Patents by Inventor Pavel Ovcharov

Pavel Ovcharov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250029240
    Abstract: Techniques for identifying a tertiary lymphoid structure (TLS) in an image of tissue. The techniques include obtaining a set of overlapping sub-images of the image; processing the set of overlapping sub-images using a neural network model to obtain a set of pixel-level sub-image masks, each of the set of pixel-level sub-image masks indicating, for each of multiple pixels in a respective sub-image, a probability that the pixel is part of a TLS; determining a pixel-level mask for at least a portion of the image covered by at least some of the sub-images, the determining comprising determining the pixel-level mask using at least some of the set of pixel-level sub-image masks; identifying boundaries of a TLS in at least the portion of the image using the pixel-level mask; and identifying one or more features of the TLS using the identified boundaries and at least the portion of the image.
    Type: Application
    Filed: February 14, 2023
    Publication date: January 23, 2025
    Applicant: BostonGene Corporation
    Inventors: Vladimir Kushnarev, Anna Belozerova, Daniil Dymov, Pavel Ovcharov, Viktor Svekolkin, Alexander Bagaev, Zhongmin Xiang
  • Publication number: 20240295486
    Abstract: Techniques for identifying types of cells present in a biological sample using flow cytometry performed using a panel of markers and multiple machine learning models. The techniques include: obtaining flow cytometry data for the biological sample, the biological sample previously-obtained from a subject and comprising a plurality of cells, the flow cytometry data including flow cytometry measurements obtained during respective flow cytometry events, the flow cytometry events including a subset of events corresponding to cells in the biological sample being measured by the flow cytometry platform; and identifying types of cells of the plurality of cells using the multiple machine learning models to obtain a respective plurality of cell types.
    Type: Application
    Filed: March 1, 2024
    Publication date: September 5, 2024
    Inventors: Aleksandr Zaitsev, Dmitrii Fastovets, Roman Kruglikov, Anatoly Bobe, Anna Kamysheva, Ilya Krauz, Anastasiia Kilina, Pavel Ovcharov, Alexander Ryabyhk
  • Publication number: 20240161284
    Abstract: Techniques for processing multiplexed immunofluorescence (MxIF) images. The techniques include obtaining at least one MxIF image of a same tissue sample, obtaining information indicative of locations of cells in the at least one MxIF image, identifying multiple groups of cells in the at least one MxIF image at least in part by determining feature values for at least some of the cells using the at least one MxIF image and the information indicative of locations of the at least some cells in the at least one MxIF image and grouping the at least some of the cells into the multiple groups using the determined feature values, and determining at least one characteristic of the tissue sample using the multiple cell groups.
    Type: Application
    Filed: January 18, 2024
    Publication date: May 16, 2024
    Applicant: BostonGene Corporation
    Inventors: Viktor Svekolkin, Ilia Galkin, Ekaterina Postovalova, Ravshan Ataullakhanov, Alexander Bagaev, Arina Varlamova, Pavel Ovcharov
  • Patent number: 11915422
    Abstract: Techniques for processing multiplexed immunofluorescence (MxIF) images. The techniques include obtaining at least one MxIF image of a same tissue sample, obtaining information indicative of locations of cells in the at least one MxIF image, identifying multiple groups of cells in the at least one MxIF image at least in part by determining feature values for at least some of the cells using the at least one MxIF image and the information indicative of locations of the at least some cells in the at least one MxIF image and grouping the at least some of the cells into the multiple groups using the determined feature values, and determining at least one characteristic of the tissue sample using the multiple cell groups.
    Type: Grant
    Filed: December 27, 2021
    Date of Patent: February 27, 2024
    Assignee: BostonGene Corporation
    Inventors: Viktor Svekolkin, Ilia Galkin, Ekaterina Postovalova, Ravshan Ataullakhanov, Alexander Bagaev, Arina Varlamova, Pavel Ovcharov
  • Publication number: 20220122252
    Abstract: Techniques for processing multiplexed immunofluorescence (MxIF) images. The techniques include obtaining at least one MxIF image of a same tissue sample, obtaining information indicative of locations of cells in the at least one MxIF image, identifying multiple groups of cells in the at least one MxIF image at least in part by determining feature values for at least some of the cells using the at least one MxIF image and the information indicative of locations of the at least some cells in the at least one MxIF image and grouping the at least some of the cells into the multiple groups using the determined feature values, and determining at least one characteristic of the tissue sample using the multiple cell groups.
    Type: Application
    Filed: December 27, 2021
    Publication date: April 21, 2022
    Applicant: BostonGene Corporation
    Inventors: Viktor Svekolkin, Ilia Galkin, Ekaterina Postovalova, Ravshan Ataullakhanov, Alexander Bagaev, Arina Varlamova, Pavel Ovcharov
  • Patent number: 11250568
    Abstract: Techniques for processing multiplexed immunofluorescence (MxIF) images. The techniques include obtaining at least one MxIF image of a same tissue sample, obtaining information indicative of locations of cells in the at least one MxIF image, identifying multiple groups of cells in the at least one MxIF image at least in part by determining feature values for at least some of the cells using the at least one MxIF image and the information indicative of locations of the at least some cells in the at least one MxIF image and grouping the at least some of the cells into the multiple groups using the determined feature values, and determining at least one characteristic of the tissue sample using the multiple cell groups.
    Type: Grant
    Filed: March 6, 2021
    Date of Patent: February 15, 2022
    Assignee: BostonGene Corporation
    Inventors: Viktor Svekolkin, Ilia Galkin, Ekaterina Postovalova, Ravshan Ataullakhanov, Alexander Bagaev, Arina Varlamova, Pavel Ovcharov
  • Publication number: 20210279866
    Abstract: Techniques for processing multiplexed immunofluorescence (MxIF) images. The techniques include: obtaining at least one MxIF image of a same tissue sample; obtaining information indicative of locations of cells in the at least one MxIF image; identifying multiple groups of cells in the at least one MxIF image at least in part by: determining feature values for at least some of the cells using the at least one MxIF image and the information indicative of locations of the at least some cells in the at least one MxIF image; and grouping the at least some of the cells into the multiple groups using the determined feature values; and determining at least one characteristic of the tissue sample using the multiple cell groups.
    Type: Application
    Filed: March 6, 2021
    Publication date: September 9, 2021
    Inventors: Viktor Svekolkin, Ilia Galkin, Ekaterina Postovalova, Ravshan Ataullakhanov, Alexander Bagaev, Arina Varlamova, Pavel Ovcharov