Patents by Inventor Pavan Kumar TOGAPUR

Pavan Kumar TOGAPUR has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Indole (sulfomyl) n-hydroxy benzamide derivatives as selective HDAC inhibitors
    Patent number: 11072583
    Abstract: Sulfonyl hydroxamic acid compounds have the following general formula: Ring A and B are aryl, heteroaryl, cycloalkyl, fused aryl or fused alkyl group, and R1, R2, R3, R4, R5, and R6 are hydrogen, alkoxy, aryloxy, hydroxy, ester, amide, amino, alkyl, aryl, heteroaryl, halogen, hydroxy, alkoxy, aryloxy, nitro, cyano, ester, or aldehyde. The compounds are HDAC inhibitors. Processes can be used for preparation of these indole-based sulfonyl hydroxamic acid derivatives.
    Type: Grant
    Filed: August 6, 2018
    Date of Patent: July 27, 2021
    Assignee: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Chandrasekhar Srivari, Prathama Satyendra Mainkar, Chada Raji Reddy, Srigiridhar Kotamraju, Pavan Kumar Togapur, Subbarao Mohan Venkata Muppidi, Somesh Sharma, Ashok Kumar Jha, Prem Kumar Arumugam
  • INDOLE (SULFOMYL) N-HYDROXY BENZAMIDE DERIVATIVES AS SELECTIVE HDAC INHIBITORS
    Publication number: 20200385349
    Abstract: Sulfonyl hydroxamic acid compounds have the following general formula: Ring A and B are aryl, heteroaryl, cycloalkyl, fused aryl or fused alkyl group, and R1, R2, R3, R4, R5, and R6 are hydrogen, alkoxy, aryloxy, hydroxy, ester, amide, amino, alkyl, aryl, heteroaryl, halogen, hydroxy, alkoxy, aryloxy, nitro, cyano, ester, or aldehyde. The compounds are HDAC inhibitors. Processes can be used for preparation of these indole-based sulfonyl hydroxamic acid derivatives.
    Type: Application
    Filed: August 6, 2018
    Publication date: December 10, 2020
    Inventors: Chandrasekhar SRIVARI, Prathama Satyendra MAINKAR, Chada Raji REDDY, Srigiridhar KOTAMRAJU, Pavan Kumar TOGAPUR, Subbarao Mohan Venkata MUPPIDI, Somesh SHARMA, Ashok Kumar JHA, Prem Kumar ARUMUGAM
  • Process for the preparation of Zafirlukast and analogs thereof
    Patent number: 10752585
    Abstract: The present invention relates to a process for the preparation of (1-alkylindol-3-ylmethyl) benzoic acid derivatives, in particular Zafirlukast and analogs thereof. Further, this process is based on protection group free and C—H bond activation strategy involving all step catalytic transformation sequence and comprises the following steps: Sonogashira coupling, indole formation by Sp3 C—H activation, reductive hydrogenation and amidation.
    Type: Grant
    Filed: August 6, 2018
    Date of Patent: August 25, 2020
    Assignee: Council of Scientific & Industrial Research
    Inventors: Chandrasekhar Srivari, Prathama Satyendra Mainkar, Srinu Paladugu, Pavan Kumar Togapur
  • PROCESS FOR THE PREPARATION OF ZAFIRLUKAST AND ANALOGS THEREOF
    Publication number: 20200216390
    Abstract: The present invention relates to a process for the preparation of (1-alkylindo-3-ylmethyl) benzoic acid derivatives, in particular Zafirlukast and analogs thereof. Further, this process is based on protection group free and C—H bond activation strategy involving all step catalytic transformation sequence and comprises the following steps: Sonogashira coupling, indole formation by Sp3 C—H activation, reductive hydrogenation and amidation.
    Type: Application
    Filed: August 6, 2018
    Publication date: July 9, 2020
    Inventors: Chandrasekhar SRIVARI, Prathama Satyendra MAINKAR, Srinu PALADUGU, Pavan Kumar TOGAPUR