Patents by Inventor Pavel Vanacek

Pavel Vanacek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thermostable FGF2 polypeptide, use thereof
    Patent number: 11746135
    Abstract: The invention provides an isolated thermostable polypeptide possessing FGF2 activity and having at least 85% sequence identity to SEQ ID NO: 2 (FGF2 wt) or a functional fragment thereof, and comprising at least one amino acid substitution R31L and the use thereof in the cell biology research, regenerative medicine and related medical applications or cosmetics. Further it discloses a culture medium comprising subjected FGF2 suitable for culturing a human pluripotent stem cells involving both human embryonic stem cells and induced pluripotent stem cells.
    Type: Grant
    Filed: October 3, 2016
    Date of Patent: September 5, 2023
    Assignees: Masarykova Univerzita, Enantis s.r.o.
    Inventors: Petr Dvorak, Pavel Krejci, Lukas Balek, Livia Eiselleova, Zaneta Konecna, Pavel Dvorak, David Bednar, Jan Brezovsky, Eva Sebestova, Radka Chaloupkova, Veronika Stepankova, Pavel Vanacek, Zbynek Prokop, Jiri Damborsky, Michaela Bosakova
  • Thermostable FGF2 Polypeptide, Use Thereof
    Publication number: 20200270320
    Abstract: The invention provides an isolated thermostable polypeptide possessing FGF2 activity and having at least 85% sequence identity to SEQ ID NO: 2 (FGF2 wt) or a functional fragment thereof, and comprising at least one amino acid substitution R31L and the use thereof in the cell biology research, regenerative medicine and related medical applications or cosmetics. Further it discloses a culture medium comprising subjected FGF2 suitable for culturing a human pluripotent stem cells involving both human embryonic stem cells and induced pluripotent stem cells.
    Type: Application
    Filed: October 3, 2016
    Publication date: August 27, 2020
    Inventors: Petr Dvorak, Pavel Krejci, Lukas Balek, Livia Eiselleova, Zaneta Konecna, Pavel Dvorak, David Bednar, Jan Brezovsky, Eva Sebestova, Radka Chaloupkova, Veronika Stepankova, Pavel Vanacek, Zbynek Prokop, Jiri Damborsky, Michaela Bosakova