Patents by Inventor Pedro BESADA PEREIRA

Pedro BESADA PEREIRA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of pharmacological chaperones for the treatment of lysosomal storage diseases
    Patent number: 11192874
    Abstract: The present invention relates to the use of galactose analogues of formula (I) with the capacity to stabilize the structure of the #-GalA enzyme, for the treatment of lysosomal storage diseases and, in a preferred embodiment, for the treatment of Fabry disease. In addition, the present invention relates to pharmacological compositions having an effective amount of at least one of the galactose analogues described in the present document for the treatment of lysosomal storage diseases and, in a preferred embodiment, for the treatment of Fabry disease.
    Type: Grant
    Filed: December 10, 2018
    Date of Patent: December 7, 2021
    Assignees: FUNDACION BIOMEDICA GALICIA SUR, UNIVERSIDAD DE VIGO
    Inventors: Saida Ortolano, Pedro Besada Pereira, Carmen Teran Moldes
  • USE OF PHARMACOLOGICAL CHAPERONES FOR THE TREATMENT OF LYSOSOMAL STORAGE DISEASES
    Publication number: 20210179575
    Abstract: The present invention relates to the use of galactose analogues of formula (I) with the capacity to stabilize the structure of the #-GalA enzyme, for the treatment of lysosomal storage diseases and, in a preferred embodiment, for the treatment of Fabry disease. In addition, the present invention relates to pharmacological compositions having an effective amount of at least one of the galactose analogues described in the present document for the treatment of lysosomal storage diseases and, in a preferred embodiment, for the treatment of Fabry disease.
    Type: Application
    Filed: December 10, 2018
    Publication date: June 17, 2021
    Inventors: Saida ORTOLANO, Pedro BESADA PEREIRA, Carmen TERAN MOLDES
  • Pyridazin-3(2H)-one derivatives as monoamine oxidase selective isoform B inhibitors
    Patent number: 10253000
    Abstract: The present invention refers to pyridazin-3(2H)-one derivatives of general structure I, II and III, which are selective MAO-B inhibitors, and to the use thereof for preparing medicaments intended to treat disorders derived from MAO-B hyperactivity, particularly degenerative disorders of the central nervous system (CNS), such as Parkinson's disease (PD), Alzheimer's disease (AD) and other dementias. These are pyridazin-3(2H)-one derivatives having dithiocarbamate moieties bonded to position 4, 5 or 6 through an alkyl chain of variable length (n=1, 2, 3). This invention is also directed to the preparation of said compounds.
    Type: Grant
    Filed: March 3, 2015
    Date of Patent: April 9, 2019
    Assignees: UNIVERSIDADE DE VIGO, UNIVERSIDADE DE SANTIAGO DE COMPOSTELA
    Inventors: Ma del Carmen Terán Moldes, Pedro Besada Pereira, Tamara Costas Caamaño, Ma del Carmen Costas Lago, Noemí Vila Molares, Dolores Viña Castelao
  • PYRIDAZIN-3(2H)-ONE DERIVATIVES AS MONOAMINE OXIDASE SELECTIVE ISOFORM B INHIBITORS (As Amended)
    Publication number: 20180215718
    Abstract: The present invention refers to pyridazin-3(2H)-one derivatives of general structure I, II and III, which are selective MAO-B inhibitors, and to the use thereof for preparing medicaments intended to treat disorders derived from MAO-B hyperactivity, particularly degenerative disorders of the central nervous system (CNS), such as Parkinson's disease (PD), Alzheimer's disease (AD) and other dementias. These are pyridazin-3(2H)-one derivatives having dithiocarbamate moieties bonded to position 4, 5 or 6 through an alkyl chain of variable length (n=1, 2, 3). This invention is also directed to the preparation of said compounds.
    Type: Application
    Filed: March 3, 2015
    Publication date: August 2, 2018
    Applicants: UNIVERSIDADE DE VIGO, UNIVERSIDADE DE SANTIAGO DE COMPOSTELA
    Inventors: Mª del Carmen TERÁN MOLDES, Pedro BESADA PEREIRA, Tamara COSTAS CAAMAÑO, Mª del Carmen COSTAS LAGO, Noemí VILA MOLARES, Dolores VIÑA CASTELAO