Patents by Inventor Pawel Pyc

Pawel Pyc has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR PREPARATION OF TADALAFIL
    Publication number: 20110124866
    Abstract: Process for the preparation of tadalafil of high pharmaceutical purity is characterized in that the sequence of reactions comprising acetylation of methyl (1R,3R)-1-(1,3-benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate with chloro acetyl chloride and cyclisation of the formed intermediate with methyl amine, is performed as a ‘one-pot’ process, without isolating the intermediate methyl (1R,3R)-1-(1,3-benzodioxol-5-yl)-2-(chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate.
    Type: Application
    Filed: June 3, 2009
    Publication date: May 26, 2011
    Applicant: Zaklady Famaceutyczne Polpharma SA
    Inventors: Lukasz Kaczmarek, Pawel Pyc, Katarzyna Badowska-Roslonek