Patents by Inventor Pavel Idelevich

Pavel Idelevich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220304951
    Abstract: In one aspect, the invention generally relates to anticancer compositions comprising new fuchsine and methods for using the anticancer compositions. In one aspect, the invention provides a method for treating a disorder of uncontrolled cellular proliferation in a cell of a subject, the method comprising the step of providing to the cell an effective amount of at least one fuchsine compound or a pharmaceutically acceptable salt thereof. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: March 28, 2022
    Publication date: September 29, 2022
    Inventor: Pavel Idelevich
  • Patent number: 10928405
    Abstract: Some embodiments of the present invention generally relate to devices and methods for determining and/or isolating cells. For example, one aspect is generally directed to methods and devices for detecting, identifying, counting, and/or potentially sorting cells of interest in blood or other biological sample. In some embodiments, blood samples (or other biological fluids) may be treated with signaling entities, such as pH-sensitive entities, that change color or otherwise produce a signal in suitable internal environments. For example, certain cells, such as cancer or fetal cells, may have differences in intracellular pH compared to other cells, which can be detected using pH-sensitive entities. In certain embodiments, the cells may be sorted based on such signaling entities; for example, illumination of cells in a suitable machine for sorting cells (e.g., using fluorescent light) may allow determination of the cells, which may also be recovered or isolated for further manipulation in some cases.
    Type: Grant
    Filed: December 4, 2018
    Date of Patent: February 23, 2021
    Assignee: Analiza, Inc.
    Inventors: Pavel Idelevich, Arnon Chait, Alan Bauer, Paul David Jackson
  • Publication number: 20200109394
    Abstract: The invention generally relates to compositions and methods for isolating circulating cells. In one aspect, the invention provides a method for isolating one or more target cells in a biological fluid of a subject, the method comprising: selectively providing to the one or more target cells an effective amount of at least one iron saccharide complex or a pharmaceutically acceptable derivative thereof; and isolating the target cells using a magnetic source capable of generating a magnetic field effective to capture target cells containing a magnetically responsive intracellular concentration of the of at least one iron saccharide complex or a pharmaceutically acceptable derivative thereof in the magnetic field. In further aspects, the method can comprise treating the target cell will one or more cancer treatments. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: October 3, 2019
    Publication date: April 9, 2020
    Inventors: Pavel Idelevich, Arnon Chait
  • Publication number: 20200046746
    Abstract: The invention generally relates to anti-aging compositions and methods for using the anti-aging compositions. In one aspect, the invention provides a method for preventing cellular aging in a cell of a subject, the method comprising the step of providing to the cell an effective amount of at least one lithium compound or a pharmaceutically acceptable salt thereof, and an effective amount of at least one glycyrrhizie triterpenoid compound or a pharmaceutically acceptable salt thereof, thereby preventing the cell from aging. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: October 17, 2019
    Publication date: February 13, 2020
    Inventors: Pavel Idelevich, Anna Idelevich
  • Patent number: 10363263
    Abstract: The invention generally relates to anti-aging compositions and methods for using the anti-aging compositions. In one aspect, the invention provides a method for preventing cellular aging in a cell of a subject, the method comprising the step of providing to the cell an effective amount of at least one lithium compound or a pharmaceutically acceptable salt thereof, and an effective amount of at least one glycyrrhizie triterpenoid compound or a pharmaceutically acceptable salt thereof, thereby preventing the cell from aging. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: November 3, 2016
    Date of Patent: July 30, 2019
    Assignee: Prescient Pharma, LLC
    Inventors: Pavel Idelevich, Anna Idelevich
  • Publication number: 20190178901
    Abstract: Some embodiments of the present invention generally relate to devices and methods for determining and/or isolating cells. For example, one aspect is generally directed to methods and devices for detecting, identifying, counting, and/or potentially sorting cells of interest in blood or other biological sample. In some embodiments, blood samples (or other biological fluids) may be treated with signaling entities, such as pH-sensitive entities, that change color or otherwise produce a signal in suitable internal environments. For example, certain cells, such as cancer or fetal cells, may have differences in intracellular pH compared to other cells, which can be detected using pH-sensitive entities. In certain embodiments, the cells may be sorted based on such signaling entities; for example, illumination of cells in a suitable machine for sorting cells (e.g., using fluorescent light) may allow determination of the cells, which may also be recovered or isolated for further manipulation in some cases.
    Type: Application
    Filed: December 4, 2018
    Publication date: June 13, 2019
    Applicant: Analiza, Inc.
    Inventors: Pavel Idelevich, Arnon Chait, Alan Bauer, Paul David Jackson
  • Publication number: 20190083526
    Abstract: The invention generally relates to methods of treating short telomere disorders using known compounds and pharmaceutical compositions comprising same. More specifically, the disclosed methods comprise, in one aspect, the step of administering to the subject an effective amount of at least one lithium compound or a pharmaceutically acceptable salt thereof, thereby treating the subject for the short telomere disorder. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: August 13, 2018
    Publication date: March 21, 2019
    Inventors: Pavel Idelevich, Yanming Wang
  • Publication number: 20180318324
    Abstract: The invention generally relates to anti-aging compositions and methods for using the anti-aging compositions. In one aspect, the invention provides a method for preventing cellular aging in a cell of a subject, the method comprising the step of providing to the cell an effective amount of at least one lithium compound or a pharmaceutically acceptable salt thereof, and an effective amount of at least one glycyrrhizie triterpenoid compound or a pharmaceutically acceptable salt thereof, thereby preventing the cell from aging. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: November 3, 2016
    Publication date: November 8, 2018
    Inventors: Pavel Idelevich, Anna Idelevich
  • Patent number: 10046007
    Abstract: The invention generally relates to methods of treating short telomere disorders using known compounds and pharmaceutical compositions comprising same. More specifically, the disclosed methods comprise, in one aspect, the step of administering to the subject an effective amount of at least one lithium compound or a pharmaceutically acceptable salt thereof, thereby treating the subject for the short telomere disorder. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: June 24, 2016
    Date of Patent: August 14, 2018
    Assignee: Prescient Pharma, LLC
    Inventors: Pavel Idelevich, Yanming Wang
  • Patent number: 10018622
    Abstract: Methods and kits for identifying abnormal urinary system cells in a sample, by contacting the cells or the sample containing same with a combination of an extract from a Ficus plant, or one or more components thereof, an acidic dye and a basic dye.
    Type: Grant
    Filed: May 18, 2015
    Date of Patent: July 10, 2018
    Assignee: ZETIQ TECHNOLOGIES LTD.
    Inventors: Pavel Idelevich, Adi Elkeles, Dov Terkieltaub, Ami Eyal, Dan Jacob Gelvan
  • Patent number: 9709556
    Abstract: The present invention generally relates to devices and methods for determining and/or isolating cells. One aspect is generally directed to methods and devices for detecting, identifying, counting, and/or potentially sorting cells of interest in blood or other biological sample. In some embodiments, blood samples (or other biological fluids) may be treated with signaling entities, such as pH-sensitive entities, that change color or otherwise produce a signal in suitable internal environments. For example, certain cells, such as cancer or fetal cells, may have differences in intracellular pH compared to other cells, which can be detected using pH-sensitive entities. In certain embodiments, the cells may be sorted based on such signaling entities; for example, illumination of cells in a suitable machine for sorting cells (e.g., using fluorescent light) may allow determination of the cells, which may also be recovered or isolated for further manipulation in some cases.
    Type: Grant
    Filed: March 26, 2014
    Date of Patent: July 18, 2017
    Assignee: Analiza, Inc.
    Inventors: Pavel Idelevich, Arnon Chait, Alan Bauer
  • Publication number: 20170182075
    Abstract: The invention generally relates to anti-aging compositions and methods for using the anti-aging compositions. In one aspect, the invention provides a method for preventing cellular aging in a cell of a subject, the method comprising the step of providing to the cell an effective amount of at least one lithium compound or a pharmaceutically acceptable salt thereof, and an effective amount of at least one glycyrrhizie triterpenoid compound or a pharmaceutically acceptable salt thereof, thereby preventing the cell from aging. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: November 3, 2016
    Publication date: June 29, 2017
    Inventors: Pavel Idelevich, Anna Idelevich
  • Publication number: 20160375052
    Abstract: The invention generally relates to methods of treating short telomere disorders using known compounds and pharmaceutical compositions comprising same. More specifically, the disclosed methods comprise, in one aspect, the step of administering to the subject an effective amount of at least one lithium compound or a pharmaceutically acceptable salt thereof, thereby treating the subject for the short telomere disorder. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: June 24, 2016
    Publication date: December 29, 2016
    Inventors: Pavel Idelevich, Yanming Wang
  • Patent number: 9182403
    Abstract: Provided are methods and kits for staining cervical cell sample by contacting the cervical cell sample with a Ficus elastics plant extract, staining the cervical cell sample with New Fuchsin, and staining the cervical cell sample with Light Green or Fast Green. Also provided are method of diagnosing a pre-malignant or a malignant cervical tumor in a subject, by staining the cervical cell sample and identifying at least one cervical cell having a red cytoplasm above a pre-determined threshold, wherein presence of the at least one cervical cell having the red cytoplasm above the pre-determined threshold is indicative of a non- or less-differentiated cell as compared to a normal cervical cell, thereby diagnosing the pre-malignant or a malignant cervical tumor in the subject.
    Type: Grant
    Filed: May 17, 2010
    Date of Patent: November 10, 2015
    Assignee: Zetiq Technologies LTD.
    Inventors: Pavel Idelevich, Adi Elkeles, Dov Terkieltaub, Ami Eyal
  • Publication number: 20150253310
    Abstract: Methods and kits for identifying abnormal urinary system cells in a sample, by contacting the cells or the sample containing same with a combination of an extract from a Ficus plant, or one or more components thereof, an acidic dye and a basic dye.
    Type: Application
    Filed: May 18, 2015
    Publication date: September 10, 2015
    Inventors: Pavel Idelevich, Adi Elkeles, Dov Terkieltaub, Ami Eyal
  • Patent number: 9063127
    Abstract: The present invention generally relates to devices and methods for determining and/or isolating cells. One aspect is generally directed to methods and devices for detecting, identifying, counting, and/or potentially sorting cells of interest in blood or other biological sample. In some embodiments, blood samples (or other biological fluids) may be treated with signaling entities, such as pH-sensitive entities, that change color or otherwise produce a signal in suitable internal environments. For example, certain cells, such as cancer or fetal cells, may have differences in intracellular pH compared to other cells, which can be detected using pH-sensitive entities. In certain embodiments, the cells may be sorted based on such signaling entities; for example, illumination of cells in a suitable machine for sorting cells (e.g., using fluorescent light) may allow determination of the cells, which may also be recovered or isolated for further manipulation in some cases.
    Type: Grant
    Filed: June 24, 2014
    Date of Patent: June 23, 2015
    Assignee: Analiza, Inc.
    Inventors: Pavel Idelevich, Arnon Chait, Alan Bauer
  • Publication number: 20150160198
    Abstract: The present invention generally relates to devices and methods for determining and/or isolating cells. One aspect is generally directed to methods and devices for detecting, identifying, counting, and/or potentially sorting cells of interest in blood or other biological sample. In some embodiments, blood samples (or other biological fluids) may be treated with signaling entities, such as pH-sensitive entities, that change color or otherwise produce a signal in suitable internal environments. For example, certain cells, such as cancer or fetal cells, may have differences in intracellular pH compared to other cells, which can be detected using pH-sensitive entities. In certain embodiments, the cells may be sorted based on such signaling entities; for example, illumination of cells in a suitable machine for sorting cells (e.g., using fluorescent light) may allow determination of the cells, which may also be recovered or isolated for further manipulation in some cases.
    Type: Application
    Filed: June 24, 2014
    Publication date: June 11, 2015
    Applicant: Analiza, Inc.
    Inventors: Pavel Idelevich, Arnon Chait, Alan Bauer
  • Publication number: 20150160196
    Abstract: The present invention generally relates to devices and methods for determining and/or isolating cells. One aspect is generally directed to methods and devices for detecting, identifying, counting, and/or potentially sorting cells of interest in blood or other biological sample. In some embodiments, blood samples (or other biological fluids) may be treated with signaling entities, such as pH-sensitive entities, that change color or otherwise produce a signal in suitable internal environments. For example, certain cells, such as cancer or fetal cells, may have differences in intracellular pH compared to other cells, which can be detected using pH-sensitive entities. In certain embodiments, the cells may be sorted based on such signaling entities; for example, illumination of cells in a suitable machine for sorting cells (e.g., using fluorescent light) may allow determination of the cells, which may also be recovered or isolated for further manipulation in some cases.
    Type: Application
    Filed: March 26, 2014
    Publication date: June 11, 2015
    Applicant: Analiza, Inc.
    Inventors: Pavel Idelevich, Arnon Chait, Alan Bauer
  • Publication number: 20150160246
    Abstract: Some embodiments of the present invention generally relate to devices and methods for determining and/or isolating cells. For example, one aspect is generally directed to methods and devices for detecting, identifying, counting, and/or potentially sorting cells of interest in blood or other biological sample. In some embodiments, blood samples (or other biological fluids) may be treated with signaling entities, such as pH-sensitive entities, that change color or otherwise produce a signal in suitable internal environments. For example, certain cells, such as cancer or fetal cells, may have differences in intracellular pH compared to other cells, which can be detected using pH-sensitive entities. In certain embodiments, the cells may be sorted based on such signaling entities; for example, illumination of cells in a suitable machine for sorting cells (e.g., using fluorescent light) may allow determination of the cells, which may also be recovered or isolated for further manipulation in some cases.
    Type: Application
    Filed: December 8, 2014
    Publication date: June 11, 2015
    Applicant: Analiza, Inc.
    Inventors: Pavel Idelevich, Arnon Chait, Alan Bauer, Paul David Jackson
  • Publication number: 20130266960
    Abstract: A method of conditioning urinary system cells for identification of abnormal cells is provided. The method is effected by contacting the urinary system cells with an extract from a Ficus plant or one or more components thereof thereby conditioning the abnormal cells for identification. Methods for subsequent detection of the abnormal cells are also provided.
    Type: Application
    Filed: May 22, 2013
    Publication date: October 10, 2013
    Inventors: Pavel Idelevich, Adi Elkeles, Dov Terkieltaub, Ami Eyal