Patents by Inventor Paw Bloch

Paw Bloch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SEMI-RECOMBINANT PREPARATION OF GLP-1 ANALOGUES
    Publication number: 20100317057
    Abstract: A semi-recombinant method for the production of GLP-1 analogues and derivatives with non-proteogenic amino acids in the N-terminal part combining the use of recombinant expression techniques and chemical peptide synthesis.
    Type: Application
    Filed: December 22, 2007
    Publication date: December 16, 2010
    Applicant: NOVO NORDISK A/S
    Inventors: Jesper Faergeman Lau, Asser Sloth Andersen, Paw Bloch, Jesper Lau, Patrick William Garibay, Thomas Kruse, Inga Sig Nielsen Nørby, Claus Ulrich Jessen, Caspar Christensen, Jens Christian Norrild
  • Novel GLP-1 Derivatives
    Publication number: 20100305032
    Abstract: Novel polypeptide derivatives having protracted profile of action.
    Type: Application
    Filed: May 5, 2010
    Publication date: December 2, 2010
    Applicant: Novo Nordisk A/S
    Inventors: Jesper Lau, Thomas Kruse Hansen, Kjeld Madsen, Paw Bloch, Florencio Zaragoza Dorwald, Nils Langeland Johansen
  • Synthesis and Application of New Structural Well Defined Branched Polymers as Conjugating Agents for Peptides
    Publication number: 20090240028
    Abstract: The invention provides synthesis and application of new structural well defined branched polymers as protraction agents for peptide and protein.
    Type: Application
    Filed: November 24, 2008
    Publication date: September 24, 2009
    Applicant: Novo Nordisk A/S
    Inventors: Carsten Behrens, Florencio Zaragoza Dorwald, Mikael Kofod-Hansen, Jesper Lau, Janos Tibor Kodra, Thomas Kruse Hansen, Paw Bloch
  • Acylated GLP-1 Compounds
    Publication number: 20090156478
    Abstract: Protracted GLP-1 compounds and therapeutic uses thereof.
    Type: Application
    Filed: March 20, 2006
    Publication date: June 18, 2009
    Applicant: Novo Nordisk A/S
    Inventors: Jesper Lau, Florencio Zaragoza Dorwald, Henrik Stephensen, Paw Bloch, Thomas Kruse Hansen, Kjeld Madsen
  • Aryl carbonyl derivatives as therapeutic agents
    Patent number: 7541373
    Abstract: This invention relates to aryl carbonyl derivatives which are activators of glucokinase which may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial.
    Type: Grant
    Filed: March 1, 2006
    Date of Patent: June 2, 2009
    Assignee: Novo Nordisk A/S
    Inventors: Dharma Rao Polisetti, Janos Tibor Kodra, Jesper Lau, Paw Bloch, Mustafa Guzel, Kalpathy Chidambareswaran Santhosh, Adnan M. M. Mjalli, Robert Carl Andrews, Govindan Subramanian, Michael Ankersen, Per Vedso, Anthony Murray, Lone Jeppesen, Jesper Lau
  • Aryl carbonyl derivatives as therapeutic agents
    Patent number: 7384967
    Abstract: This invention relates to aryl carbonyl derivatives which are activators of glucokinase which may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial.
    Type: Grant
    Filed: October 6, 2003
    Date of Patent: June 10, 2008
    Assignee: Novo Nordisk A/S
    Inventors: Dharma Rao Polisetti, Janos Tibor Kodra, Jesper Lau, Paw Bloch, Mustafa Guzel, Kalpathy Chidambareswaran Santhosh, Adnan M. M. Mjalli, Robert Carl Andrews, Govindan Subramanian, Michael Ankersen, Per Vedso, Anthony Murray, Lone Jeppesen
  • Aryl carbonyl derivatives as therapeutic agents
    Publication number: 20080119455
    Abstract: This invention relates to aryl carbonyl derivatives which are activators of glucokinase which may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial.
    Type: Application
    Filed: October 31, 2007
    Publication date: May 22, 2008
    Applicant: Novo Nordisk A/S
    Inventors: Dharma Polisetti, Janos Kodra, Jesper Lau, Paw Bloch, Maria Valcarce-Lopez, Niels Blume, Mustafa Guzel, Kalpathy Santhosh, Adnan Mjalli, Robert Andrews, Govindan Subramanian, Michael Ankersen, Per Vedso, Anthony Murray, Lone Jeppesen
  • Aryl carbonyl derivatives as therapeutic agents
    Publication number: 20080119454
    Abstract: This invention relates to aryl carbonyl derivatives which are activators of glucokinase which may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial.
    Type: Application
    Filed: October 31, 2007
    Publication date: May 22, 2008
    Applicant: Novo Nordisk A/S
    Inventors: Dharma Polisetti, Janos Kodra, Jesper Lau, Paw Bloch, Maria Valcarce-Lopez, Niels Blume, Mustafa Guzel, Kalpathy Santhosh, Adnan Mjalli, Robert Andrews, Govindan Subramanian, Michael Ankersen, Per Vedso, Anthony Murray, Lone Jeppesen
  • Novel Glp-1 Derivatives
    Publication number: 20070203058
    Abstract: Novel polypeptide derivatives having protracted profile of action. The present invention relates to a compound which comprises a therapeutic polypeptide linked to an albumin binding residue via a hydrophilic spacer. The present invention also relates to a compound which comprises a therapeutic polypeptide linked to an albumin binding residue via a hydrophilic spacer that separates the polypeptide and the albumin binding residue with a chemical moiety comprising at least 5 non-hydrogen atoms where 30-50% of these atoms are either N or O.
    Type: Application
    Filed: September 17, 2004
    Publication date: August 30, 2007
    Applicant: NOVO NORDISK A/S
    Inventors: Jesper Lau, Thomas Hansen, Kjeld Madsen, Paw Bloch, Florencio Dorwald, Nils Johansen
  • Aryl carbonyl derivatives as therapeutic agents
    Publication number: 20060183783
    Abstract: This invention relates to aryl carbonyl derivativeswhich are activators of glucokinase which may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial.
    Type: Application
    Filed: March 1, 2006
    Publication date: August 17, 2006
    Inventors: Dharma Polisetti, Janos Kodra, Jesper Lau, Paw Bloch, Maria Lopez, Niels Blume, Mustafa Guzel, Kalpathy Santhosh, Adnan Mjalli, Robert Andrews, Govindan Subramanian, Michael Ankersen, Per Vedso, Anthony Murray, Lone Jeppesen
  • Synthesis and application of new structural well defined branched polymers as conjugating agents for peptides
    Publication number: 20060182714
    Abstract: The invention provides synthesis and application of new structural well defined branched polymers as protraction agents for peptide and protein.
    Type: Application
    Filed: February 1, 2006
    Publication date: August 17, 2006
    Applicant: Novo Nordisk A/S
    Inventors: Carsten Behrens, Florencio Dorwald, Mikael Kofod-Hansen, Jesper Lau, Janos Kodra, Thomas Hansen, Paw Bloch
  • Novel glucagon antagonists/inverse agonists
    Publication number: 20050256175
    Abstract: Novel compounds that act to antagonize the action of the glucagon peptide hormone on the glucagon receptor. More particularly, it relates to glucagon antagonists or inverse agonists.
    Type: Application
    Filed: February 22, 2005
    Publication date: November 17, 2005
    Inventors: Jesper Lau, Inger Christensen, Peter Madsen, Paw Bloch, Carsten Behrens, Janos Kodra, Poul Nielsen
  • Glucagon antagonists/inverse agonists
    Patent number: 6881746
    Abstract: Novel compounds that act to antagonize the action of the glucagon peptide hormone on the glucagon receptor. More particularly, it relates to glucagon antagonists or inverse agonists.
    Type: Grant
    Filed: May 30, 2003
    Date of Patent: April 19, 2005
    Assignee: Novo Nordick A/S
    Inventors: Jesper Lau, Inge Thoger Christensen, Peter Madsen, Paw Bloch, Carsten Behrens, Janos Tibor Kodra, Poul Enrico Nielsen
  • Aryl carbonyl derivatives as therapeutic agents
    Publication number: 20040122235
    Abstract: This invention relates to aryl carbonyl derivatives which are activators of glucokinase which may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial.
    Type: Application
    Filed: October 6, 2003
    Publication date: June 24, 2004
    Inventors: Dharma Rao Polisetti, Janos Tibor Kodra, Jesper Lau, Paw Bloch, Maria Carmen Valcarce-Lopez, Niels Blume, Mustafa Guzel, Kalpathy Chidambareswaran Santhosh, Adnan M.M. Mjalli, Robert Carl Andrews, Govindan Subramanian, Michael Ankersen, Per Vedso, Anthony Murray, Lone Jeppesen
  • Novel glucagon antagonists/inverse agonists
    Publication number: 20040014789
    Abstract: Novel compounds that act to antagonize the action of the glucagon peptide hormone on the glucagon receptor. More particularly, it relates to glucagon antagonists or inverse agonists.
    Type: Application
    Filed: May 30, 2003
    Publication date: January 22, 2004
    Inventors: Jesper Lau, Inge Thoger Christensen, Peter Madsen, Paw Bloch, Carsten Behrens, Janos Tibor Kodra, Poul Enrico Nielsen