Patents by Inventor Pavlos P. Vlachos

Pavlos P. Vlachos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11918661
    Abstract: The present disclosure relates to a novel nano-droplet composition comprising a fluorocarbon core and a polymeric shell, and the method of using and making the novel nano-droplet composition. The fluorocarbon core and the polymeric shell of the novel nano-droplet form a micelle with a size range of 10-1000 nm. The fluorocarbon core comprises at least one fluorocarbon compound with a formula of CnF2n+2 and n is 5-10. The fluorocarbon compound is substantial in liquid form. And the nano-droplet composition has a temperature profile such that the nano-droplet composition has a temperature range of 20-60° C. throughout a temperature modulation process, and has a temperature of about 37° C. prior to administration to a human, animal, biological cell, or tissue subject.
    Type: Grant
    Filed: July 22, 2020
    Date of Patent: March 5, 2024
    Assignee: Purdue Research Foundation
    Inventors: Pavlos P Vlachos, Anastasiia Vasiukhina, Luis Solorio
  • Patent number: 11810303
    Abstract: The present application relates to an automated segmentation method for use with echocardiograms (echo). The method uses an iterative Dijkstra's algorithm, a strategic node selection, and a novel cost matrix formulation based on intensity peak prominence and is this termed the “Prominence Iterative Dijkstra's” algorithm, or ProID.
    Type: Grant
    Filed: March 11, 2021
    Date of Patent: November 7, 2023
    Assignee: Purdue Research Foundation
    Inventors: Brett Albert Meyers, Pavlos P. Vlachos, Melissa Brindise
  • Patent number: 11763456
    Abstract: The present application includes a method and a software architecture for measuring global longitudinal strain (GLS) and global longitudinal strain rate (GLSr) from 2D echocardiograms. In contrast to conventional GLS computation methods, this approach does not require boundary segmentation and regularization.
    Type: Grant
    Filed: March 11, 2021
    Date of Patent: September 19, 2023
    Assignee: Purdue Research Foundation
    Inventors: Brett Albert Meyers, Pavlos P. Vlachos
  • Patent number: 11506783
    Abstract: A non-transitory computer-readable medium encoded with a computer-readable program, which, when executed by a processor, will cause a computer to execute a method of processing an image, wherein the method includes receiving a 2-D color Doppler image. The method additionally includes extracting a single component velocity field of a 2-D plane from the 2-D color Doppler image. Further, the method includes receiving a geometrical boundary of a region of interest within the 2-D color Doppler image. Moreover, the method includes applying a plurality of boundary conditions to the geometrical boundary, an at least one inlet, and an at least one outlet, of the single component velocity field of a 2-D plane. The method additionally includes solving a streamfunction vorticity formulation to reconstruct a transverse velocity component. Further, the method includes outputting a reconstructed 2-D 2-component velocity based on the transverse velocity component.
    Type: Grant
    Filed: March 4, 2019
    Date of Patent: November 22, 2022
    Assignee: Purdue Research Foundation
    Inventors: Carlo Scalo, Pavlos P Vlachos, Brett A Meyers
  • Publication number: 20210287371
    Abstract: The present application includes a method and a software architecture for measuring global longitudinal strain (GLS) and global longitudinal strain rate (GLSr) from 2D echocardiograms. In contrast to conventional GLS computation methods, this approach does not require boundary segmentation and regularization.
    Type: Application
    Filed: March 11, 2021
    Publication date: September 16, 2021
    Applicant: Purdue Research Foundation
    Inventors: Brett Albert Meyers, Pavlos P. Vlachos
  • Publication number: 20210287375
    Abstract: The present application relates to an automated segmentation method for use with echocardiograms (echo). The method uses an iterative Dijkstra's algorithm, a strategic node selection, and a novel cost matrix formulation based on intensity peak prominence and is this termed the “Prominence Iterative Dijkstra's” algorithm, or ProID.
    Type: Application
    Filed: March 11, 2021
    Publication date: September 16, 2021
    Applicant: Purdue Research Foundation
    Inventors: Brett Albert Meyers, Pavlos P. Vlachos, Melissa Brindise
  • Patent number: 11113815
    Abstract: Video processing methods and the associated system architecture for measuring transformation in objects, including pupils, entail the following steps: 1. Motion correction; 2. Object (eye) detection; 3. Image correction; and 4. Fourier-based analysis for item (in some embodiments the item is a pupil) motion estimation.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: September 7, 2021
    Assignee: Purdue Research Foundation
    Inventors: Pavlos P Vlachos, Brett Meyers
  • Publication number: 20210030898
    Abstract: The present disclosure relates to a novel nano-droplet composition comprising a fluorocarbon core and a polymeric shell, and the method of using and making the novel nano-droplet composition. The fluorocarbon core and the polymeric shell of the novel nano-droplet form a micelle with a size range of 10-1000 nm. The fluorocarbon core comprises at least one fluorocarbon compound with a formula of CnF2n+2 and n is 5-10. The fluorocarbon compound is substantial in liquid form. And the nano-droplet composition has a temperature profile such that the nano-droplet composition has a temperature range of 20-60° C. throughout a temperature modulation process, and has a temperature of about 37° C. prior to administration to a human, animal, biological cell, or tissue subject.
    Type: Application
    Filed: July 22, 2020
    Publication date: February 4, 2021
    Applicant: Purdue Research Foundation
    Inventors: Pavlos P. Vlachos, Anastasiia Vasiukhina, Luis Solorio
  • Publication number: 20200175686
    Abstract: Video processing methods and the associated system architecture for measuring transformation in objects, including pupils, entail the following steps: 1. Motion correction; 2. Object (eye) detection; 3. Image correction; and 4. Fourier-based analysis for item (in some embodiments the item is a pupil) motion estimation.
    Type: Application
    Filed: November 26, 2019
    Publication date: June 4, 2020
    Applicant: Purdue Research Foundation
    Inventors: Pavlos P. Vlachos, Meyers Brett
  • Publication number: 20190277965
    Abstract: A non-transitory computer-readable medium encoded with a computer-readable program, which, when executed by a processor, will cause a computer to execute a method of processing an image, wherein the method includes receiving a 2-D color Doppler image. The method additionally includes extracting a single component velocity field of a 2-D plane from the 2-D color Doppler image. Further, the method includes receiving a geometrical boundary of a region of interest within the 2-D color Doppler image. Moreover, the method includes applying a plurality of boundary conditions to the geometrical boundary, an at least one inlet, and an at least one outlet, of the single component velocity field of a 2-D plane. The method additionally includes solving a streamfunction vorticity formulation to reconstruct a transverse velocity component. Further, the method includes outputting a reconstructed 2-D 2-component velocity based on the transverse velocity component.
    Type: Application
    Filed: March 4, 2019
    Publication date: September 12, 2019
    Applicant: Purdue Research Foundation
    Inventors: Carlo Scalo, Pavlos P. Vlachos, Brett A. Meyers