Patents by Inventor Pavel Krasik

Pavel Krasik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthetic process for preparing 2-furoic acid derivatives
    Patent number: 9975867
    Abstract: Disclosed herein are processes for forming 2-furoic acid derivatives represented by Formula (I):
    Type: Grant
    Filed: February 4, 2016
    Date of Patent: May 22, 2018
    Assignee: Dermira Inc.
    Inventors: Anthony Adrian Shaw, Kanjai Khumtaveeporn, Pavel Krasik
  • DERMATOLOGICAL FORMULATIONS OF 2-(2-ETHOXY-2-OXOETHYL)(METHYL)AMINO-2-OXOETHYL 5-(TETRADECYLOXY)FURAN-2-CARBOXYLATE
    Publication number: 20180028487
    Abstract: Disclosed herein are dermatological formulations comprising low-impurity TOFA prodrug 2-(2-ethoxy-2-oxoethyl)(methyl)amino-2-oxoethyl 5-(tetradecyloxy)furan-2-carboxylate represented by Formula (Ia) and pharmaceutical use thereof:
    Type: Application
    Filed: July 26, 2017
    Publication date: February 1, 2018
    Inventors: Anthony Adrian Shaw, Kanjai Khumtaveeporn, Pavel Krasik
  • Synthetic process for preparing 2-((2-ethoxy-2-oxoethyl)(methyl)amino)-2-oxoethyl 5-tetradecyloxy)furan-2-carboxylate
    Patent number: 9745277
    Abstract: Disclosed herein are processes for forming 2-((2-ethoxy-2-oxoethyl)(methyl)amino)-2-oxoethyl 5-tetradecyloxy)furan-2-carboxylate:
    Type: Grant
    Filed: October 3, 2016
    Date of Patent: August 29, 2017
    Assignee: Dermira Inc.
    Inventors: Anthony Adrian Shaw, Kanjai Khumtaveeporn, Pavel Krasik
  • SYNTHETIC PROCESS FOR PREPARING 2-((2-ETHOXY-2-OXOETHYL)(METHYL)AMINO)-2-OXOETHYL 5-TETRADECYLOXY)FURAN-2-CARBOXYLATE
    Publication number: 20170022176
    Abstract: Disclosed herein are processes for forming 2-((2-ethoxy-2-oxoethyl)(methyl)amino)-2-oxoethyl 5-tetradecyloxy)furan-2-carboxylate:
    Type: Application
    Filed: October 3, 2016
    Publication date: January 26, 2017
    Inventors: Anthony Adrian Shaw, Kanjai Khumtaveeporn, Pavel Krasik
  • Synthetic process for preparing 2-((2-ethoxy-2-oxoethyl)(methyl)amino)-2-oxoethyl 5-tetradecyloxy)furan-2-carboxylate
    Patent number: 9487497
    Abstract: Disclosed herein are processes for forming 2-((2-ethoxy-2-oxoethyl)(methyl)amino)-2-oxoethyl 5-tetradecyloxy)furan-2-carboxylate:
    Type: Grant
    Filed: February 4, 2016
    Date of Patent: November 8, 2016
    Assignee: DERMIRA INC.
    Inventors: Anthony Adrian Shaw, Kanjai Khumtaveeporn, Pavel Krasik
  • SYNTHETIC PROCESS FOR PREPARING 2-((2-ETHOXY-2-OXOETHYL)(METHYL)AMINO)-2-OXOETHYL 5-TETRADECYLOXY)FURAN-2-CARBOXYLATE
    Publication number: 20160229826
    Abstract: Disclosed herein are processes for forming 2-((2-ethoxy-2-oxoethyl)(methyl)amino)-2-oxoethyl 5-tetradecyloxy)furan-2-carboxylate:
    Type: Application
    Filed: February 4, 2016
    Publication date: August 11, 2016
    Inventors: Anthony Adrian Shaw, Kanjai Khumtaveeporn, Pavel Krasik
  • SYNTHETIC PROCESS FOR PREPARING 2-FUROIC ACID DERIVATIVES
    Publication number: 20160229825
    Abstract: Disclosed herein are processes for forming 2-furoic acid derivatives represented by Formula (I):
    Type: Application
    Filed: February 4, 2016
    Publication date: August 11, 2016
    Inventors: Anthony Adrian Shaw, Kanjai Khumtaveeporn, Pavel Krasik
  • Methods of synthesis of benzazepine derivatives
    Patent number: 8314090
    Abstract: The disclosure describes method of synthesis of substituted benzazepine derivatives. Preferred methods according to the disclosure allow for large-scale preparation of benzazepine compounds having low levels of metal impurities. In some embodiments, preferred methods according to the disclosure also allow for the preparation of benzazepine derivatives without the use of chromatographic purification methods and in better yield than previously used methods for preparing such compounds. The methods disclosed herein find utility in synthetic organic chemistry as well as medicinal chemistry.
    Type: Grant
    Filed: November 6, 2009
    Date of Patent: November 20, 2012
    Assignees: VentiRx Pharmaceuticals, Inc., Array BioPharma, Inc.
    Inventors: J. Jeffry Howbert, Venkat Reddy Kusukuntla, Alexander Tretyakov, Nathan Nielsen, Pavel Krasik, Ji-Long Jiang, Hong Woon Yang
  • METHODS OF SYNTHESIS OF BENZAZEPINE DERIVATIVES
    Publication number: 20100216989
    Abstract: The disclosure describes method of synthesis of substituted benzazepine derivatives. Preferred methods according to the disclosure allow for large-scale preparation of benzazepine compounds having low levels of metal impurities. In some embodiments, preferred methods according to the disclosure also allow for the preparation of benzazepine derivatives without the use of chromatographic purification methods and in better yield than previously used methods for preparing such compounds. The methods disclosed herein find utility in synthetic organic chemistry as well as medicinal chemistry.
    Type: Application
    Filed: November 6, 2009
    Publication date: August 26, 2010
    Applicants: VentiRx Pharmaceuticals, Inc., Array BioPharma, Inc.
    Inventors: J. Jeffry Howbert, Venkat R. Kusukuntla, Alexander Tretyakov, Nathan Nielsen, Pavel Krasik, Ji-Long Jiang, Hong Woon Yang