Abstract: A hot spot defect detecting method and a hot spot defect detecting system are provided. In the method, hot spots are extracted from a design of a semiconductor product to define a hot spot map comprising hot spot groups, wherein local patterns in a same context of the design yielding a same image content are defined as a same hot spot group. During runtime, defect images obtained by an inspection tool performing hot scans on a wafer manufactured with the design are acquired and the hot spot map is aligned to each defect image to locate the hot spot groups. The hot spot defects in each defect image are detected by dynamically mapping the hot spot groups located in each defect image to a plurality of threshold regions and respectively performing automatic thresholding on pixel values of the hot spots of each hot spot group in the corresponding threshold region.

Abstract: Microelectromechanical devices and methods of manufacture are presented. Embodiments include bonding a mask substrate to a first microelectromechanical system (MEMS) device. After the bonding has been performed, the mask substrate is patterned. A first conductive pillar is formed within the mask substrate, and a second conductive pillar is formed within the mask substrate, the second conductive pillar having a different height from the first conductive pillar. The mask substrate is then removed.

Abstract: A semiconductor chip and a manufacturing method thereof are provided. The semiconductor chip includes: an array of pillar structures, disposed on a front surface of the semiconductor chip, and respectively including a ground pillar and multiple working pillars laterally spaced apart from and substantially parallel with a line portion of the ground pillar; and dummy pillar structures, disposed on the front surface of the semiconductor chip and laterally surrounding the pillar structures. Active devices formed inside the semiconductor chip are electrically connected to the working pillar. The ground pillars of the pillar structures and the dummy pillar structures are electrically connected to form a current pathway on the front surface of the semiconductor chip.

Abstract: A portable electronic device includes a base, a first display pivotally connected to the base, a second display, and a linkage mechanism. The first display is movable to be opened or closed relative to the base. The second display is located between the base and the first display. The linkage mechanism includes at least one first link. Two ends of the first link are pivotally connected to the first display and the second display, respectively. When the first display is opened relative to the base, the at least one first link rotates to drive the second display to move up relative to the base. When the first display is closed relative to the base, the at least one first link rotates in an opposite direction to drive the second display to move down to be accommodated between the first display and the base.

Abstract: The invention relates to antibody fusion proteins. Particularly, the invention relates to antibody fusion proteins for intra-cellular and intra-nucleus drugs delivery. The fusion protein of the invention can be used as a peptide penetration system that specifically binds to various targets for the delivery of effector peptides across a biological barrier.

Abstract: The present disclosure discloses a portable electronic device including a primary display panel, a keyboard module, a secondary display panel, and a support plate. The primary display panel includes a first pivot and a second pivot. The first pivot and the second pivot are disposed at the primary display panel. The keyboard module faces the primary display panel and includes a third pivot. One side of the secondary display panel is connected to the first pivot, and another side is a free side. The secondary display panel is flipped through the first pivot to be overlapped on an upper surface of the keyboard module or to abut against the upper surface at the free side. The support plate is flipped through the second pivot and the third pivot to be overlapped on the bottom surface of the primary display panel or to support the primary display panel.

Abstract: The present disclosure discloses a portable electronic device including a primary display panel, a keyboard module, a secondary display panel, and a support plate. The primary display panel includes a first pivot and a second pivot. The first pivot and the second pivot are disposed at the primary display panel. The keyboard module faces the primary display panel and includes a third pivot. One side of the secondary display panel is connected to the first pivot, and another side is a free side. The secondary display panel is flipped through the first pivot to be overlapped on an upper surface of the keyboard module or to abut against the upper surface at the free side. The support plate is flipped through the second pivot and the third pivot to be overlapped on the bottom surface of the primary display panel or to support the primary display panel.

Abstract: A portable electronic device includes a base, a first display, a second display, and a linkage mechanism. The first display is pivotally connected to the base, and the first display is movable to be opened or closed relative to the base. The second display is located between the base and the first display. The linkage mechanism includes at least one first link. Two ends of the first link are pivotally connected to the first display and the second display, respectively. When the first display is opened relative to the base, the at least one first link rotates to drive the second display to move up relative to the base. When the first display is closed relative to the base, the at least one first link rotates in an opposite direction to drive the second display to move down to be accommodated between the first display and the base.

Abstract: A beam shaping assembly for neutron capture therapy includes a beam inlet, a target having nuclear reaction with an incident proton beam from the beam inlet to produce neutrons forming a neutron beam, a moderator adjoining to the target, a reflector surrounding the moderator, a thermal neutron absorber adjoining to the moderator, a radiation shield arranged inside the beam shaping assembly and a beam outlet. The material of the moderator is subjected to a powder sintering process using a powder sintering device so as to change powders or a power compact into blocks. The reflector leads the neutrons deviated from the main axis back. The thermal neutron absorber is used for absorbing thermal neutrons so as to avoid overdosing in superficial normal tissue during therapy. The radiation shield is used for shielding leaking neutrons and photons so as to reduce dose of the normal tissue not exposed to irradiation.

Abstract: A beam shaping assembly for neutron capture therapy includes a beam inlet, a target having nuclear reaction with an incident proton beam from the beam inlet to produce neutrons forming a neutron beam, a moderator adjoining to the target, a reflector surrounding the moderator, a thermal neutron absorber adjoining to the moderator, a radiation shield arranged inside the beam shaping assembly and a beam outlet. The material of the moderator is subjected to a powder sintering process using a powder sintering device so as to change powders or a power compact into blocks. The reflector leads the neutrons deviated from the main axis back. The thermal neutron absorber is used for absorbing thermal neutrons so as to avoid overdosing in superficial normal tissue during therapy. The radiation shield is used for shielding leaking neutrons and photons so as to reduce dose of the normal tissue not exposed to irradiation.

Abstract: Abeam shaping assembly for neutron capture therapy includes a beam inlet, a target having nuclear reaction with an incident proton beam from the beam inlet to produce neutrons forming a neutron beam defining a main axis, a moderator adjoining to the target, a reflector surrounding the moderator, a thermal neutron absorber adjoining to the moderator, a radiation shield arranged inside the beam shaping assembly and a beam outlet. The neutrons are moderated to epithermal neutron energies. The reflector leads the neutrons deviated from the main axis back, and a gap channel is arranged between the moderator and the reflector. The thermal neutron absorber is used for absorbing thermal neutrons so as to avoid overdosing in superficial normal tissue during therapy. The radiation shield is used for shielding leaking neutrons and photons so as to reduce dose of the normal tissue not exposed to irradiation.

Abstract: A beam shaping assembly for neutron capture therapy includes a beam inlet, a target having nuclear reaction with an incident proton beam from the beam inlet to produce neutrons forming a neutron beam, a moderator adjoining to the target, a reflector surrounding the moderator, a thermal neutron absorber adjoining to the moderator, a radiation shield arranged inside the beam shaping assembly and a beam outlet. The material of the moderator is subjected to a powder sintering process using a powder sintering device so as to change powders or a power compact into blocks. The reflector leads the neutrons deviated from the main axis back. The thermal neutron absorber is used for absorbing thermal neutrons so as to avoid overdosing in superficial normal tissue during therapy. The radiation shield is used for shielding leaking neutrons and photons so as to reduce dose of the normal tissue not exposed to irradiation.

Abstract: An expander includes a first handle, a second handle, a first supporting member, and a second supporting member. The first handle includes a first gripping portion, a first pivoting portion, a first connecting portion, and an expanding compass. The second handle includes a second gripping portion, a second pivoting portion, and a second connecting portion. The second gripping portion includes a thru groove, and the expanding compass passes through the thru groove. The second pivoting portion is pivoted to the first pivoting portion. The second connecting portion and the second gripping portion are extending from two ends of the second pivoting portion, and the extension direction of the second connecting portion is not parallel to the extension direction of the second gripping portion.

Abstract: Disclosed is a beam shaping assembly, including a beam inlet; a target, wherein the target has nuclear reaction with the incident proton beam; a moderator adjoining to the target, wherein the neutrons are moderated by the moderator to epithermal neutrons; a reflector surrounding the moderator, and leads the deflected neutrons back to the moderator to enhance the epithermal neutron beam intensity; and a cooling system, wherein the cooling system comprises a first cooling part for cooling target, a second cooling part and a third cooling part connecting with the first cooling part and extending in a direction parallel to the axis of the accelerating tube respectively, the first cooling part connects with the target in a face to face manner, the cooling medium is inputted into the first cooling part from the second cooling part and is outputted from first cooling part through the third cooling part.

Abstract: The invention relates to antibody fusion proteins. Particularly, the invention relates to antibody fusion proteins for intra-cellular and intra-nucleus drugs delivery. The fusion protein of the invention can be used as a peptide penetration system that specifically binds to various targets for the delivery of effector peptides across a biological barrier.

Abstract: An oral dilator includes a first body, a second body, a rotary member, and a positioning member. The first body includes a housing and a first duckbilled element. The second body includes a second duckbilled element corresponding to the first duckbilled element. The rotary member drives the second body to rotate. The positioning member is on the first body and selectively locks or unlocks the relative position between the first duckbilled element and the second duckbilled element when the second duckbilled element is driven to rotate by the rotary member.

Abstract: A beam shaping assembly for neutron capture therapy includes a beam inlet, a target having nuclear reaction with an incident proton beam from the beam inlet to produce neutrons forming a neutron beam, a moderator adjoining to the target, a reflector surrounding the moderator, a thermal neutron absorber adjoining to the moderator, a radiation shield arranged inside the beam shaping assembly and a beam outlet. The material of the moderator is subjected to a powder sintering process using a powder sintering device so as to change powders or a power compact into blocks. The reflector leads the neutrons deviated from the main axis back. The thermal neutron absorber is used for absorbing thermal neutrons so as to avoid overdosing in superficial normal tissue during therapy. The radiation shield is used for shielding leaking neutrons and photons so as to reduce dose of the normal tissue not exposed to irradiation.

Abstract: Abeam shaping assembly for neutron capture therapy includes a beam inlet, a target having nuclear reaction with an incident proton beam from the beam inlet to produce neutrons forming a neutron beam defining a main axis, a moderator adjoining to the target, a reflector surrounding the moderator, a thermal neutron absorber adjoining to the moderator, a radiation shield arranged inside the beam shaping assembly and a beam outlet. The neutrons are moderated to epithermal neutron energies. The reflector leads the neutrons deviated from the main axis back, and a gap channel is arranged between the moderator and the reflector. The thermal neutron absorber is used for absorbing thermal neutrons so as to avoid overdosing in superficial normal tissue during therapy. The radiation shield is used for shielding leaking neutrons and photons so as to reduce dose of the normal tissue not exposed to irradiation.

Abstract: A beam shaping assembly for neutron capture therapy includes a beam inlet, a target having nuclear reaction with an incident proton beam from the beam inlet to produce neutrons forming a neutron beam defining a main axis, a moderator adjoining to the target, a reflector surrounding the moderator, a thermal neutron absorber adjoining to the moderator, a radiation shield arranged inside the beam shaping assembly and a beam outlet. The neutrons are moderated to epithermal neutron energies. The reflector leads the neutrons deviated from the main axis back, and a gap channel is arranged between the moderator and the reflector. The thermal neutron absorber is used for absorbing thermal neutrons so as to avoid overdosing in superficial normal tissue during therapy. The radiation shield is used for shielding leaking neutrons and photons so as to reduce dose of the normal tissue not exposed to irradiation.

Abstract: Disclosed is a beam shaping assembly, including a beam inlet; a target, wherein the target has nuclear reaction with the incident proton beam; a moderator adjoining to the target, wherein the neutrons are moderated by the moderator to epithermal neutrons; a reflector surrounding the moderator, and leads the deflected neutrons back to the moderator to enhance the epithermal neutron beam intensity; and a cooling system, wherein the cooling system comprises a first cooling part for cooling target, a second cooling part and a third cooling part connecting with the first cooling part and extending in a direction parallel to the axis of the accelerating tube respectively, the first cooling part connects with the target in a face to face manner, the cooling medium is inputted into the first cooling part from the second cooling part and is outputted from first cooling part through the third cooling part.