Patents by Inventor Peech S. Reedy

Peech S. Reedy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Unsymmetrically linked bisnaphthalimides as antitumor agents
    Patent number: 5604095
    Abstract: The present invention provides novel bis-naphthalimides characterized by having a linker containing a heteroatom, their preparation, pharmaceutical compositions thereof, and various methods of using the bis-naphthalimides. Particularly preferred bis-naphthalimides have a linker of about 8-16 atoms where the heteroatom is oxygen, sulfur, sulfur oxide or sulfur dioxide. The bis-naphthalimides provided herein have exceptional DNA binding properties and demonstrate cytotoxicity in both in vitro and in vivo tumor models, in particular, against melanoma.
    Type: Grant
    Filed: July 22, 1994
    Date of Patent: February 18, 1997
    Assignee: Cancer Therapy & Research Center
    Inventors: Alexander L. Weis, Shih-Fong Chen, Peech S. Reedy, Mallaiah Mittakanti, Daniel L. Dexter