Patents by Inventor Pedro Rodriguez

Pedro Rodriguez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200249239
    Abstract: The present invention provides a method of quantifying the activity of a protein modifying enzyme in a sample, comprising calculating the value K for said protein-modifying enzyme on the basis of the number of modified peptides in a sample that are substrates of said protein modifying enzyme, the intensity of the modified peptides, each modified peptide in the sample that is a substrate of said protein modifying enzyme, the total number of modified peptides in the sample, the intensity of the modified peptides and all of the modified peptides in the sample. A method of quantifying the activity of a protein modifying enzyme in a sample, comprising calculating the value SC for said protein-modifying enzyme on the basis of a reduction in proliferation using an inhibitor at an inhibitor concentration at which proliferation is measured and the “in vitro” IC50i of the inhibitor against a primary target is also provided.
    Type: Application
    Filed: November 16, 2016
    Publication date: August 6, 2020
    Inventors: Pedro Rodriguez CUTILLAS, Edmund WILKES, Pedro CASADO-IZQUIERDO
  • Patent number: 10700578
    Abstract: Unique systems, methods, techniques and apparatuses of an exciterless synchronous generator are disclosed. One exemplary embodiment is an exciterless synchronous generator comprising a stator, a rotor, and a startup excitation system. The stator includes a set of stator windings. The rotor includes an energy harvest winding, a DC power supply including a DC bus and coupled to the energy harvest winding, and a field winding coupled to the DC power supply. The startup excitation system comprises one of a magnetic field generation system structured to generate a magnetic field received by the energy harvest winding in response to a rotation of the rotor, wherein the magnetic field is converted to DC power with the DC power supply and transmitted to the field winding; or a rotor DC power source including and diode coupled in series across the DC bus.
    Type: Grant
    Filed: December 29, 2017
    Date of Patent: June 30, 2020
    Assignee: ABB Schweiz AG
    Inventors: Ghanshyam Shrestha, Chenjie Lin, Mehanathan Pathmanathan, Pedro Rodriguez
  • Publication number: 20200110133
    Abstract: A rotor bar fault in a rotor of an electrical machine having a plurality of rotor bars and an end ring configured to short circuit the rotor bars. The method includes the steps of measuring a first temperature at a first end ring location, and measuring a second temperature at a second end ring location, the second end ring location being different from the first end ring location. As broken rotor bars cause a non-uniform temperature distribution in the end ring, the detection of rotor bar faults can be based on monitored temperatures at different end ring locations.
    Type: Application
    Filed: March 6, 2018
    Publication date: April 9, 2020
    Inventors: Pedro Rodriguez, Subrat Sahoo
  • Publication number: 20200076286
    Abstract: Unique systems, methods, techniques and apparatuses of exciterless synchronous machines are disclosed. One exemplary embodiment is a fractional slot synchronous machine comprising a rotor including a first pole pair including a first pole including a first plurality of slots having a first center point and arranged on a first outer surface in a slot pattern; a second pole pair including a second pole including a second plurality of slots having a second center point and arranged on a second outer surface in the slot pattern; energy harvest windings arranged in a winding pattern within a portion of the first plurality of slots and arranged in the same winding pattern within a portion of the second plurality of slots, the energy harvest winding being structured to receive a harmonic power from the stator; and a rectifier structured to receive the harmonic power from the energy harvest winding.
    Type: Application
    Filed: September 4, 2018
    Publication date: March 5, 2020
    Inventors: Chenjie Lin, Ghanshyam Shrestha, Mehanathan Pathmanathan, Pedro Rodriguez, Jan Mikael Westerlund, Tuomas Janhunen
  • Patent number: 10581357
    Abstract: Unique systems, methods, techniques and apparatuses of a rotating DC power supply are disclosed. One exemplary embodiment includes a first and second DC bus rail, a first and second leg, and a discharge resistor. The first leg includes a first semiconductor device and a second semiconductor device coupled in series at a first midpoint connection, the first semiconductor device being coupled to a first point on the first DC bus rail and the first midpoint connection being coupled to a field winding. The second leg includes a third semiconductor device and a fourth semiconductor device coupled in series at a second midpoint connection, the third semiconductor device being coupled to a second point on the first DC bus rail and the second midpoint connection being coupled to the field winding. The discharge resistor is operatively coupled to the first DC bus rail between the first point and the second point.
    Type: Grant
    Filed: May 11, 2018
    Date of Patent: March 3, 2020
    Assignee: ABB Schweiz AG
    Inventors: Chenjie Lin, Ghanshyam Shrestha, Mehanathan Pathmanathan, Pedro Rodriguez, Pasi Paloheimo, Tuomas Janhunen, Susanna Bäckström-Andersson, Eino Silander
  • Publication number: 20200057110
    Abstract: A method for detecting a fault in an AC/AC exciter having an exciter rotor and an exciter stator. A signal reflecting the current or voltage, is obtained at an exciter rotor winding or at an exciter stator winding. A frequency analysis is applied and on the basis of a presence of a frequency component, a rotor current or voltage signal, at a first frequency fs*(2?s), where fs is a supply frequency of the exciter stator and s is an exciter slip, it is determined whether the exciter suffers from an inter-turn short circuit in an exciter stator winding or not. On the basis of a presence of a frequency component, in the case of a stator current signal or a stator voltage signal, at a second frequency fs*(1?2*s), it is determined whether the exciter suffers from an inter-turn short circuit in an exciter rotor winding or not. Presence of frequency components at the first and/or second frequencies in windings of an AC/AC exciter indicate the mentioned fault conditions.
    Type: Application
    Filed: September 22, 2017
    Publication date: February 20, 2020
    Inventors: Pedro RODRIGUEZ, Matti KIVIOJA, Janne HOLLA, Tapio RAUHALA, Ilari KARKKAINEN
  • Publication number: 20190348936
    Abstract: Unique systems, methods, techniques and apparatuses of a rotating DC power supply are disclosed. One exemplary embodiment includes a first and second DC bus rail, a first and second leg, and a discharge resistor. The first leg includes a first semiconductor device and a second semiconductor device coupled in series at a first midpoint connection, the first semiconductor device being coupled to a first point on the first DC bus rail and the first midpoint connection being coupled to a field winding. The second leg includes a third semiconductor device and a fourth semiconductor device coupled in series at a second midpoint connection, the third semiconductor device being coupled to a second point on the first DC bus rail and the second midpoint connection being coupled to the field winding. The discharge resistor is operatively coupled to the first DC bus rail between the first point and the second point.
    Type: Application
    Filed: May 11, 2018
    Publication date: November 14, 2019
    Inventors: Chenjie Lin, Ghanshyam Shrestha, Mehanathan Pathmanathan, Pedro Rodriguez, Pasi Paloheimo, Tuomas Janhunen, Susanna Backstrom-Andersson, Eino Silander
  • Publication number: 20190207484
    Abstract: Unique systems, methods, techniques and apparatuses of an exciterless synchronous generator are disclosed. One exemplary embodiment is an exciterless synchronous generator comprising a stator, a rotor, and a startup excitation system. The stator includes a set of stator windings. The rotor includes an energy harvest winding, a DC power supply including a DC bus and coupled to the energy harvest winding, and a field winding coupled to the DC power supply. The startup excitation system comprises one of a magnetic field generation system structured to generate a magnetic field received by the energy harvest winding in response to a rotation of the rotor, wherein the magnetic field is converted to DC power with the DC power supply and transmitted to the field winding; or a rotor DC power source including and diode coupled in series across the DC bus.
    Type: Application
    Filed: December 29, 2017
    Publication date: July 4, 2019
    Inventors: Ghanshyam Shrestha, Chenjie Lin, Mehanathan Pathmanathan, Pedro Rodriguez
  • Publication number: 20190164090
    Abstract: An apparatus includes a process scanner and a processor connected with the process scanner. The processor is configured to retrieve, via the processing scanner, operation information indicative of a serial number of an operation, an operation number, an order number of an order associated with the operation, a work time spent on the operation, and a material number of a material associated with the operation. The processor associates the operation information with a first user assigned to the operation, and saves, to a history database, a process record. The record includes the first user, a time element, a location of the operation, a completion status of the operation, a current status of the operation, and one or more turnbacks of the operation. The processor outputs to a display a graphic of the operation information and a balance of user time associated with the operation information.
    Type: Application
    Filed: November 28, 2017
    Publication date: May 30, 2019
    Inventors: Alfredo Rodriguez Diaz, Pedro E. Rivera Figueroa, Wilfredo Xavier Perez-Jimenez, Orlando Rosado Nieves, Jose A. Gonzalez Velez, Ahmed David Costas Lopez, Migna Delgado Ocasio, Radames Tricoche Pedrogo, Luis R. Soto Guzman
  • Publication number: 20180321321
    Abstract: A method and device of determining a fault condition in a synchronous motor including a rotor provided with damper bars and an end ring to which the damper bars are mechanically connected thereby forming a damper cage, wherein the method includes: obtaining a first measurement of an end ring current from a first location along the end ring, processing the first measurement to thereby obtain a processing result, and determining whether a fault condition is present in the synchronous motor based on the processing result.
    Type: Application
    Filed: April 26, 2018
    Publication date: November 8, 2018
    Inventors: Pedro RODRIGUEZ, Subrat SAHOO, Cajetan PINTO
  • Patent number: 10088506
    Abstract: A method for identifying a fault condition in an electrical machine in which at least a stator or a rotor has parallel winding branches is disclosed. A measurement is carried out for obtaining a set of circulating current values between two parallel winding branches of which each winding branch includes a single coil. A frequency analysis is applied on the set of circulating current values to obtain at least one frequency component. A fault condition of the electrical machine is determined on the basis of the at least one frequency component.
    Type: Grant
    Filed: October 3, 2013
    Date of Patent: October 2, 2018
    Assignee: ABB Research Ltd.
    Inventors: Pedro Rodriguez, Cajetan Pinto, Maciej Orman, Michal Orkisz, Ulf Ahrend, Rolf Disselnkötter, Pawel Rzeszucinski, James Ottewill
  • Publication number: 20180269753
    Abstract: A method for preventing a frequency component of a voltage from occurring in an electrical machine including the steps of: obtaining, either by measuring a voltage signal or a current signal from the electrical machine in time domain and transforming the measured signal into frequency domain, by simulating or deducing a first frequency component present in the electrical machine in absence of a grounding, the first frequency component representing a first undesired frequency higher than a limit frequency of 500 Hz; and providing the electrical machine with a first grounding at a grounding location, the first grounding including a resonant circuit resonating at the first undesired frequency. In order to get rid of harmful shaft voltages in the form of sharp voltage peaks at high frequencies, it is first necessary to determine at which undesired frequency or frequencies these voltage peaks occur.
    Type: Application
    Filed: October 4, 2016
    Publication date: September 20, 2018
    Inventors: Pedro RODRIGUEZ, Subrat SAHOO, Cajetan PINTO, Klaus VÄNSKÄ
  • Publication number: 20180217129
    Abstract: The present invention provides methods of assessing protein modification status and identifying biomarkers linked to cell signaling pathways. The invention provides a method of creating a dataset of modification sites, comprising grouping modification sites on modified peptides from a first sample which has been treated with a first modulator of a protein modifying enzyme and modification sites on modified peptides from a second sample which has been treated with a second modulator of the same protein modifying enzyme into a single group, according to the effect of said first and second modulators of said protein modifying enzyme on said modification sites, wherein said first and second modulators of said protein modifying enzyme are different. The invention further provides a method of preparing a database, methods of treatment and methods of diagnosis.
    Type: Application
    Filed: June 3, 2016
    Publication date: August 2, 2018
    Applicant: Queen Mary University of London
    Inventors: Pedro Rodriguez Cutillas, Edmund Wilkes
  • Patent number: 9977085
    Abstract: A method and system of determining an electro-mechanical fault condition in a synchronous machine having a stator, a rotor, and exciter. The method includes: a) obtaining an exciter current signal which is a measurement of an exciter current through stationary windings of the exciter, b) transforming the exciter current signal to obtain an exciter current frequency spectrum, and c) determining whether an electro-mechanical fault condition is present, and a type of the electro-mechanical fault condition, based on harmonic content related to the frequency of the stator, of the exciter current frequency spectrum.
    Type: Grant
    Filed: September 8, 2015
    Date of Patent: May 22, 2018
    Assignee: ABB Schweiz AG
    Inventors: Pedro Rodriguez, Subrat Sahoo, Cajetan Pinto
  • Patent number: 9945907
    Abstract: A method of determining a fault condition in a synchronous machine. The method includes a) obtaining a field current signal and a shaft voltage signal of the synchronous machine, b) transforming the field current signal and the shaft voltage signal to obtain a field current frequency spectrum and a shaft voltage frequency spectrum, and c) determining whether a fault condition is present, and in case a fault condition is present identifying a type of the fault condition, based on harmonic content of the field current frequency spectrum and harmonic content of the shaft voltage frequency spectrum, wherein c) includes comparing the harmonic content of the field current frequency spectrum with fault condition field current signature spectra and comparing the harmonic content of the shaft voltage frequency spectrum with fault condition shaft voltage signature spectra.
    Type: Grant
    Filed: March 4, 2015
    Date of Patent: April 17, 2018
    Assignee: ABB Schweiz AG
    Inventors: Pedro Rodriguez, Subrat Sahoo
  • Publication number: 20180052206
    Abstract: A method and system of determining an electro-mechanical fault condition in a synchronous machine having a stator, a rotor, and exciter. The method includes: a) obtaining an exciter current signal which is a measurement of an exciter current through stationary windings of the exciter, b) transforming the exciter current signal to obtain an exciter current frequency spectrum, and c) determining whether an electro-mechanical fault condition is present, and a type of the electro-mechanical fault condition, based on harmonic content related to the frequency of the stator, of the exciter current frequency spectrum.
    Type: Application
    Filed: September 8, 2015
    Publication date: February 22, 2018
    Inventors: Pedro RODRIGUEZ, Subrat SAHOO, Cajetan PINTO
  • Patent number: 9879304
    Abstract: The present invention provides a method of quantifying the activity of a protein modifying enzyme in a sample, comprising: (i) grouping modified peptides from a first sample and modified peptides from a second sample into a single group according to one of the following parameters: (a) modified peptides having a modification site that is modified by the same protein modifying enzyme; or (b) modified peptides having a modification site that is part of the same modification motif; (ii) calculating enrichment of the modified peptides from the first sample compared to the modified peptides from the second sample in the group; and (iii) calculating the statistical significance of said enrichment; wherein a statistically significant enrichment is indicative of a protein modifying enzyme being activated in the first sample compared to the second sample. In some embodiments, the method further comprises identifying modified peptides in a first sample and a second sample using mass spectrometry (MS) prior to step (i).
    Type: Grant
    Filed: March 8, 2013
    Date of Patent: January 30, 2018
    Assignee: Queen Mary & Westfield College, University of London
    Inventor: Pedro Rodriguez Cutillas
  • Patent number: 9823308
    Abstract: A method for discovering demagnetisation faults of a permanent magnet synchronous generator, such as a wind power generator. The method is performed during operation of the synchronous generator and includes measuring the vibration of the stator, performing a frequency analysis of the vibration, and deducing whether the generator suffers from demagnetization of a permanent magnet, from the vibration analysis. Moreover, geometric eccentricity faults and electric short circuit faults may also be detected from the vibration.
    Type: Grant
    Filed: October 29, 2013
    Date of Patent: November 21, 2017
    Assignee: ABB Schweiz AG
    Inventor: Pedro Rodriguez
  • Patent number: 9747412
    Abstract: The present invention provides a method for identifying differential activation of a bisubstrate protein modifying enzyme between samples, comprising: (i) incubating a first sample with x different concentrations of the non-protein substrate of said enzyme, wherein x is 2 or greater than 2; (ii) quantifying modification of a polypeptide in said sample at each of the x different concentrations of the non-protein substrate; (iii) determining the affinity of said enzyme for said non-protein substrate; (iv) repeating steps (i) to (iii) for a second or subsequent sample; and (v) comparing the affinity of said enzyme for said non-protein substrate between said samples; wherein a difference in affinity of said enzyme for said non-protein substrate between samples is indicative of differential activation of said enzyme between samples. The present invention also provides a method for identifying an in vivo substrate of a bisubstrate protein modifying enzyme.
    Type: Grant
    Filed: October 18, 2011
    Date of Patent: August 29, 2017
    Assignee: HVIVO SERVICES LIMITED
    Inventors: Pedro Rodriguez Cutillas, Bart Vanhaesebroeck, Luisa Marie Beltran
  • Publication number: 20170016960
    Abstract: A method of determining a fault condition in a synchronous machine. The method includes a) obtaining a field current signal and a shaft voltage signal of the synchronous machine, b) transforming the field current signal and the shaft voltage signal to obtain a field current frequency spectrum and a shaft voltage frequency spectrum, and c) determining whether a fault condition is present, and in case a fault condition is present identifying a type of the fault condition, based on harmonic content of the field current frequency spectrum and harmonic content of the shaft voltage frequency spectrum, wherein c) includes comparing the harmonic content of the field current frequency spectrum with fault condition field current signature spectra and comparing the harmonic content of the shaft voltage frequency spectrum with fault condition shaft voltage signature spectra.
    Type: Application
    Filed: March 4, 2015
    Publication date: January 19, 2017
    Inventors: Pedro Rodriguez, Subrat Sahoo