Abstract: An article of footwear includes a heel cup that is attached to the upper and extends from the sole structure to at least a portion of the rear heel collar of the upper. The heel cup may be uniformly molded with an upper portion, midportion, and lower portion and the upper portion has a smaller mediolateral length than the midportion, and the midportion and lower portion form a concave structure that receives the heel. The upper portion has a first configuration and is capable of distorting into a second configuration under a load of a user's foot when the user is donning the footwear. In the second configuration, at least part of the upper portion is lowered and is capable of returning to the first configuration after the load of the user's foot is removed. The midportion includes a peripheral portion that may be thicker than a central portion.

Abstract: An article of footwear includes a heel counter support situated on the upper and above the sole structure. The heel counter support may have at least two hollow receptacles with backward angles, a compressible component having two ends, and each one of the two hollow receptacles receives one end of the compressible component. The compressible component may have a first configuration and may be capable of distorting into a second configuration under a load of a user's foot when the user is donning the footwear. The compressible component may be capable of automatically returning to the first configuration after the user's foot in fully inserted into the footwear.

Abstract: An article of footwear includes an upper and a U-shaped foamed ankle collar. The ankle collar may form the topmost region of the foot receiving shoe opening and the foamed ankle collar may extend at least partially around and over a foot receiving shoe opening. The ankle collar is capable of being compressed by the user's heel during foot insertion and the ankle collar may exert pressure on the user's ankle once the foot is inserted. The ankle collar may have a flattened region along its length forming a downward angle from the topmost region toward the front of the article of footwear. The ankle collar may be located along at least a portion of an inner surface of a heel cup and the heel cup may have a shoe-horn like configuration. The ankle collar may reduce the dimensions of the shoe opening when not compressed.

Abstract: The disclosure belongs to the technical field of liquid crystal materials, and specifically relates to a polymerizable compound, a preparation method therefor, and the use thereof. The polymerizable compound has a structure as shown in general formula I. Compared with the existing polymerizable RM, the polymerizable compound has the advantages of a good solubility, a faster polymerization rate, a more complete extent of polymerization, and less residues, thereby improving the problem of poor display to a great extent.

Abstract: The disclosure discloses a genetically engineered strain for sarcosine production as well as a construction method and application. The genetically engineered strain is obtained by using Escherichia coli as a host and by integrating a single copy of imine reductase gene dpkA on its genome; singly copying citrate synthase gene gltA; knocking out glyoxylate cycle inhibitor gene iclR; knocking out malate synthase gene aceB; integrating a single copy of isocitrate lyase gene aceA; integrating a single copy of membrane-bound transhydrogenase gene pntAB; knocking out 2-ketate reductase gene ycdW; integrating a single copy of phosphoenolpyruvate carboxylase gene ppc; and knocking out pyruvate kinase gene pykF. After system metabolism transformation, the engineered strain can synthesize sarcosine with glucose and methylamine as main raw materials. The sarcosine titer can reach 10 g/L after fermentation for 30 h in a 5 L fermenter.

Abstract: The disclosure discloses a genetically engineered strain for sarcosine production as well as a construction method and application. The genetically engineered strain is obtained by using Escherichia coli as a host and by integrating a single copy of imine reductase gene dpkA on its genome; singly copying citrate synthase gene gltA; knocking out glyoxylate cycle inhibitor gene iclR; knocking out malate synthase gene aceB; integrating a single copy of isocitrate lyase gene aceA; integrating a single copy of membrane-bound transhydrogenase gene pntAB; knocking out 2-ketate reductase gene ycdW; integrating a single copy of phosphoenolpyruvate carboxylase gene ppc; and knocking out pyruvate kinase gene pykF. After system metabolism transformation, the engineered strain can synthesize sarcosine with glucose and methylamine as main raw materials. The sarcosine titer can reach 10 g/L after fermentation for 30 h in a 5 L fermenter.

Abstract: The present invention discloses a hand-held autonomous visual acuity measurement apparatus and a visual acuity measuring method. The invention comprises a corneal curvature measurement module comprising a first light source for emitting a first light beam and a first image collector for collecting an image formed from the first light beam after it has been reflected by cornea, the first image collector being movably provided in the corneal curvature measurement optical path of the corneal curvature measurement module, and the corneal curvature measurement module further comprises a first motor for driving the first image collector to move along the corneal curvature measurement optical path so that the first image collector moves to the imaging position.

Abstract: Disclosed is an optometry apparatus capable of measuring para-central defocus, comprising a diopter measurement module. The diopter measurement module comprises a first light source (1) emitting a first light beam. The optometry apparatus also comprises a scanning module for adjusting the position of a light spot formed on the retina by the first light beam. The scanning module comprises a first reflecting mirror (3) and a second reflecting mirror (5) rotatably positioned in sequence in the emergent optical path of the first light source (1). The rotation axis of the first reflecting mirror (3) and the rotation axis of the second reflecting mirror (5) form therebetween an angle greater than 0 degree and less than 180 degrees.

Abstract: The present invention discloses a hand-held autonomous visual acuity measurement apparatus and a visual acuity measuring method. The invention comprises a corneal curvature measurement module comprising a first light source for emitting a first light beam and a first image collector for collecting an image formed from the first light beam after it has been reflected by cornea, the first image collector being movably provided in the corneal curvature measurement optical path of the corneal curvature measurement module, and the corneal curvature measurement module further comprises a first motor for driving the first image collector to move along the corneal curvature measurement optical path so that the first image collector moves to the imaging position.

Abstract: Disclosed is an optometry apparatus capable of measuring para-central defocus, comprising a diopter measurement module. The diopter measurement module comprises a first light source (1) emitting a first light beam. The optometry apparatus also comprises a scanning module for adjusting the position of a light spot formed on the retina by the first light beam. The scanning module comprises a first reflecting mirror (3) and a second reflecting mirror (5) rotatably positioned in sequence in the emergent optical path of the first light source (1). The rotation axis of the first reflecting mirror (3) and the rotation axis of the second reflecting mirror (5) form therebetween an angle greater than 0 degree and less than 180 degrees.