Patents by Inventor Pavel Dolezal

Pavel Dolezal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Carrier for oromucosal administration of physiologically active substances
    Patent number: 11771648
    Abstract: The invention relates to a carrier for oromucosal, especially sublingual administration of physiologically active substances, especially of medicinal drugs, which consists of at least one elastic layer (1) of polymer nanofibres workable according to the shape of the selected wall of mouth cavity to which it should be applied and in this elastic layer (1) of polymer nanofibres a drug and/or other physiologically active substance are deposited in a releasable manner.
    Type: Grant
    Filed: May 5, 2020
    Date of Patent: October 3, 2023
    Assignee: INSTAR TECHNOLOGIES A.S.
    Inventors: Denisa Stranska, Adela Klabanova, Pavel Dolezal, Petr Vrbata, Pavel Berka, Marie Musilova
  • Pharmaceutical composition containing a mixture of proenzymes and enzymes
    Patent number: 11185587
    Abstract: Pharmaceutical composition containing a mixture of proenzymes and enzymes, containing proenzymes trypsinogen and chymotrypsinogen and enzymes ?-amylase and lipase as active substances, and one or more pharmaceutically acceptable excipients, for simultaneous, separate and subsequent administration of the composition in parenteral or transmucosal way, the composition has anti-proliferative and anti-metastatic effects to cancer tumours and is intended for therapeutic, prophylactic and anti-metastatic use in mammals.
    Type: Grant
    Filed: February 21, 2019
    Date of Patent: November 30, 2021
    Inventors: Frantisek Trnka, Pavel Dolezal
  • OROMUCOSAL NANOFIBER CARRIERS FOR THERAPEUTIC TREATMENT
    Publication number: 20210069122
    Abstract: The present disclosure relates to oromucosal nanofiber carriers that are mucoadhesive or comprise a mucoadhesive agent for administration of active agents, including substances for their preparation, methods of preparation, and methods of use.
    Type: Application
    Filed: January 27, 2017
    Publication date: March 11, 2021
    Applicant: Instar Technologies A.S.
    Inventors: Denisa STRÁNSKÁ, Jana SVOBODOVA, Pavel BERKA, Pavel DOLEZAL
  • CARRIER FOR OROMUCOSAL ADMINISTRATION OF PHYSIOLOGICALLY ACTIVE SUBSTANCES
    Publication number: 20200261353
    Abstract: The invention relates to a carrier for oromucosal, especially sublingual administration of physiologically active substances, especially of medicinal drugs, which consists of at least one elastic layer (1) of polymer nanofibres workable according to the shape of the selected wall of mouth cavity to which it should be applied and in this elastic layer (1) of polymer nanofibres a drug and/or other physiologically active substance are deposited in a releasable manner.
    Type: Application
    Filed: May 5, 2020
    Publication date: August 20, 2020
    Applicant: INSTAR TECHNOLOGIES A.S.
    Inventors: Denisa STRANSKA, Adela KLABANOVA, Pavel DOLEZAL, Petr VRBATA, Pavel BERKA, Marie MUSILOVA
  • PHARMACEUTICAL COMPOSITION CONTAINING A MIXTURE OF PROENZYMES AND ENZYMES
    Publication number: 20190247471
    Abstract: Pharmaceutical composition containing a mixture of proenzymes and enzymes, containing proenzymes trypsinogen and chymotrypsinogen and enzymes ?-amylase and lipase as active substances, and one or more pharmaceutically acceptable excipients, for simultaneous, separate and subsequent administration of the composition in parenteral or transmucosal way, the composition has anti-proliferative and anti-metastatic effects to cancer tumours and is intended for therapeutic, prophylactic and anti-metastatic use in mammals.
    Type: Application
    Filed: February 21, 2019
    Publication date: August 15, 2019
    Inventors: Frantisek TRNKA, Pavel DOLEZAL
  • CARRIER FOR OROMUCOSAL ADMINISTRATION OF PHYSIOLOGICALLY ACTIVE SUBSTANCES
    Publication number: 20180064636
    Abstract: The invention relates to a carrier for oromucosal, especially sublingual administration of physiologically active substances, especially of medicinal drugs, which consists of at least one elastic layer (1) of polymer nanofibres workable according to the shape of the selected wall of mouth cavity to which it should be applied and in this elastic layer (1) of polymer nanofibres a drug and/or other physiologically active substance are deposited in a releasable manner.
    Type: Application
    Filed: September 22, 2017
    Publication date: March 8, 2018
    Applicant: INSTAR TECHNOLOGIES A.S.
    Inventors: Denisa STRANSKA, Adela KLABANOVA, Pavel DOLEZAL, Petr VRBATA, Pavel BERKA, Marie MUSILOVA
  • Carrier for oromucosal administration of physiologically active substances
    Patent number: 9789060
    Abstract: The present disclosure relates to a carrier for oromucosal, especially sublingual administration of physiologically active substances, especially of medicinal drugs, which consists of at least one elastic layer (1) of polymer nanofibers workable according to the shape of the selected wall of mouth cavity to which it should be applied and in this elastic layer (1) of polymer nanofibers a drug and/or other physiologically active substance are deposited in a releasable manner.
    Type: Grant
    Filed: December 12, 2011
    Date of Patent: October 17, 2017
    Assignee: INSTAR TECHNOLOGIES A.S.
    Inventors: Denisa Stranska, Adela Klabanova, Pavel Dolezal, Petr Vrbata, Pavel Berka, Marie Musilova
  • PHARMACEUTICAL COMPOSITION CONTAINING A MIXTURE OF PROENZYMES AND ENZYMES
    Publication number: 20160339085
    Abstract: Pharmaceutical composition containing a mixture of proenzymes and enzymes, containing proenzymes trypsinogen and chymotrypsinogen and enzymes ct-amylase and lipase as active substances, and one or more pharmaceutically acceptable excipients, for simultaneous, separate and subsequent administration of the composition in parenteral or transmucosal way, the composition has anti-proliferative and anti-metastatic effects to cancer tumours and is intended for therapeutic, prophylactic and anti-metastatic use in mammals.
    Type: Application
    Filed: November 24, 2014
    Publication date: November 24, 2016
    Inventors: Frantisek TRNKA, Pavel DOLEZAL
  • CARRIER FOR OROMUCOSAL, ESPECIALLY SUBLINGUAL ADMINISTRATION OF PHYSIOLOGICALLY ACTIVE SUBSTANCES
    Publication number: 20130323296
    Abstract: The present disclosure relates to a carrier for oromucosal, especially sublingual administration of physiologically active substances, especially of medicinal drugs, which consists of at least one elastic layer (1) of polymer nanofibres workable according to the shape of the selected wall of mouth cavity to which it should be applied and in this elastic layer (1) of polymer nanofibres a drug and/or other physiologically active substance are deposited in a releasable manner.
    Type: Application
    Filed: December 12, 2011
    Publication date: December 5, 2013
    Inventors: Denisa Stranska, Adela Klabanova, Pavel Dolezal, Petr Vrbata, Pavel Berka, Marie Musilova