Abstract: A method and apparatus for constructing a drug knowledge graph are provided. The method may include: identifying entities in a drug text; replacing medical key entities among the entities with character strings that conform to a preset rule, to obtain a replaced text; restoring the character strings in a word segmentation result, determined based on the replaced text, to the medical key entities replaced by the character strings; forming a linear entity relationship between the entities based on the entities; and generating a drug knowledge graph according to a parsing result obtained by syntactically parsing the linear entity relationship.

Abstract: The disclosure belongs to the technical field of liquid crystal materials, and specifically relates to a polymerizable compound, a preparation method therefor, and the use thereof. The polymerizable compound has a structure as shown in general formula I. Compared with the existing polymerizable RM, the polymerizable compound has the advantages of a good solubility, a faster polymerization rate, a more complete extent of polymerization, and less residues, thereby improving the problem of poor display to a great extent.

Abstract: A method and apparatus for constructing a drug knowledge graph are provided. The method may include: identifying entities in a drug text; replacing medical key entities among the entities with character strings that conform to a preset rule, to obtain a replaced text; restoring the character strings in a word segmentation result, determined based on the replaced text, to the medical key entities replaced by the character strings; forming a linear entity relationship between the entities based on the entities; and generating a drug knowledge graph according to a parsing result obtained by syntactically parsing the linear entity relationship.

Abstract: The disclosure belongs to the technical field of liquid crystal materials, and specifically relates to a polymerizable compound, a preparation method therefor, and the use thereof. The polymerizable compound has a structure as shown in general formula I. Compared with the existing polymerizable RM, the polymerizable compound has the advantages of a good solubility, a faster polymerization rate, a more complete extent of polymerization, and less residues, thereby improving the problem of poor display to a great extent.

Abstract: The disclosure discloses a genetically engineered strain for sarcosine production as well as a construction method and application. The genetically engineered strain is obtained by using Escherichia coli as a host and by integrating a single copy of imine reductase gene dpkA on its genome; singly copying citrate synthase gene gltA; knocking out glyoxylate cycle inhibitor gene iclR; knocking out malate synthase gene aceB; integrating a single copy of isocitrate lyase gene aceA; integrating a single copy of membrane-bound transhydrogenase gene pntAB; knocking out 2-ketate reductase gene ycdW; integrating a single copy of phosphoenolpyruvate carboxylase gene ppc; and knocking out pyruvate kinase gene pykF. After system metabolism transformation, the engineered strain can synthesize sarcosine with glucose and methylamine as main raw materials. The sarcosine titer can reach 10 g/L after fermentation for 30 h in a 5 L fermenter.

Abstract: The disclosure discloses a genetically engineered strain for sarcosine production as well as a construction method and application. The genetically engineered strain is obtained by using Escherichia coli as a host and by integrating a single copy of imine reductase gene dpkA on its genome; singly copying citrate synthase gene gltA; knocking out glyoxylate cycle inhibitor gene iclR; knocking out malate synthase gene aceB; integrating a single copy of isocitrate lyase gene aceA; integrating a single copy of membrane-bound transhydrogenase gene pntAB; knocking out 2-ketate reductase gene ycdW; integrating a single copy of phosphoenolpyruvate carboxylase gene ppc; and knocking out pyruvate kinase gene pykF. After system metabolism transformation, the engineered strain can synthesize sarcosine with glucose and methylamine as main raw materials. The sarcosine titer can reach 10 g/L after fermentation for 30 h in a 5 L fermenter.

Abstract: The present invention discloses a hand-held autonomous visual acuity measurement apparatus and a visual acuity measuring method. The invention comprises a corneal curvature measurement module comprising a first light source for emitting a first light beam and a first image collector for collecting an image formed from the first light beam after it has been reflected by cornea, the first image collector being movably provided in the corneal curvature measurement optical path of the corneal curvature measurement module, and the corneal curvature measurement module further comprises a first motor for driving the first image collector to move along the corneal curvature measurement optical path so that the first image collector moves to the imaging position.

Abstract: Disclosed is an optometry apparatus capable of measuring para-central defocus, comprising a diopter measurement module. The diopter measurement module comprises a first light source (1) emitting a first light beam. The optometry apparatus also comprises a scanning module for adjusting the position of a light spot formed on the retina by the first light beam. The scanning module comprises a first reflecting mirror (3) and a second reflecting mirror (5) rotatably positioned in sequence in the emergent optical path of the first light source (1). The rotation axis of the first reflecting mirror (3) and the rotation axis of the second reflecting mirror (5) form therebetween an angle greater than 0 degree and less than 180 degrees.

Abstract: The present invention discloses a hand-held autonomous visual acuity measurement apparatus and a visual acuity measuring method. The invention comprises a corneal curvature measurement module comprising a first light source for emitting a first light beam and a first image collector for collecting an image formed from the first light beam after it has been reflected by cornea, the first image collector being movably provided in the corneal curvature measurement optical path of the corneal curvature measurement module, and the corneal curvature measurement module further comprises a first motor for driving the first image collector to move along the corneal curvature measurement optical path so that the first image collector moves to the imaging position.

Abstract: Disclosed is an optometry apparatus capable of measuring para-central defocus, comprising a diopter measurement module. The diopter measurement module comprises a first light source (1) emitting a first light beam. The optometry apparatus also comprises a scanning module for adjusting the position of a light spot formed on the retina by the first light beam. The scanning module comprises a first reflecting mirror (3) and a second reflecting mirror (5) rotatably positioned in sequence in the emergent optical path of the first light source (1). The rotation axis of the first reflecting mirror (3) and the rotation axis of the second reflecting mirror (5) form therebetween an angle greater than 0 degree and less than 180 degrees.