Abstract: This disclosure relates to systems and methods that identify, predict, and rank immunogenic T-cell epitopes. In particular, this disclosure identifies epitopes that arose from disease-associated mutations, wherein the epitopes are predicted to elicit immune response from T cells. Specifically, this disclosure simultaneously considers peptide-level information, including MHC Class I and II presentation, helper and cytotoxic T cell response and sample-level information, including mutation clonality and MHC allele dosage. In some embodiment, the systems and methods are used for personalized treatment of cancers.

Abstract: A touch panel and a touch display panel are provided. The touch panel comprises: a touch layer provided with a plurality of first microstructures on an upper surface of the touch layer; and a cover plate provided with a plurality of second microstructures on a lower surface of the cover plate, wherein the second microstructures are adapted to the first microstructures, the cover plate is provided on the upper surface of the touch layer, and the plurality of second microstructures are adsorbed and self-locking connected to the plurality of first microstructures.

Abstract: A touch panel and a touch display panel are provided. The touch panel comprises: a touch layer provided with a plurality of first microstructures on an upper surface of the touch layer; and a cover plate provided with a plurality of second microstructures on a lower surface of the cover plate, wherein the second microstructures are adapted to the first microstructures, the cover plate is provided on the upper surface of the touch layer, and the plurality of second microstructures are adsorbed and self-locking connected to the plurality of first microstructures.

Abstract: This disclosure relates to systems and methods that identify, predict, and rank immunogenic T-cell epitopes. In particular, this disclosure identifies epitopes that arose from disease-associated mutations, wherein the epitopes are predicted to elicit immune response from T cells. Specifically, this disclosure simultaneously considers peptide-level information, including MHC Class I and II presentation, helper and cytotoxic T cell response and sample-level information, including mutation clonality and MHC allele dosage. In some embodiment, the systems and methods are used for personalized treatment of cancers.

Abstract: The present disclosure discloses a color film substrate and a method for manufacturing the same as well as a liquid crystal display panel. The color film substrate includes: a substrate, a black matrix disposed on the substrate, and an antireflection layer disposed between the substrate and the black matrix. The refractive index of the antireflection layer is about 1.6˜2.0, and the thickness of the antireflection layer is greater than 100 nm; or the refractive index of the antireflection layer is about 1.5˜2.4, and the thickness of the antireflection layer is less than 60 nm. In the aforesaid way, the present disclosure can decrease the reflectance of the liquid crystal display panel in a simpler manner and at a lower cost, thereby improving the display quality of the liquid crystal display panel under the environment of strong light.

Abstract: The present invention provides a backlight module and a display apparatus. The backlight module comprises a substrate, a plurality of light sources disposed on the substrate; and a light guide sheet disposed on the substrate, wherein the light guide sheet includes a plurality of curved recesses, and the light sources are received in the curved recesses. The present invention can decrease an amount of the light sources.

Abstract: The present invention provides a backlight module and a display apparatus. The backlight module comprises a substrate, a plurality of light sources disposed on the substrate; and a light guild sheet disposed on the substrate, wherein the light guild sheet includes a plurality of curved recesses, and the light sources are received in the curved recesses. The present invention can decrease an amount of the light sources.

Abstract: The present invention discloses a thin-film transistor array substrate and a manufacturing method thereof. The method includes steps of using a first multi-tone adjustment mask to form a gate electrode and a common electrode after depositing a first transparent conductive layer and a first metallic layer on a substrate; depositing a gate-insulating layer and a semiconductor layer and then using a first mask to retain a part of the semiconductor layer that is on a top of the gate electrode; depositing a second transparent conductive layer and a second metallic layer, and using a second multi-tone adjustment mask to form a source electrode, a drain electrode and a pixel electrode.

Abstract: The present invention provides a thin film transistor (TFT) array substrate and a method for manufacturing the same. A transparent and electrically conductive layer and a first metal layer are deposited on a substrate, and a first multi tone mask is utilized to form gate electrodes and common electrodes. A gate insulating layer, a semiconductor layer and a second metal layer are deposited on the substrate, and a second multi tone mask is utilized to form source electrodes, drain electrodes and pixel electrodes. The present invention can simplify the manufacturing process thereof.

Abstract: The present invention discloses an engaged type liquid crystal module. By engaging a first groove disposed in the middle of an outer surface of a backlight module with a first flange of a front frame structure, it can assemble a liquid crystal module, and can save a volume occupied by screw members. The engaged type liquid crystal module according to the present invention can simplify the frame design of the liquid crystal module, and match with a corresponding outer housing of display device to process an assembly operation without screw members, so that it is further advantageous for a development trend that liquid crystal display is designed toward narrow frame.

Abstract: The present invention relates to a display device, which comprises a rear cover, a display panel, a drive device and an adhesive member, the adhesive member including a first surface and a second surface opposite to the first surface; the first surface is bonded to the upper end of the rear cover, and the second surface is bonded to the upper end of the display panel, which is bonded at the lower end to the lower end of the rear cover; the drive device is arranged in the rear cover and electrically connected to the display panel to drive the display panel.

Abstract: The present invention provides a liquid crystal display (LCD) panel and a display apparatus using the same. The LCD panel comprises a first substrate, a second substrate and a liquid crystal layer. The second substrate comprises pixels, wherein, when images are displayed by the pixels, a voltage difference between a first voltage of the first sub-pixels and a second voltage of the second sub-pixels is inversely proportional to a grayscale of the images displayed by the pixels, and the first voltage is higher than the second voltage. The present invention can mitigate the viewing angle problem of the pixels.

Abstract: The present invention discloses a liquid crystal module having F-type frames and an assembly method thereof. An F-type frame assembly according to the present invention is assembled by a plurality of F-type frames. Each of the F-type frames has a cross-section of F shape, and has a first opening portion located in an upper half thereof and a second opening portion located in a lower half thereof. Besides, the first opening portions and the second opening portions of all of the F-type frames are correspondingly facing inward, so as to form a first receiving space and a second receiving space, respectively. In the present invention, by placing a liquid crystal panel in the first receiving space and placing a backlight module in the second receiving space, a liquid crystal module is assembled.

Abstract: The present invention provides a backlight module and a display apparatus. The backlight module comprises a substrate, a plurality of light sources disposed on the substrate; and a light guild sheet disposed on the substrate. The light guild sheet includes first recesses and second recesses, and the light sources are received in the first recesses, and the second recesses are formed a light output surface thereof. The present invention can form a uniform plane light source.

Abstract: The present invention provides a liquid crystal display (LCD) panel and a display apparatus using the same. The LCD panel comprises a first substrate, a second substrate, a liquid crystal layer and quarter wave (?/4) pattern retarder films. The second electrode of the second substrate comprises first sub-pixels and second sub-pixels. When images are displayed by the pixels, a voltage difference between a first voltage of the first sub-pixels and a second voltage of the second sub-pixels is inversely proportional to a grayscale of the images displayed by the pixels. The present invention can mitigate the viewing angle problem of the pixels.

Abstract: The present invention discloses a thin-film transistor array substrate and a manufacturing method thereof. The method includes steps of using a first multi-tone adjustment mask to form a gate electrode and a common electrode after depositing a first transparent conductive layer and a first metallic layer on a substrate; depositing a gate-insulating layer and a semiconductor layer and then using a first mask to retain a part of the semiconductor layer that is on a top of the gate electrode; depositing a second transparent conductive layer and a second metallic layer, and using a second multi-tone adjustment mask to form a source electrode, a drain electrode and a pixel electrode.

Abstract: The present invention discloses an array substrate, which includes a thin-film transistor, a data line, a gate line, and a pixel electrode. The array substrate further includes a common electrode. The common electrode has a first region, a second region, and at least one opening. The first region is defined on the common electrode, and the first region is a projection of the pixel electrode on a plane where the common electrode is located. The second region is defined on the common electrode, and the second region is close to at least one edge of the first region. The at least one opening is disposed on the second region of the common electrode.

Abstract: A display device comprises a rear cover, a display panel, a drive device, an upper end guide frame, a lower end guide frame, a first adhesive member, and a second adhesive member, the rear cover including a bottom wall, an upper end sidewall and a lower end sidewall; the rear cover further includes an upper end coupling portion, an upper end support portion, a lower end coupling portion and a lower end support portion; the upper end guide frame includes an upper end panel support portion and an upper end guide sidewall, the first adhesive member bonding the upper end panel support portion to the upper end of the display panel; the lower end guide frame includes a lower end guide sidewall and a lower end panel support portion, the second adhesive member bonding the lower end panel support portion to the lower end of the display panel.

Abstract: The present invention provides a liquid crystal display (LCD) panel and a display apparatus using the same. The LCD panel comprises a first substrate, a second substrate and a liquid crystal layer. The second substrate comprises pixels, wherein, when images are displayed by the pixels, a voltage difference between a first voltage of the first sub-pixels and a second voltage of the second sub-pixels is inversely proportional to a grayscale of the images displayed by the pixels, and the first voltage is higher than the second voltage. The present invention can mitigate the viewing angle problem of the pixels.

Abstract: The present invention discloses an engaged type liquid crystal module. By engaging a first groove disposed in the middle of an outer surface of a backlight module with a first flange of a front frame structure, it can assemble a liquid crystal module, and can save a volume occupied by screw members. The engaged type liquid crystal module according to the present invention can simplify the frame design of the liquid crystal module, and match with a corresponding outer housing of display device to process an assembly operation without screw members, so that it is further advantageous for a development trend that liquid crystal display is designed toward narrow frame.