Patents by Inventor Pedro Saura

Pedro Saura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20070160575
    Abstract: A recombinant chimeric antagonist formed by a 60 amino acid fragment of the N-terminal region of human interleukin 2 (IL-2) fused to the N-terminal of the extracellular region of the alpha subunit of the gamma IFN (IFN ?) receptor. In vitro this protein has a T cell growth stimulating activity, it inhibits the growth stimulating activity of IL-2 in T cells, it inhibits the induction of HLA-DR by IFN ? and it inhibits the antiproliferative activity of ? IFN. This invention can be applied in the field of medicine for the treatment of several pathologies such as autoimmune diseases, graft rejections, chronic inflammations, sepsis, ischemia and reperfusion syndrome and atherosclerosis.
    Type: Application
    Filed: January 22, 2007
    Publication date: July 12, 2007
    Inventors: Iraldo Rivero, Yeny Ruiz, Elizabeth Garces, Giselle Roll, Pedro Saura
  • Publication number: 20060073115
    Abstract: A recombinant chimeric antagonist formed by a 60 amino acid fragment of the N-terminal region of human interleukin 2 (IL-2) fused to the N-terminal of the extracellular region of the alpha subunit of the gamma IFN (IFN ?) receptor. In vitro this protein has a T cell growth stimulating activity, it inhibits the growth stimulating activity of IL-2 in T cells, it inhibits the induction of HLA-DR by IFN ? and it inhibits the antiproliferative activity of ? IFN. This invention can be applied in the field of medicine for the treatment of several pathologies such as autoimmune diseases, graft rejections, chronic inflammations, sepsis, ischemia and reperfusion syndrome and atherosclerosis.
    Type: Application
    Filed: May 8, 2003
    Publication date: April 6, 2006
    Inventors: Iraldo Rivero, Yeny Ruiz, Elizabeth Garces, Giselle Roll, Pedro Saura