Abstract: An ablation apparatus for creating a lesion in target tissue has a handle, an elongate shaft extending from the handle and a distal ablation portion. The distal ablation portion includes a cryogen flow manifold defining a plurality of fluid pathways between an insert body and a sleeve. Cryogen is circulated through the plurality of fluid pathways to create the lesion in the target tissue.

Abstract: A multimodality or hybrid ablation system includes an ablation apparatus for creating a lesion in target tissue. The ablation apparatus has an ablation shaft including a handle, a first portion, an ablation portion, distal tip, at least one ablation energy delivery lumen, at least one ablation energy return lumen, and a stylet lumen that extends substantially along a length of the ablation shaft from the handle to at least the ablation portion. The ablation apparatus also includes a stylet that is capable of being inserted into the stylet lumen where the stylet is made of a shape-memory material. A plurality of electrodes are arranged on the ablation portion for measuring or verifying tissue contact with the tissue and applying a pulsed electric field. Optionally, the pulsed electric field may be applied after or in parallel with freezing the target tissue.

Abstract: An ablation apparatus for creating a lesion in target tissue, the ablation apparatus having an ablation shaft including a handle, a first portion, an ablation portion, distal tip, at least one ablation energy delivery lumen, at least one ablation energy return lumen, and a stylet lumen that extends substantially along a length of the ablation shaft from the handle to at least the ablation portion. The ablation apparatus also includes a stylet that is capable of being inserted into the stylet lumen where the stylet is made of a shape-memory material.

Abstract: An ablation apparatus for creating a lesion in target tissue, the ablation apparatus having an ablation shaft including a handle, a first portion, an ablation portion, distal tip, at least one ablation energy delivery lumen, at least one ablation energy return lumen, and a stylet lumen that extends substantially along a length of the ablation shaft from the handle to at least the ablation portion. The ablation apparatus also includes a stylet that is capable of being inserted into the stylet lumen where the stylet is made of a shape-memory material.

Abstract: A multimodality or hybrid ablation system includes an ablation apparatus for creating a lesion in target tissue. The ablation apparatus has an ablation shaft including a handle, a first portion, an ablation portion, distal tip, at least one ablation energy delivery lumen, at least one ablation energy return lumen, and a stylet lumen that extends substantially along a length of the ablation shaft from the handle to at least the ablation portion. The ablation apparatus also includes a stylet that is capable of being inserted into the stylet lumen where the stylet is made of a shape-memory material. A plurality of electrodes are arranged on the ablation portion for measuring or verifying tissue contact with the tissue and applying a pulsed electric field. Optionally, the pulsed electric field may be applied after, contemporaneously, or for only a portion that the cryo-modality is applied to the target tissue.

Abstract: An ablation apparatus for creating a lesion in target tissue has a handle, an elongate shaft extending from the handle and a distal ablation portion. The distal ablation portion includes a cryogen flow manifold defining a plurality of fluid pathways between an insert body and a sleeve. Cryogen is circulated through the plurality of fluid pathways to create the lesion in the target tissue.

Abstract: An ablation apparatus for creating a lesion in target tissue, the ablation apparatus having an ablation shaft including a handle, a first portion, an ablation portion, distal tip, at least one ablation energy delivery lumen, at least one ablation energy return lumen, and a stylet lumen that extends substantially along a length of the ablation shaft from the handle to at least the ablation portion. The ablation apparatus also includes a stylet that is capable of being inserted into the stylet lumen where the stylet is made of a shape-memory material.

Abstract: Various tools and procedures are provided for implantation of an implant at a target site. The procedure can include performing an osteotomy at the target site; placing a guide sleeve into the osteotomy; inserting a coring tool into the guide sleeve; coring the target site up to a depth less than the depth of the osteotomy, the coring tool being configured to collect autogenous bone material from the target site during the coring of the target site; placing the implant at the implant site; and grafting the autogenous bone material into selected portions of the target site.

Abstract: Stent graft delivery systems are disclosed herein. In several embodiments, a stent graft delivery system can include a stent graft having a proximal portion and a distal portion, a proximal sheath and a distal sheath. The proximal sheath can be configured to cover the proximal portion of the stent graft, and the distal sheath can be configured to cover the distal portion of the stent graft. The proximal sheath and the distal sheath can be independently removable from respective ends of the stent graft such that the proximal and distal portions of the stent graft are independently deployable.

Abstract: Stent graft delivery systems are disclosed herein. In several embodiments, a stent graft delivery system can include a stent graft having a proximal portion and a distal portion, a proximal sheath and a distal sheath. The proximal sheath can be configured to cover the proximal portion of the stent graft, and the distal sheath can be configured to cover the distal portion of the stent graft. The proximal sheath and the distal sheath can be independently removable from respective ends of the stent graft such that the proximal and distal portions of the stent graft are independently deployable.

Abstract: Stent graft delivery systems are disclosed herein. In several embodiments, a stent graft delivery system can include a stent graft having a proximal portion and a distal portion, a proximal sheath and a distal sheath. The proximal sheath can be configured to cover the proximal portion of the stent graft, and the distal sheath can be configured to cover the distal portion of the stent graft. The proximal sheath and the distal sheath can be independently removable from respective ends of the stent graft such that the proximal and distal portions of the stent graft are independently deployable.