Abstract: Use of bellidifolin (BEL) and/or a BEL-containing extract in preparation of an antidepressant product is provided, belonging to the technical field of medicine. The BEL or BEL-containing extract as an active ingredient can significantly improve a depressive behavior of mice, regulate concentrations of 5-hydroxytryptamine (HT) and corticosterone (CORT), protect nerve cells, and improve synaptic plasticity. Moreover, the BEL or BEL-containing extract can penetrate the blood-brain barrier (BBB) and has a significant effect on improving and treating depression. In addition, a method for preparing the BEL-containing extract has the advantages of simple operation, low cost, and desirable repeatability and stability. BEL in the extract has a concentration of up to 1.0% to 95.0%. After purifying the BEL-containing extract, the BEL has a high purity of up to 95.0% to 99.9%, and is easy to realize industrial production during the preparation.

Abstract: Provided for herein are pharmaceutical compositions comprising a therapeutic antibody and uses thereof for the treatment of C1s mediated disorders.

Abstract: The present disclosure belongs to the technical field of polymer rubber composites, and specifically relates to a rubber sealing gasket with excellent compression performance and low-temperature performance, and a preparation method and use thereof. The rubber sealing gasket is prepared from the following raw materials in parts by mass: a hydrogenated nitrile butadiene rubber (HNBR): 100 parts; a processing aid: 12.3 parts to 13.7 parts; a reinforcing filler: 45 parts to 65 parts; a vulcanizing agent: 4.8 parts to 5.2 parts; and a co-crosslinking agent: 4.8 parts to 5.2 parts. The rubber sealing gasket prepared by the present disclosure has excellent compression performance and low-temperature performance, meets the performance requirements of rubber sealing gaskets for automobile air-conditioning systems, and can be used in sealing components of automobile air-conditioning systems.

Abstract: An aqueous fire extinguishing agent and a preparation method thereof are provided, which are used for making a throw-type fire extinguisher. The aqueous fire extinguishing agent is composed of two compositions of A and B. The composition A is a fortified water added with a flame retardant (e.g., one or more of ammonium chloride, diammonium hydrogen phosphate and ammonium polyphosphate), a wetting agent (e.g., alkyl polyglycoside) and a colloid (e.g., polyacrylamide solution). The composition B is a regulator. After the composition A and the composition B are mixed, a discharge rate/speed of fire extinguishing substances is increased, so that an escape passage/route can be opened up quickly.

Abstract: Provided herein is a protective rubber track shoe for an excavator, which includes a first-stage rubber mix and a second-stage rubber mix. The first-stage rubber mix consists of a natural rubber, a chloroprene rubber, a butadiene rubber, a styrene-butadiene rubber, a tire reclaim rubber, a 120-mesh rubber powder, zinc oxide, stearic acid, an anti-aging agent 3100, an anti-aging agent CTU, paraffin wax, an intermediate super abrasion furnace carbon black and an aromatic oil. The second-stage rubber mix consists of the first-stage rubber mix, sulfur, an accelerator CZ and an auxiliary agent.

Abstract: The invention discloses a method for manufacturing a bulletproof and explosion-proof tubeless tire, first, the innerliner is attached to the carcass cord ply to make the carcass innerliner, and then the steel wire braided layers and the intermediate rubber layers are laminated to each other to make an explosion-proof layer, using a first stage building machine to complete the first stage forming of the carcass innerliner, explosion-proof layer and belt to obtain a semi-finished embryo, and then using a second stage building machine, the semi-finished embryo and the tread slab base are formed in the second stage to obtain the embryo, which is baked and stored for 8˜96h and then vulcanised to obtain a bulletproof and explosion-proof tire; through the second stage forming process, the invention solves the problem that the explosion-proof layer is difficult to form due to the excessively hard metal material when making the embryo.

Abstract: The present invention discloses a nucleic acids extraction system and method based on a 3D-printed microdevice, and belongs to the technical field of nucleic acids extraction. The nucleic acids extraction system is a monomer 3D-printed microdevice or a 3D-printed microdevice prepared by 3D printing technologies, the monomer 3D-printed microdevice comprises a nucleic acids binding region and a handle region, and the 3D-printed microdevice is composed of more than two monomer 3D-printed microdevices through a joining region; and the nucleic acids binding region is made of photosensitive resin or thermoplastic. An extraction method for the nucleic acids extraction system based on a 3D-printed microdevice is used to bind, clean and elute nucleic acids by moving the monomer 3D-printed microdevice or the 3D-printed microdevice among a solution containing target nucleic acids, a washing buffer and an elution buffer.

Abstract: The present disclosure relates to a submodule topology circuit for a modular multilevel converter and a method for controlling same. The submodule topology comprises an inlet port and an outlet port, at least two half-bridge submodules, a plurality of first switching devices, a plurality of thyristors and a plurality of diodes, wherein the at least two half-bridges are connected in series and are provided between the inlet port and the outlet port, and each of the half-bridge submodules is provided with an input port, a first output port and a second output port.

Abstract: The present disclosure relates to a submodule topology circuit for a modular multilevel converter and a method for controlling same. The submodule topology comprises an inlet port and an outlet port, at least two half-bridge submodules, a plurality of first switching devices, a plurality of thyristors and a plurality of diodes, wherein the at least two half-bridges are connected in series and are provided between the inlet port and the outlet port, and each of the half-bridge submodules is provided with an input port, a first output port and a second output port.

Abstract: An in-cavity cleaning method includes: a lower electrode temperature control step of controlling a lower electrode to a predetermined temperature; an electrode distance adjustment step of elevating the lower electrode and controlling a distance between an upper electrode and the lower electrode; a film deposition step of depositing a film on a substrate; a cleaning gas introducing step of introducing a cleaning gas in a plasma state from the upper electrode; and a cleaning gas pressure control step of adjusting a pressure of the cleaning gas in a cavity by adjusting an opening of a valve.

Abstract: An aqueous fire extinguishing agent and a preparation method thereof are provided, which are used for making a throw-type fire extinguisher. The aqueous fire extinguishing agent is composed of two compositions of A and B. The composition A is a fortified water added with a flame retardant (e.g., one or more of ammonium chloride, diammonium hydrogen phosphate and ammonium polyphosphate), a wetting agent (e.g., alkyl polyglycoside) and a colloid (e.g., polyacrylamide solution). The composition B is a regulator. After the composition A and the composition B are mixed, a discharge rate/speed of fire extinguishing substances is increased, so that an escape passage/route can be opened up quickly.

Abstract: Provided herein is a protective rubber track shoe for an excavator, which includes a first-stage rubber mix and a second-stage rubber mix. The first-stage rubber mix consists of a natural rubber, a chloroprene rubber, a butadiene rubber, a styrene-butadiene rubber, a tire reclaim rubber, a 120-mesh rubber powder, zinc oxide, stearic acid, an anti-aging agent 3100, an anti-aging agent CTU, paraffin wax, an intermediate super abrasion furnace carbon black and an aromatic oil. The second-stage rubber mix consists of the first-stage rubber mix, sulfur, an accelerator CZ and an auxiliary agent.

Abstract: The present invention discloses a preparation method of scribing rubber cement of a tire tread. The scribing rubber cement of the tire tread is prepared from the following raw materials in parts by weight: 100 parts of natural rubber; 3.5 to 4.5 parts of zinc oxide; 1.5 to 2.5 parts of stearic acid; 15 to 25 parts of titanium white; 2.5 to 3.5 parts of insoluble sulfur; 0.9 to 1.1 parts of accelerant DM; 0.9 to 1.1 parts of rosin; and 15 to 25 parts of color masterbatch. The preparation method of the scribing rubber cement comprises the following steps: step 1) preparing rubber compound; and step 2) preparing the scribing rubber cement. The scribing rubber cement of the tire tread prepared by the present invention has high aesthetic degree and does not influence the product quality.

Abstract: The present invention discloses a preparation method of scribing rubber cement of a tire tread. The scribing rubber cement of the tire tread is prepared from the following raw materials in parts by weight: 100 parts of natural rubber; 3.5 to 4.5 parts of zinc oxide; 1.5 to 2.5 parts of stearic acid; 15 to 25 parts of titanium white; 2.5 to 3.5 parts of insoluble sulfur; 0.9 to 1.1 parts of accelerant DM; 0.9 to 1.1 parts of rosin; and 15 to 25 parts of color masterbatch. The preparation method of the scribing rubber cement comprises the following steps: step 1) preparing rubber compound; and step 2) preparing the scribing rubber cement. The scribing rubber cement of the tire tread prepared by the present invention has high aesthetic degree and does not influence the product quality.

Abstract: Disclosed are a method of detecting a pre-determined event in a nucleic acid sample and a system thereof. The method of detecting the pre-determined event in the nucleic acid sample comprises the following steps: constructing a sequencing-library for the nucleic acid sample; sequencing the sequencing-library to obtain a sequencing result consisting of a plurality of sequencing data; determining the sequencing data from a pre-determined region; and determining an occurrence of the pre-determined event in the nucleic acid sample based on a composition of the sequencing data from the pre-determined region.

Abstract: The invention discloses a fault point locating method of hybrid lines based on analysis of comprehensive characteristics of single-end electric quantity and transient travelling waves, which mainly includes steps: phase-model transformation; looking up initial time of failure; extracting timing window data after the initial time; searching a reflected wave from the fault point and a reflected wave from a demarcation point in the timing window; and judging properties of the reflected waves. After failure of a hybrid line with cable and overhead line, by identifying and comparing comprehensive characteristics of the reflected wave from the fault point, primary and secondary reflected waves from the demarcation point in the single-end transient voltage and current travelling waves, it is rapidly judged whether the fault point is located in the overhead line segment or the cable segment, which is used to assist in switching decision for line reclosing.

Abstract: The invention discloses a fault point locating method of hybrid lines based on analysis of comprehensive characteristics of single-end electric quantity and transient travelling waves, which mainly includes steps: phase-model transformation; looking up initial time of failure; extracting timing window data after the initial time; searching a reflected wave from the fault point and a reflected wave from a demarcation point in the timing window; and judging properties of the reflected waves. After failure of a hybrid line with cable and overhead line, by identifying and comparing comprehensive characteristics of the reflected wave from the fault point, primary and secondary reflected waves from the demarcation point in the single-end transient voltage and current travelling waves, it is rapidly judged whether the fault point is located in the overhead line segment or the cable segment, which is used to assist in switching decision for line reclosing.

Abstract: Disclosed are a method of detecting a pre-determined event in a nucleic acid sample and a system thereof. The method of detecting the pre-determined event in the nucleic acid sample comprises the following steps: constructing a sequencing-library for the nucleic acid sample; sequencing the sequencing-library to obtain a sequencing result consisting of a plurality of sequencing data; determining the sequencing data from a pre-determined region; and determining an occurrence of the pre-determined event in the nucleic acid sample based on a composition of the sequencing data from the pre-determined region.

Abstract: The present invention involves an analysis method of cellular chromosomes, particularly involves a method of analyzing whether a difference exists in the chromosome number between amniotic cells and standard cells by a sequencing method.