Patents by Inventor Pedro A. Carrillo

Pedro A. Carrillo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polypeptide fusions to polypeptides of the beta-trefoil fold structural family
    Patent number: 5830706
    Abstract: The invention is directed to the use of IL-1-like fusion polypeptides to increase the solubility and activity of recombinant polypeptides. The invention includes a nucleic acid encoding a fusion polypeptide comprising an interleukin-1-like polypeptide and a polypeptide of interest and the method of using such a nucleic acid to produce recombinant fusion polypeptides.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: November 3, 1998
    Assignee: Celtrix Pharmaceuticals, Inc.
    Inventors: Desmond Mascarenhas, Yang Zhang, Pamela S. Olson, David R. Olsen, Pedro A. Carrillo
  • Uses of TGF-.beta. receptor fragment as a therapeutic agent
    Patent number: 5693607
    Abstract: A method of treating TGF-.beta. excess is disclosed. The treatment is parenteral, oral or topical administration of TGF-.beta. receptor fragment. Particularly effective is a soluble receptor fragment which resembles the extracellular portion of TGF-.beta. binding protein II.
    Type: Grant
    Filed: December 22, 1994
    Date of Patent: December 2, 1997
    Inventors: Patricia R. Segarini, James R. Dasch, David R. Olsen, Pedro A. Carrillo, Desmond Mascarenhas
  • Fusion polypeptides and proteins
    Patent number: 5563046
    Abstract: The invention is directed to the use of IL-1-like fusion polypeptides to increase the solubility and activity of recombinant polypeptides. The invention includes a nucleic acid encoding a fusion polypeptide comprising an interleukin-1-like polypeptide and a polypeptide of interest and the method of using such a nucleic acid to produce recombinant fusion polypeptides.
    Type: Grant
    Filed: August 2, 1993
    Date of Patent: October 8, 1996
    Assignee: Celtrix Pharmaceuticals, Inc.
    Inventors: Desmond Mascarenhas, Yang Zhang, Pamela S. Olson, David R. Olsen, Pedro A. Carrillo