Patents by Inventor Peijun Cong
Peijun Cong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7728309Abstract: The present invention discloses a high throughput screening method and system, which can be used to screen a plurality of fluid samples to ascertain their corresponding information. For example, a polymer solution sample is screened to ascertain information about its micro structure character such as including its crystallinity property. The high throughput screen system comprises a plurality of sampling passages and one or more screening devices for screening multiple samples simultaneously or almost simultaneously to get their corresponding information so as to meet research requirement of the relevant field.Type: GrantFiled: May 11, 2006Date of Patent: June 1, 2010Assignee: Yashentech CorporationInventors: Peijun Cong, Zhuo Wang, Youqi Wang
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Publication number: 20100080733Abstract: A needle assembly has at least one guide member supported by a first body for sliding movement between an extended position and a retracted position. A second body is attached to the guide member. A biasing member biases the guide member to the extended position. A liquid handling needle is coupled to the first body so sliding movement of the guide member toward the retracted position retracts the second body relative to the liquid handling needle. The second body is adapted to contact a sealed receptacle. The biasing member urges the guide member toward said extended position during insertion and during said removal of the needle from the receptacle whereby the second body remains in contact with the sealed receptacle as the guide member moves from its extended position to its retracted position during said insertion and from its retracted position to its extended position during said removal.Type: ApplicationFiled: June 22, 2009Publication date: April 1, 2010Applicant: SYMYX TECHNOLOGIES, INC.Inventors: Eric D. Carlson, Peijun Cong, William H. Chandler, JR., Peter J. Desrosiers, J. Christopher Freitag, John F. Varni
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Patent number: 7549978Abstract: A needle assembly has a first body and a guide rod supported for sliding movement between an extended position and a retracted position. A second body is attached to the guide rod. The second body is relatively farther from the first body when the guide rod is in the extended position and relatively closer to the first body when the guide rod is in the retracted position. The guide rod is biased to the extended position. The second body supports a venting needle that extends beyond the second body by a fixed length. A liquid handling needle is coupled to the first body. Sliding movement of the guide rod toward the retracted position retracts the second body and the venting needle relative to the liquid handling needle.Type: GrantFiled: May 16, 2005Date of Patent: June 23, 2009Assignee: Symyx Technologies, Inc.Inventors: Eric D. Carlson, Peijun Cong, William H. Chandler, Jr., Peter J. Desrosiers, J. Christopher Freitag, John F. Varni
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Publication number: 20080191147Abstract: The present invention discloses a high throughput screening method and system, which can be used to screen a plurality of fluid samples to ascertain their corresponding information. For example, a polymer solution sample is screened to ascertain information about its micro structure character such as including its crystallinity property. The high throughput screen system comprises a plurality of sampling passages and one or more screening devices for screening multiple samples simultaneously or almost simultaneously to get their corresponding information so as to meet research requirement of the relevant field.Type: ApplicationFiled: May 11, 2006Publication date: August 14, 2008Inventors: Peijun Cong, Zhuo Wang, Youqi Wang
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Publication number: 20080159064Abstract: The present invention discloses an apparatus for processing materials, which is used to process the materials introduced thereinto, comprising a working part and a driving part, wherein the working part comprises, in cylindrical form, a first element and a second element arranged within the first element, and a containing chamber for storing materials to be processed being formed by the gap between the first element and the second element, and the second element is driven by the driving part to rotate relatively to the first element, and on the surface of the second element toward the containing chamber, provided is a disturbing part capable of producing axial forces in a direction parallel to the axis of the first element.Type: ApplicationFiled: December 13, 2005Publication date: July 3, 2008Inventors: Youqi Wang, Peijun Cong, Guilin Wang, Wenhui Wang, Lichen Diao, Youshu Kang, Yubin Zhong, Bohejin Tang, Fuxin Huang
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Patent number: 7255474Abstract: A library of material samples is provided in a condition suitable for imaging using infrared (IR) spectroscopy. The samples are provided to one or more detection cells, each of the cells including or containing a reflective surface. Preferably, for imaging, an energy source (e.g. a source of infrared radiation) provides energy to the detection cells to interact with the samples. Thereafter, images (e.g., spectra) related to the samples are created based upon the interaction.Type: GrantFiled: July 28, 2004Date of Patent: August 14, 2007Assignee: Symyx Technologies, Inc.Inventors: Peijun Cong, Shenheng Guan, Stephen Cypes, Jason Wells, H. Sam Bergh
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Publication number: 20070077657Abstract: The invention provides methods, apparatus, and systems for performing high-throughput preparation and screening of salts and polymorphs of drug candidates. The invention is directed towards enhancing the pre-formulation discovery process used for drug development. In particular, processes that determine suitable salts and processes that discover substantially every polymorph that can form from a particular drug candidate are provided. The processes are performed using several apparatuses that are specifically configured to carry-out various steps in a high-throughput characterization process. One such apparatus is configured for synthesizing a plurality of library members based on, for example, a library model generated by a computer system. Another apparatus may filter the synthesized solution to provide a substantially pure mixture that can be subjected to salt or polymorph testing.Type: ApplicationFiled: March 24, 2006Publication date: April 5, 2007Applicant: Symyx Technologies, Inc.Inventors: Eric Carlson, Peijun Cong, William Chandler, Henry Chau, Earl Danielson, Peter Desrosiers, Robert Doolen, Luping Wu, C. Ramberg, Thomas Crevier, Ralph Nielsen, Colin Masui, John Varni
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Patent number: 7071000Abstract: A method for sampling reaction products includes delivering a reactant through a sampling probe to contact a substance deposited on a substrate and reacting the reactant to form a reaction product. At least a portion of the reaction product is withdrawn through the sampling probe and analyzed. The sampling probe is contacted with the substrate during at least a portion of the delivering, reacting and withdrawing steps.Type: GrantFiled: December 30, 2002Date of Patent: July 4, 2006Assignee: Symyx Technologies, Inc.Inventors: Youqi Wang, Peijun Cong, Tony N. Wheeler, Lynn Thomas Van Erden, H. Sam Bergh
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Publication number: 20050211622Abstract: The invention provides methods, apparatus, and systems for performing high-throughput preparation and screening of salts and polymorphs of drug candidates. The invention is directed towards enhancing the pre-formulation discovery process used for drug development. In particular, processes that determine suitable salts and processes that discover substantially every polymorph that can form from a particular drug candidate are provided. The processes are performed using several apparatuses that are specifically configured to carry-out various steps in a high-throughput characterization process. One such apparatus is configured for synthesizing a plurality of library members based on, for example, a library model generated by a computer system. Another apparatus may filter the synthesized solution to provide a substantially pure mixture that can be subjected to salt or polymorph testing.Type: ApplicationFiled: May 16, 2005Publication date: September 29, 2005Applicant: Symyx Technologies, Inc.Inventors: Eric Carlson, Peijun Cong, William Chandler, Peter Desrosiers, J. Freitag, John Varni
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Patent number: 6939515Abstract: The invention provides methods, apparatus, and systems for performing high-throughput preparation and screening of salts and polymorphs of drug candidates. The invention is directed towards enhancing the pre-formulation discovery process used for drug development. In particular, processes that determine suitable salts and processes that discover substantially every polymorph that can form from a particular drug candidate are provided. The processes are performed using several apparatuses that are specifically configured to carry-out various steps in a high-throughput characterization process. One such apparatus is configured for synthesizing a plurality of library members based on, for example, a library model generated by a computer system. Another apparatus may filter the synthesized solution to provide a substantially pure mixture that can be subjected to salt or polymorph testing.Type: GrantFiled: May 24, 2002Date of Patent: September 6, 2005Assignee: Symyx Technologies, Inc.Inventors: Eric D. Carlson, Peijun Cong, William H. Chandler, Jr., Peter J. Desrosiers, J. Christopher Freitag, John F. Varni
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Publication number: 20050056787Abstract: A library of material samples is provided in a condition suitable for imaging using infrared (IR) spectroscopy. The samples are provided to one or more detection cells, each of the cells including or containing a reflective surface. Preferably, for imaging, an energy source (e.g. a source of infrared radiation) provides energy to the detection cells to interact with the samples. Thereafter, images (e.g., spectra) related to the samples are created based upon the interaction.Type: ApplicationFiled: July 28, 2004Publication date: March 17, 2005Inventors: Peijun Cong, Shenheng Guan, Stephen Cypes, Jason Wells, H. Bergh
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Patent number: 6864091Abstract: A sampling probe for delivering a reactant to a substance deposited on a substrate to form a reaction product and for transporting the reaction product to a product analyzer for analysis. The probe includes a tip positionable over the substance on the substrate. The probe has a recess in the tip sized and shaped for receiving at least a portion of the reaction product. The probe has a product sampling passage extending from the recess adapted for connection to the product analyzer for transporting the portion of the reaction product to the product analyzer. Further, a reactant delivery passage extends to an outlet at the recess for delivering reactant to the substance on the substrate to form the reaction product.Type: GrantFiled: August 31, 2000Date of Patent: March 8, 2005Assignee: Symyx Technologies, Inc.Inventors: Youqi Wang, Peijun Cong, Tony N. Wheeler, Lynn Thomas Van Erden, H. Sam Bergh
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Patent number: 6799629Abstract: Apparatus for cooling a bundle of capillary tubes to prevent overheating of the tubes during a parallel capillary electrophoresis procedure. The apparatus includes a jacket of thermally conductive solid material comprising mating jacket members movable between an open position in which the jacket members are separated to allow placement of the bundle in the jacket and a closed position in which the jacket members are mated together and the bundle is disposed inside the jacket in thermally conductive relation with the jacket. Window openings in the mating jacket members define a window to permit the passage of light through the window and the capillary tubes of the bundle at the location of the window.Type: GrantFiled: May 9, 2001Date of Patent: October 5, 2004Assignee: Symyx Technologies, Inc.Inventors: Peijun Cong, Robert D. Doolen, Tony N. Wheeler
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Publication number: 20030201181Abstract: A hydrodynamic injector for substantially concurrently loading fluid samples to be analyzed into multiple capillary tubes of a capillary electrophoresis system. The injector includes an enclosure defining a pressure chamber for holding multiple receptacles, each containing a fluid sample, and apertures in the enclosure for passing capillary tubes into a position inside the pressure chamber and in fluid communication with the samples in respective receptacles. Electrodes on the enclosure extend into the pressure chamber for reception in the receptacles. The pressure chamber is pressurized with gas to substantially concurrently force the fluid samples from respective receptacles into the capillary tubes in preparation for a capillary electrophoresis operation.Type: ApplicationFiled: May 12, 2003Publication date: October 30, 2003Applicant: Symyx Technologies, Inc.Inventors: Peijun Cong, Robert D. Doolen, Tony N. Wheeler
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Publication number: 20030146096Abstract: A multiplexed capillary electrophoresis system with cooling sufficient to prevent overheating during chiral separation. The system includes a thermally insulated enclosure enclosing a bundle of capillary tubes, a light source and photodetector. A heat transfer system is provided for cooling closely spaced portions and spread apart portions of the capillary tubes to an extent sufficient to prevent overheating of the tubes and contents thereof due to the heat generated during chiral separation.Type: ApplicationFiled: February 13, 2003Publication date: August 7, 2003Applicant: Symyx Technologies, Inc.Inventors: Peijun Cong, Robert D. Doolen
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Publication number: 20030124028Abstract: The invention provides methods, apparatus, and systems for performing high-throughput preparation and screening of salts and polymorphs of drug candidates. The invention is directed towards enhancing the pre-formulation discovery process used for drug development. In particular, processes that determine suitable salts and processes that discover substantially every polymorph that can form from a particular drug candidate are provided. The processes are performed using several apparatuses that are specifically configured to carry-out various steps in a high-throughput characterization process. One such apparatus is configured for synthesizing a plurality of library members based on, for example, a library model generated by a computer system. Another apparatus may filter the synthesized solution to provide a substantially pure mixture that can be subjected to salt or polymorph testing.Type: ApplicationFiled: May 24, 2002Publication date: July 3, 2003Inventors: Eric D. Carlson, Peijun Cong, William H. Chandler, Henry K. Chau, Earl Danielson, Peter J. Desrosiers, Robert D. Doolen, Luping Wu, C. Eric Ramberg, Thomas Crevier, Ralph B. Nielsen, Colin S. Masui, John F. Varni
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Publication number: 20030118078Abstract: The invention provides methods, apparatus, and systems for performing high-throughput preparation and screening of salts and polymorphs of drug candidates. The invention is directed towards enhancing the pre-formulation discovery process used for drug development. In particular, processes that determine suitable salts and processes that discover substantially every polymorph that can form from a particular drug candidate are provided. The processes are performed using several apparatuses that are specifically configured to carry-out various steps in a high-throughput characterization process. One such apparatus is configured for synthesizing a plurality of library members based on, for example, a library model generated by a computer system. Another apparatus may filter the synthesized solution to provide a substantially pure mixture that can be subjected to salt or polymorph testing.Type: ApplicationFiled: May 24, 2002Publication date: June 26, 2003Inventors: Eric D. Carlson, Peijun Cong, William H. Chandler, Peter J. Desrosiers, Robert D. Doolen, J. Christopher Freitag
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Publication number: 20030116497Abstract: The invention provides methods, apparatus, and systems for performing high-throughput preparation and screening of salts and polymorphs of drug candidates. The invention is directed towards enhancing the pre-formulation discovery process used for drug development. In particular, processes that determine suitable salts and processes that discover substantially every polymorph that can form from a particular drug candidate are provided. The processes are performed using several apparatuses that are specifically configured to carry-out various steps in a high-throughput characterization process. One such apparatus is configured for synthesizing a plurality of library members based on, for example, a library model generated by a computer system. Another apparatus may filter the synthesized solution to provide a substantially pure mixture that can be subjected to salt or polymorph testing.Type: ApplicationFiled: May 24, 2002Publication date: June 26, 2003Inventors: Eric D. Carlson, Peijun Cong, William H. Chandler, Peter J. Desrosiers, J. Christopher Freitag, John F. Varni
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Patent number: 6572750Abstract: A hydrodynamic injector for substantially concurrently loading fluid samples to be analyzed into multiple capillary tubes of a capillary electrophoresis system. The injector includes an enclosure defining a pressure chamber for holding multiple receptacles, each containing a fluid sample, and apertures in the enclosure for passing capillary tubes into a position inside the pressure chamber and in fluid communication with the samples in respective receptacles. Electrodes on the enclosure extend into the pressure chamber for reception in the receptacles. The pressure chamber is pressurized with gas to substantially concurrently force the fluid samples from respective receptacles into the capillary tubes in preparation for a capillary electrophoresis operation.Type: GrantFiled: July 21, 2000Date of Patent: June 3, 2003Assignee: Symyx Technologies, Inc.Inventors: Peijun Cong, Robert D. Doolen, Tony N. Wheeler
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Publication number: 20030100120Abstract: A method for sampling reaction products includes delivering a reactant through a sampling probe to contact a substance deposited on a substrate and reacting the reactant to form a reaction product. At least a portion of the reaction product is withdrawn through the sampling probe and analyzed. The sampling probe is contacted with the substrate during at least a portion of the delivering, reacting and withdrawing steps.Type: ApplicationFiled: December 30, 2002Publication date: May 29, 2003Applicant: Symyx Technologies, Inc.Inventors: Youqi Wang, Peijun Cong, Tony N. Wheeler, Lynn Thomas Van Erden, H. Sam Bergh