Abstract: The invention relates to Cu-embedded masterbatches forming by a novel formulation and its production process. The novel formulation comprises a mixing powder prepared from Cu2O and ZnO. The mixing powder is milled in water to form slurry. Spray-dry the slurry at 130˜150° C. to get anti-bacterial powder. Add 12 wt. %˜15 wt. % of the anti-bacterial powder to plastic masterbatches and follow by pre-mixing, heating, stirring, melting, extruding, cooling and cutting process to obtain the Cu-embedded masterbatches.