Abstract: Disclosed is a microfluidic circuit, microfluidic chip, kit and method for isolating and purifying an analyte, preferably a nucleic acid.

Abstract: The invention relates to an explosion-protected housing for means for transmitting and/or receiving electromagnetic radiation. The housing comprises a housing body that is configured to receive such transmission and/or reception means and a window element having a first side that faces the housing interior and an opposite second side that faces away from the housing interior, wherein the window element transmits electromagnetic radiation. The housing body has a flanging on the second side of the window element, said flanging pressing the window element in the direction of a seat that is formed in the interior of the housing such that the housing is formed as a pressure-resistant housing and/or as a dust-tight housing.

Abstract: The invention relates to an explosion-protected housing for means for transmitting and/or receiving electromagnetic radiation (2, 2a, 2b). The housing comprises a housing body (1) that is configured to receive such transmission and/or reception means (2, 2a, 2b) and a window element (5) having a first side (7) that faces the housing interior and an opposite second side (6) that faces away from the housing interior, wherein the window element (5) transmits electromagnetic radiation. The housing body (1) has a flanging (11) on the second side (6) of the window element (5), said flanging pressing the window element (5) in the direction of a seat (13) that is formed in the interior of the housing such that the housing is formed as a pressure-resistant housing and/or as a dust-tight housing.

Abstract: The present invention is directed to isolated peptides, compositions comprising same and methods of use thereof for treating tumors infiltrated with macrophages, such as glioblastomas.

Abstract: A drug eluting guide wire comprises a body aperture having low friction characteristics. The guide wire includes an effective leading end segment that is formed along its outer surface with a rapid action body aperture drug eluting agent serving as a vasilodating substance. The low friction characteristics are achieved by the leading end segment of the wire being covered with a low friction lubricating substance such as hydrogel that is loaded with a drug eluting substance in the form of isoprenaline in constituting the segment. Isoprenaline serves a constricted body aperture rapid action relaxing function in amongst others, or at least the case of the guide wire, is used to access a kidney along a ureter in response to temporarily paralyzing the smooth muscles of the ureteric wall resulting in widening of the lumen of the ureter.

Abstract: An organ flush and drainage unit for limiting an increase of pressure within a cavity of an organ during liquid irrigation is disclosed. The unit comprises a drainage body enclosing a drainage zone in the form of a drainage chamber as encompassed within a unit wall. The unit also includes a coupling passage in the form of a mouth defined at the opened up end of the chamber. The unit further includes an instrument insertion aperture that is in alignment with the mouth and that is formed with a penetrable sealing means by being fitted with a membrane type penetrable resilient sealing member defining a central location of instrument penetration along which an organ working instrument which is sealably insertable and a drainage cum charging location in the form of a drainage cum charging stub extending from the chamber though the wall of the unit.

Abstract: This invention relates to a fluid collecting system for collecting fluid downstream from a patient via a fluid collection line. The system comprises a fluid collecting bag (12) and an overflow device (14). The bag comprises an inlet tube (20) connectable to a bladder of a patient and to the interior of the bag (18), and an overflow tube (26) connected to the inlet tube (20) adjacent a top of the bag (12) and to an optional overflow device (14) to drain the bag if overflow occurs, in use. The overflow device (14) comprises a housing (30) having chamber (32), an inlet port (34) to the chamber connectable to the overflow tube (26), and a resiliently flexible member (36) located in the chamber. The member (36) is displaceable between a storage configuration, in which the overflow member is located in the chamber (32), and a filling configuration, in which the overflow member (36) extends from the chamber with fluid received from the overflow tube (26) held therein.

Abstract: A modular multi-sensor fire detector (300) that has an evaluation unit and a plurality of sensor heads (100) which are arranged locally at a distance from the evaluation unit and are connected to the evaluation unit in a signal-conducting manner, wherein the evaluation unit (200) can be connected in a signal-conducting manner to an alarm signal receiving device (301) which is locally at a distance.

Abstract: The invention relates to a hazard detector for an evaluation unit (12, 14), e.g. a fire detector and/or extinguishing control center (12). The hazard detector (10) comprises a housing (16) having at least one sensor unit (22) or a sensor interface for connecting the sensor unit (22) to capture a hazard parameter. Moreover, the hazard detector (10) comprises a first electronic assembly (26), electrically connected to the sensor unit (22) or the sensor interface, for processing sensor signals of the sensor unit (22), and a second electronic assembly (30), connected to at least one first interface (38) for electrically connecting the second electrical assembly (30) to a physically remote evaluation unit (12, 14). In this arrangement, the first electronic assembly (26) and the second electronic assembly (30) comprise a wireless data connection (32) for transmitting the processed sensor signals from at least the first electronic assembly (26) to the second electronic assembly (30).

Abstract: The invention relates to a hazard detector for an evaluation unit (12, 14), e.g. a fire detector and/or extinguishing control center (12). The hazard detector (10) comprises a housing (16) having at least one sensor unit (22) or a sensor interface for connecting the sensor unit (22) to capture a hazard parameter. Moreover, the hazard detector (10) comprises a first electronic assembly (26), electrically connected to the sensor unit (22) or the sensor interface, for processing sensor signals of the sensor unit (22), and a second electronic assembly (30), connected to at least one first interface (38) for electrically connecting the second electrical assembly (30) to a physically remote evaluation unit (12, 14). In this arrangement, the first electronic assembly (26) and the second electronic assembly (30) comprise a wireless data connection (32) for transmitting the processed sensor signals from at least the first electronic assembly (26) to the second electronic assembly (30).

Abstract: The invention relates to a modular multi-sensor fire detector (300). The invention proposes that the detector (300) has an evaluation unit and a plurality of sensor heads (100) which are arranged locally at a distance from the evaluation unit and are connected to the evaluation unit in a signal-conducting manner, wherein the evaluation unit (200) can be connected in a signal-conducting manner to an alarm signal receiving device (301) which is locally at a distance. The invention also relates to a fire detection system having such a detector.

Abstract: This invention relates to a fluid collecting system for collecting fluid downstream from a patient via a fluid collection line. The system comprises a fluid collecting bag (12) and an overflow device (14). The bag comprises an inlet tube (20) connectable to a bladder of a patient and to the interior of the bag (18), and an overflow tube (26) connected to the inlet tube (20) adjacent a top of the bag (12) and to an optional overflow device (14) to drain the bag if overflow occurs, in use. The overflow device (14) comprises a housing (30) having chamber (32), an inlet port (34) to the chamber connectable to the overflow tube (26), and a resiliently flexible member (36) located in the chamber. The member (36) is displaceable between a storage configuration, in which the overflow member is located in the chamber (32), and a filling configuration, in which the overflow member (36) extends from the chamber with fluid received from the overflow tube (26) held therein.

Abstract: This invention relates to a fluid collecting system for collecting fluid downstream from a patient via a fluid collection line. The system comprises a fluid collecting bag (12) and an overflow device (14). The bag comprises an inlet tube (20) connectable to a bladder of a patient and to the interior of the bag (18), and an overflow tube (26) connected to the inlet tube (20) adjacent a top of the bag (12) and to an optional overflow device (14) to drain the bag if overflow occurs, in use. The overflow device (14) comprises a housing (30) having chamber (32), an inlet port (34) to the chamber connectable to the overflow tube (26), and a resiliently flexible member (36) located in the chamber. The member (36) is displaceable between a storage configuration, in which the overflow member is located in the chamber (32), and a filling configuration, in which the overflow member (36) extends from the chamber with fluid received from the overflow tube (26) held therein.

Abstract: Isolated peptides, compositions and methods of use for treating tumors infiltrated with macrophages, such as glioblastomas.

Abstract: Filtered heat and moisture exchange device for a breathing system comprises a housing (40) having first and second ports (42,46) connectable to breathing lines (20,22) and a chamber (50) being located between and in flow communication with the ports. An air filter (52) and a heat and moisture exchange means (54) are located in the chamber (50). A tubular gas sampling member (64) is extending from gas sampling port (56) located near the first port (42) to a sampling location (B) in the second port (46) by passing chamber (50) and central apertures of air filter (52) and heat and moisture exchange means (54).

Abstract: Isolated peptides, compositions and methods of use for treating tumors infiltrated with macrophages, such as glioblastomas.

Abstract: Isolated peptides, compositions and methods of use for treating tumors infiltrated with macrophages, such as glioblastomas.

Abstract: Breathing equipment (10) for use in conventional operating room procedures comprises a flexible breathing bag (12) connected at one end (12.1) via a gas redirecting connector (14) to a gas guiding tube (16) and at the opposite end to a flexible exhaust gas bridging tube (18) forming part of a gas removal conduit (20) used for the remote venting of exhaled gas via a remote discharge tube (22) also forming part of the conduit (20). A breathing piece (28) is situated at the free end of the tube (16). An inhalation gas supply tube (24) passes within the tube (22) and via the connector (14) into the gas guiding tube (16) up to a position of discharge in close proximity of a user. The connector (14) is formed to cause exhaled gases from the piece (28) to pass along the tube (16) and through the bag (12) prior to remote venting to enable use of the ‘feel’ of the bag (12) during breathing assistance.

Abstract: A hand held fluid manipulator in the form of a suction device 10 comprises circumferentially enclosed reopenably closable fluid transfer path defining means as constituted from a displaceably mounted tube 14, a flow path defining section 16, a nozzle carrying tube and a chamber 32 defining in combination a reopenably closeable fluid transfer path 20. The device also comprises a handle 22 and a flexible strip 24 that engages with the tube 14 by way of a tube displacer formation 26. The strip 24 is lockable in a fluid transfer path open condition by way of a hook 30. The chamber 32 is open to the tube 14 by way of a set of apertures 34. Opening an closing of the fluid transfer path 20 is regulated by a fluid flow regulating arrangement 36 as constituted by the chamber 32 and the aperture set 34 and blocking of the inner end 14.2 of the tube 14.

Abstract: Breathing equipment (10) for use in conventional operating room procedures comprises a flexible breathing bag (12) connected at one end (12.1) via a gas redirecting connector (14) to a gas guiding tube (16) and at the opposite end to a flexible exhaust gas bridging tube (18) forming part of a gas removal conduit (20) used for the remote venting of exhaled gas via a remote discharge tube (22) also forming part of the conduit (20). A breathing piece (28) is situated at the free end of the tube (16). An inhalation gas supply tube (24) passes within the tube (22) and via the connector (14) into the gas guiding tube (16) up to a position of discharge in close proximity of a user. The connector (14) is formed to cause exhaled gases from the piece (28) to pass along the tube (16) and through the bag (12) prior to remote venting to enable use of the ‘feel’ of the bag (12) during breathing assistance.