Patents by Inventor PEI-HSIN LIN

PEI-HSIN LIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12636292
    Abstract: The present invention pertains to a method for alleviating atherosclerosis in a subject comprising administrating to said subject a composition or pharmaceutical composition comprising Antcin K.
    Type: Grant
    Filed: January 10, 2024
    Date of Patent: May 26, 2026
    Assignee: ARJIL BIOTECH HOLDING COMPANY LIMITED
    Inventors: Yeh B Wu, Jir-Mehng Lo, Hui Ju Liang, Pei-Hsin Lin, Chieh-Hsi Wu, Chung-Hsin Wu
  • Patent number: 12582689
    Abstract: The present invention relates to a method of preventing or treating a fibrotic condition, comprising administering an effective amount of composition to a subject in need thereof; wherein the composition comprises triterpenes extracted from Antrodia-camphorate or Anisomeles indica.
    Type: Grant
    Filed: May 19, 2021
    Date of Patent: March 24, 2026
    Assignee: ARJIL BIOTECH HOLDING COMPANY LIMITED
    Inventors: Yeh-B Wu, Jir-Mehng Lo, Hui-Ju Liang, Pei-Hsin Lin
  • Patent number: 12433901
    Abstract: The present invention pertains to anti-coronaviral compounds. The disclosure includes a method for preventing and/or treating a coronavirus infection through the inhibition of a cysteine protease in a virus, particularly SARS-COV-2. Also provided includes the composition/pharmaceutical composition for preventing and/or treating a coronavirus infection comprising any of the compounds, pharmaceutically acceptable salt thereof, or its mixture, and the use of the compounds.
    Type: Grant
    Filed: April 30, 2021
    Date of Patent: October 7, 2025
    Assignee: ARJIL BIOTECH HOLDING COMPANY LIMITED
    Inventors: Jir-Mehng Lo, Cheng Huang, Yeh B Wu, Hui-Ju Liang, Pei-Hsin Lin, Hao Chiang, Wei-Chung Chiou
  • Patent number: 12364731
    Abstract: A method of treating or alleviating autoimmune-related diseases is provided. The method includes administering a pharmaceutical composition to a subject in need thereof. Moreover, the pharmaceutical composition includes an extract of Amomum tsao-ko as an effective ingredient and a pharmaceutically acceptable carrier or salt.
    Type: Grant
    Filed: October 31, 2022
    Date of Patent: July 22, 2025
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Kuo-Kuei Huang, I-Horng Pan, Meng-Nan Lin, Jir-Mehng Lo, Jennline Sheu, Pei-Ru Liau, Yi-Cheng Cheng, Pei-Hsin Lin
  • Publication number: 20240374616
    Abstract: The present invention relates to a method of treating mast cell tumor, comprising administering an effective amount of composition to a subject in need thereof: wherein the composition comprises terpenoids extracted from Antrodia camphorate or Anisomeles indica.
    Type: Application
    Filed: September 13, 2022
    Publication date: November 14, 2024
    Applicant: ARJIL BIOTECH HOLDING COMPANY LIMITED
    Inventors: Yeh B Wu, Jir-Mehng Lo, Hui Ju Liang, Pei-Hsin Lin
  • Publication number: 20240252515
    Abstract: The present invention relates to a method of preventing or treating a fibrotic condition, comprising administering an effective amount of composition to a subject in need thereof; wherein the composition comprises triterpenes extracted from antrodia camphorate or Anisomeles indica.
    Type: Application
    Filed: January 19, 2024
    Publication date: August 1, 2024
    Applicant: ARJIL BIOTECH HOLDING COMPANY LIMITED
    Inventors: Yeh B WU, Jir-Mehng LO, Hui-Ju LIANG, Pei-Hsin LIN, Kuo-Kuei HUANG
  • Publication number: 20240148753
    Abstract: The present invention pertains to a method for alleviating atherosclerosis in a subject comprising administrating to said subject a composition or pharmaceutical composition comprising Antcin K.
    Type: Application
    Filed: January 10, 2024
    Publication date: May 9, 2024
    Applicant: ARJIL BIOTECH HOLDING COMPANY LIMITED
    Inventors: Yeh B WU, Jir-Mehng LO, Hui Ju LIANG, Pei-Hsin LIN, Chieh-Hsi WU, Chung-Hsin WU
  • Publication number: 20230346737
    Abstract: The present invention pertains to anti viral compounds. The disclosure includes a method for preventing and/or treating a virus infection through the inhibition of a cysteine protease in a virus and/or a sodium taurocholate cotransporting polypeptide in a cell, particularly SARS-COV-2 and hepatitis B virus (HBV). Also provided includes the composition/pharmaceutical composition for preventing and/or treating a virus infection comprising any of the compounds, pharmaceutically acceptable salt thereof, or its mixture, and the use of the compounds.
    Type: Application
    Filed: August 27, 2021
    Publication date: November 2, 2023
    Applicant: ARJIL BIOTECH HOLDING COMPANY LIMITED
    Inventors: Yeh B WU, Jir-Mehng LO, Cheng HUANG, Hui-Ju LIANG, Pei-Hsin LIN, Hao CHIANG, Wei-Chung CHIOU, Guan-Jhong HUANG
  • Publication number: 20230201221
    Abstract: The present invention relates to a method of preventing or treating a fibrotic condition, comprising administering an effective amount of composition to a subject in need thereof; wherein the composition comprises triterpenes extracted from Antrodia camphorate or Anisomeles indica.
    Type: Application
    Filed: May 19, 2021
    Publication date: June 29, 2023
    Applicant: ARJIL BIOTECH HOLDING COMPANY LIMITED
    Inventors: Yeh-B WU, Jir-Mehng LO, Hui-Ju LIANG, Pei-Hsin LIN
  • Publication number: 20230190850
    Abstract: The present invention relates to a method of preventing or treating a fibrotic condition, comprising administering an effective amount of composition to a subject in need thereof; wherein the composition comprises triterpenes extracted from Antrodia-camphorate or anisomeles indica.
    Type: Application
    Filed: May 19, 2021
    Publication date: June 22, 2023
    Applicant: ARJIL BIOTECH HOLDING COMPANY LIMITED
    Inventors: Yeh-B WU, Jir-Mehng LO, Hui-Ju LIANG, Pei-Hsin LIN
  • Publication number: 20230061259
    Abstract: A method of treating or alleviating autoimmune-related diseases is provided. The method includes administering a pharmaceutical composition to a subject in need thereof. Moreover, the pharmaceutical composition includes an extract of Amomum tsao-ko as an effective ingredient and a pharmaceutically acceptable carrier or salt.
    Type: Application
    Filed: October 31, 2022
    Publication date: March 2, 2023
    Applicant: Industrial Technology Research Institute
    Inventors: Kuo-Kuei HUANG, I-Horng PAN, Meng-Nan LIN, Jir-Mehng LO, Jennline SHEU, Pei-Ru LIAU, Yi-Cheng CHENG, Pei-Hsin LIN
  • Publication number: 20230041859
    Abstract: The present invention relates to a method of preventing or treating a fibrotic condition, comprising administering an effective amount of composition to a subject in need thereof; wherein the composition comprises triterpenes extracted from Antrodia camphorate or Anisomeles indica.
    Type: Application
    Filed: July 1, 2021
    Publication date: February 9, 2023
    Inventors: Yeh-B WU, Jir-Mehng LO, Hui-Ju LIANG, Pei-Hsin LIN, Kuo-Kuei HUANG
  • Patent number: 11510957
    Abstract: A method of treating or alleviating autoimmune-related diseases is provided. The method comprises administering a pharmaceutical composition to a subject in need thereof. Moreover, the pharmaceutical composition comprises an extract of Amomum tsao-ko as an effective ingredient and a pharmaceutically acceptable carrier or salt.
    Type: Grant
    Filed: November 27, 2019
    Date of Patent: November 29, 2022
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Kuo-Kuei Huang, I-Horng Pan, Meng-Nan Lin, Jir-Mehng Lo, Jennline Sheu, Pei-Ru Liau, Yi-Cheng Cheng, Pei-Hsin Lin
  • Publication number: 20220249395
    Abstract: A method for treating an autoimmune neurological disease and/or a neurodegenerative disease is provided. The method includes administering an effective amount of at least one compound having Formula (I), Formula (II) or Formula (III), or its geometric isomer, enantiomer or diastereomer to a subject in need thereof: wherein is a single or double bond, X is NCH3 or CH2, Y is null, O or N, Z is O or N, R1 is H, OH, and R2 is null, H, C1-C8 alkyl, —(C?O)-alkyl, —(C?O)-aryl, —(C?O)-alkyl-aryl, —(C?O)-heteroaryl, cycloalkyl or heterocycloalkyl, which optionally substituted by one or more of —OH, —NO2, —NH2, —NR3R4, carbonyl, alkoxyl, alkyl or —OCF3, wherein R3 and R4 independently are H, alkyl, O2CH3, —(C?O)—CH3 or (C?O)—NH2.
    Type: Application
    Filed: April 22, 2022
    Publication date: August 11, 2022
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Kuo-Kuei HUANG, I-Hong PAN, Shu-Fang WEN, Meng-Nan LIN, I-Huang LU, Zong-Keng KUO, Chu-Hsun LU, Tze-Chung LEE, Ya-Yan YANG, Jia-Horng LIAW, Pei-Hsin LIN
  • Patent number: 11400054
    Abstract: A method for treating an autoimmune neurological disease and/or a neurodegenerative disease is provided. The method includes administering an effective amount of at least one compound having Formula (I), Formula (II) or Formula (III), or its geometric isomer, enantiomer or diastereomer to a subject in need thereof: wherein is a single or double bond, X is NCH3 or CH2, Y is null, O or N, Z is O or N, R1 is H, OH, and R2 is null, H, C1-C8 alkyl, —(C?O)-alkyl, —(C?O)-aryl, —(C?O)-alkyl-aryl, —(C?O)-heteroaryl, cycloalkyl or heterocycloalkyl, which optionally substituted by one or more of —OH, —NO2, —NH2, —NR3R4, carbonyl, alkoxyl, alkyl or —OCF3, wherein R3 and R4 independently are H, alkyl, —SO2CH3, —(C?O)—CH3 or —(C?O)—NH2.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: August 2, 2022
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Kuo-Kuei Huang, I-Hong Pan, Shu-Fang Wen, Meng-Nan Lin, I-Huang Lu, Zong-Keng Kuo, Chu-Hsun Lu, Tze-Chung Lee, Ya-Yan Yang, Jia-Horng Liaw, Pei-Hsin Lin
  • Patent number: 11253527
    Abstract: The present invention pertains to a composition for preparing a medicament for preventing and/or treating a virus infection, especially a hepatitis B virus infection and/or a herpes simplex virus, and uses thereof.
    Type: Grant
    Filed: February 25, 2020
    Date of Patent: February 22, 2022
    Assignee: ARJIL BIOTECH HOLDING COMPANY LIMITED
    Inventors: Yeh B Wu, Jir-Mehng Lo, Hui Ju Liang, Pei-Hsin Lin, Cheng Huang
  • Publication number: 20210338690
    Abstract: The present invention pertains to anti-coronaviral compounds. The disclosure includes a method for preventing and/or treating a coronavirus infection through the inhibition of a cysteine protease in a virus, particularly SARS-COV-2. Also provided includes the composition/pharmaceutical composition for preventing and/or treating a coronavirus infection comprising any of the compounds, pharmaceutically acceptable salt thereof, or its mixture, and the use of the compounds.
    Type: Application
    Filed: April 30, 2021
    Publication date: November 4, 2021
    Applicant: ARJIL BIOTECH HOLDING COMPANY LIMITED
    Inventors: Jir-Mehng LO, Cheng HUANG, Yeh B WU, Hui-Ju LIANG, Pei-Hsin LIN, Hao CHIANG, Wei-Chung CHIOU
  • Publication number: 20200330485
    Abstract: The present invention pertains to a method for inhibiting, reducing or reversing atherosclerosis or a composition or pharmaceutical composition for preventing or treating an atherosclerotic disease containing a preparation of Antrodia camphorata, and/or one or more active compounds isolated form Antrodia camphorataa.
    Type: Application
    Filed: April 17, 2020
    Publication date: October 22, 2020
    Applicant: ARJIL BIOTECH HOLDING COMPANY LIMITED
    Inventors: Yeh B Wu, Jir-Mehng Lo, Hui Ju Liang, Pei-Hsin Lin, Chieh-Hsi Wu
  • Publication number: 20200268771
    Abstract: The present invention pertains to a composition for preparing a medicament for preventing and/or treating a virus infection, especially a hepatitis B virus infection and/or a herpes simplex virus, and uses thereof.
    Type: Application
    Filed: February 25, 2020
    Publication date: August 27, 2020
    Applicant: ARJIL BIOTECH HOLDING COMPANY LIMITED
    Inventors: Yeh B Wu, Jir-Mehng Lo, Hui Ju Liang, Pei-Hsin Lin, Cheng Huang
  • Patent number: 10688078
    Abstract: The invention relates to a use of a compound for manufacturing a medicament for treating an allergic disease, wherein the compound is selected from the group consisting of ovatodiolide, 1?-acetoxychavicol acetate, zerumbone and combination thereof. Also provided is a method and a composition for treating an allergic disease.
    Type: Grant
    Filed: July 8, 2019
    Date of Patent: June 23, 2020
    Assignee: ARJIL BIOTECH HOLDING COMPANY LIMITED
    Inventors: Yeh B Wu, Jir-Mehng Lo, Hui Ju Liang, Pei-Hsin Lin