Patents by Inventor Pedro CLAPÉS SABORIT

Pedro CLAPÉS SABORIT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fatty acid amides for the prevention and/or treatment of steatohepatitis
    Patent number: 11058650
    Abstract: The invention relates to the use of fatty acid amides with phenylalkylamines and of a pharmaceutical composition comprising at least one of these compounds in the prevention and/or treatment of fatty liver or a pathological condition or disease caused by fatty liver, either alcoholic or non-alcoholic, and, in particular, for the prevention and/or treatment of the alcoholic steatohepatitis or non-alcoholic steatohepatitis (NASH).
    Type: Grant
    Filed: November 24, 2015
    Date of Patent: July 13, 2021
    Assignees: FUNDACIÓN PÚBLICA ANDALUZA PARA LA INVESTIGACIÓN DE MÁLAGA EN BIOMEDICINA Y SALUD (FIMABIS), CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC), FUNDACIÓ INSTITUT MAR DTNVESTIGACIONS MÈDIOUES
    Inventors: Fernando Rodríguez De Fonseca, Francisco Javier Pavón Morón, Juan Manuel Decara Del Olmo, Antonia Serrano Criado, Jesús Joglar Tamargo, Pedro Clapés Saborit, Rafael De La Torre Fornell, Magí Ferre Albaladejo, María Isabel Covas Planells, Montserrat Fito Colomer, Bruno Almeida Cotrim
  • Fusion proteins comprising an aldolase enzyme joined to a maltose binding protein
    Patent number: 10683493
    Abstract: The present invention refers to an enzyme consisting of a fusion protein particularly useful as shown through-out the present invention for carrying out the carbon-carbon bond-forming reaction known as the aldol Reaction, preferably for carrying out an aldol reaction by using aldehydes as substrates and preferably pyruvate or a salt thereof, for producing hydroxyketoacids. Said enzyme is made by binding an aldolase to a maltose binding protein. The enzymes display full activity under “highly denaturing” substrate loadings (aldehydes, >1 M).
    Type: Grant
    Filed: May 17, 2017
    Date of Patent: June 16, 2020
    Assignees: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS, TECHNICAL UNIVERSITY OF DARMSTADT, SUSTAINABLE MOMENTUM, S.L.
    Inventors: Pedro Clapés Saborit, Karel Hernández Sánchez, Jesús Joglar Tamargo, Jordi Bujons Vilás, Wolf-Dieter Fessner, Pablo Domínguez De María
  • FRUCTOSE-6-PHOSPHATE ALDOLASE VARIANTS FOR ALDOL CARBOLIGATIONS
    Publication number: 20200165640
    Abstract: The invention provides new and alternative fructose-6-phosphate aldolase (FSA) variants which enable the production of optically active building blocks with high chemoselectivity and stereoselectivity using aldehydes as starting material in aldol carboligation reactions, while avoiding the by-product formation and subsequent reactions.
    Type: Application
    Filed: April 5, 2018
    Publication date: May 28, 2020
    Inventors: Pedro CLAPÉS SABORIT, Jesus JOGLAR TAMARGO, Jorge BUJONS VILAS, Raque! ROLDAN GARCIA, Wolf-Dieter FESSNER, Sebastian JUNKER, Pabio DOMINGUEZ DE MARIA
  • FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN
    Publication number: 20190194638
    Abstract: The present invention refers to an enzyme consisting of a fusion protein particularly useful as shown through-out the present invention for carrying out the carbon-carbon bond-forming reaction known as the aldol Reaction, preferably for carrying out an aldol reaction by using aldehydes as substrates and preferably pyruvate or a salt thereof, for producing hydroxyketoacids. Said enzyme is made by binding an aldolase to a maltose binding protein. The enzymes display full activity under “highly denaturing” substrate loadings (aldehydes, >1 M).
    Type: Application
    Filed: May 17, 2017
    Publication date: June 27, 2019
    Inventors: Pedro CLAPÉS SABORIT, Karel HERNÁNDEZ SÁNCHEZ, Jesús JOGLAR TAMARGO, Jordi BUJONS VILÁS, Wolf-Dieter FESSNER, Pablo DOMÍNGUEZ DE MARÍA
  • FATTY ACID AMIDES FOR THE PREVENTION AND/OR TREATMENT OF STEATOHEPATITIS
    Publication number: 20180193293
    Abstract: The invention relates to the use of fatty acid amides with phenylalkylamines and of a pharmaceutical composition comprising at least one of these compounds in the prevention and/or treatment of fatty liver or a pathological condition or disease caused by fatty liver, either alcoholic or non-alcoholic, and, in particular, for the prevention and/or treatment of the alcoholic steatohepatitis or non-alcoholic steatohepatitis (NASH).
    Type: Application
    Filed: November 24, 2015
    Publication date: July 12, 2018
    Inventors: Fernando RODRÍGUEZ DE FONSECA, Francisco Javier PAVÓN MORÓN, Juan Manuel DECARA DEL OLMO, Antonia SERRANO CRIADO, Jesús JOGLAR TAMARGO, Pedro CLAPÉS SABORIT, Rafael DE LA TORRE FORNELL, Magí FERRÉ ALBALADEJO, María Isabel COVAS PLANELLS, Montserrat FITO COLOMER, Bruno ALMEIDA COTRIM
  • HYDROXYTYROSOL ETHERS
    Publication number: 20130267588
    Abstract: The invention relates to hydroxytyrosol ethers derived from fatty alcohols and phenolic compounds of olive oil and the salts, solvates and hydrates thereof, which have an affinity for type 1 cannabinoid receptors (CB1) and which can: prevent the oxidation of low-density lipoprotein (LDL); and modulate the actions regulated by said receptor, such as inducing satiety, controlling intake and reducing body fat.
    Type: Application
    Filed: December 19, 2011
    Publication date: October 10, 2013
    Applicants: FUNDACIO IMIM, FUNDACION INSTITUTO MEDITERRANEO PARA EL AVANCE DE LA BIOTECNOLOGIA Y LA INVESTIGACION SANITARIA, CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
    Inventors: Rafael De La Torre Fornell, Magin Farre Albaladejo, Maria Isabel Covas Planells, Montserrat Fito Colomer, Bruno Almeida Cotrim, Fernando Rodriguez De Fonseca, Juan Manuel Decara Del Olmo, Miguel Romero Cuevas, Jesus Joglar Tamargo, Pedro Clapes Saborit