type: Application
    Filed: August 5, 2003
    Publication date: June 10, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Hartmut Strobel, Paulus Wohlfart, Peter Below
  • Acylated, heteroaryl-condensed cycloalkenylamines and their use as pharmaceuticals
    Publication number: 20040092513
    Abstract: The present invention relates to acylated, heteroaryl-condensed cycloalkenylamines, to pharmaceutical compositions comprising such compounds, to methods for the stimulation of the expression of endothelial NO synthase, and methods of treatment comprising administering such compounds.
    Type: Application
    Filed: July 31, 2003
    Publication date: May 13, 2004
    Applicant: AVENTIS PHARMA DEUTSCHLAND GMBH
    Inventors: Hartmut Strobel, Paulus Wohlfart
  • Acylated arylcycloalkylamines and their use as pharmaceuticals
    Publication number: 20040082628
    Abstract: The present invention relates to acylated arylcycloalkylamines, to pharmaceutical compositions comprising such compounds, to methods for the stimulation of the expression of endothelial NO synthase, and methods of treatment comprising administering such compounds.
    Type: Application
    Filed: August 7, 2003
    Publication date: April 29, 2004
    Applicant: AVENTIS PHARMA DEUTSCHLAND GMBH
    Inventors: Hartmut Strobel, Paulus Wohlfart, Peter Below
  • 4-Fluoro-N-indan-2-yl benzamide and its use as a pharmaceutical
    Publication number: 20040019114
    Abstract: The present invention relates to the method of stimulating the expression of endothelial NO-synthase in a mammal, which method comprises administering a physiologically active amount of 4-fluoro-N-indan-2-yl benzamide according to the formula (I) 1
    Type: Application
    Filed: July 22, 2003
    Publication date: January 29, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Paulus Wohlfart, Teri Suzuki, Ramalinga M. Dharanipragada, Alena Safarova, Armin Walser, Hartmut Strobel
  • 4-fluoro-N-indan-2-yl benzamide and its use as a pharmaceutical
    Patent number: 6617359
    Abstract: The present invention relates to the method of stimulating the expression of endothelial NO-synthase in a mammal, which method comprises administering a physiologically active amount of 4-fluoro-N-indan-2-yl benzamide according to the formula (I) to the said mammal.
    Type: Grant
    Filed: February 13, 2002
    Date of Patent: September 9, 2003
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Paulus Wohlfart, Teri Suzuki, Ramalinga M. Dharanipragada, Alena Safarova, Armin Walser, Hartmut Strobel
  • Acylated indanyl amines and their use as pharmaceuticals
    Publication number: 20030055093
    Abstract: The present invention relates to acylated indanyl amines according to the general formula (I) 1
    Type: Application
    Filed: February 13, 2002
    Publication date: March 20, 2003
    Inventors: Hartmut Strobel, Paulus Wohlfart, Alena Safarova, Armin Walser, Teri Suzuki, Karl Schonafinger, Ramalinga M. Dharanipragada
  • Acylated 1,2,3,4-tetrahydronaphthyl amines and their use as pharmaceutical agents
    Publication number: 20030022935
    Abstract: The present invention relates to compounds of general formula (I), 1
    Type: Application
    Filed: February 13, 2002
    Publication date: January 30, 2003
    Inventors: Hartmut Strobel, Paulus Wohlfart
  • 4-Fluoro-N- indan-2-yl benzamide and its use as a pharmaceutical
    Publication number: 20030022939
    Abstract: The present invention relates to the method of stimulating the expression of endothelial NO-synthase in a mammal, which method comprises administering a physiologically active amount of 4-fluoro-N-indan-2-yl benzamide according to the formula (I) 1
    Type: Application
    Filed: February 13, 2002
    Publication date: January 30, 2003
    Inventors: Paulus Wohlfart, Teri Suzuki, Ramalinga M. Dharanipragada, Alena Safarova, Armin Walser, Hartmut Strobel
  • Acylated 6,7,8,9-tetrahydro-5H-benzocycloheptenyl amines and their use as pharmaceutical agents
    Publication number: 20030008915
    Abstract: The present invention relates to compounds according to the general formula (I), 1
    Type: Application
    Filed: February 13, 2002
    Publication date: January 9, 2003
    Inventors: Hartmut Strobel, Paulus Wohlfart