Abstract: The present application provides a secondary battery, a battery module, a battery pack and an electrical device containing the same. The secondary battery comprises a positive electrode plate, and a non-aqueous electrolytic solution, wherein the positive electrode plate comprises a positive electrode active material with a core-shell structure, which comprises a core and a shell covering the core, in which the core has a chemical formula of Li1+xMn1-yAyP1-zRzO4, and the shell comprises a first cladding layer covering the core, a second cladding layer covering the first cladding layer and a third cladding layer covering the second cladding layer, and the non-aqueous electrolytic solution comprises a first additive comprising one or more of the compounds shown in Formula 1. The present application enables the secondary battery to simultaneously have high energy density with good rate performance, cycling performance, storage performance and safety performance.

Abstract: A high-nickel ternary positive electrode material, has a structural formula of LixNiaMbCocNzO2. A content of a cobalt element within a range of 1.5 ?m from a surface of the positive electrode material accounts for 48%-85% of a content of the cobalt element in the positive electrode material. A high-nickel ternary positive electrode material is designed in the present application, which has a specific structure with cobalt element distributed gradiently from inside to outside, and thus a high-nickel low-cobalt positive electrode material product with good stability can be directly obtained. The content of cobalt in the near-surface region and surface region of the positive electrode material is high, and high-content cobalt may react with Li+that cannot be re-inserted to generate lithium cobaltate. This increases part of the capacity and avoids the generation of residual alkali, thereby improving the capacity and cycle performance of the high-nickel ternary positive electrode material.

Abstract: The present disclosure provides a display panel. The display panel includes a base substrate, a first conductive layer and an active layer that are stacked in sequence. The first conductive layer includes a plurality of gate signal lines. The gate signal line includes a body part and a plurality of additional parts. An orthographic projection of the body part on the base substrate extends along a first direction. The plurality of additional parts are distributed at intervals in the first direction and coupled to a side of the body part in a second direction. The additional part is used to form a gate of a driving transistor. The active layer includes a plurality of active structures disposed corresponding to the plurality of additional parts. Orthographic projections of the plurality of active structures on the base substrate are separated from each other.

Abstract: Provided are a lithium secondary battery and an electric apparatus. The lithium secondary battery includes: a negative electrode plate, where the negative electrode plate includes a negative electrode current collector and a negative electrode active material layer disposed on at least one side of the negative electrode current collector, and a porosity of the negative electrode active material layer is P; and an electrolyte, where the electrolyte includes a solvent, the solvent includes at least one of compounds represented by the following formula (I), and a mass fraction of the compound represented by formula (I) in the solvent is W1, W1 and P satisfying 0.65?W1/P?4.4; where R1 and R2 each independently include at least one of an alkyl group having 1 to 3 carbon atoms and a halogenated alkyl group having 1 to 3 carbon atoms.

Abstract: This application provides a secondary battery. A negative active material thereof includes a graphite material. A non-aqueous electrolyte thereof includes chain carboxylate. An OI value of a negative electrode plate, a resistance value R of the negative electrode plate, and a mass percent W0 of a first solvent in a solvent satisfy 0.08/m??W0×100/(R×OI)?5/m?, where the OI value means a ratio of an intensity of a 004 crystal plane diffraction peak to an intensity of a 110 crystal plane diffraction peak of the graphite material, and R is in units of m?.

Abstract: This application relates to a lithium-ion battery having a cell group margin A of 88%-97% and including a non-aqueous electrolyte. The non-aqueous electrolyte includes one or more first organic solvents with a specified structure. Based on a total mass of an organic solvent in the non-aqueous electrolyte, a mass percentage of the first organic solvent is X1, X1 being in a range of 20%-80%, and the cell group margin A and the mass percentage X1 of the first organic solvent satisfy a specified relation: 0.22?X1/A?0.91. This application further relates to an electric apparatus including the lithium-ion battery.

Abstract: A secondary battery, a battery module, a battery pack, and an electric apparatus are provided. The secondary battery includes a positive electrode plate and a non-aqueous electrolyte. The positive electrode plate includes a positive electrode active material, the positive electrode active material including a core and a shell enveloping the core, where the core contains Li1+xMn1-yAyP1-zRzO4, and the shell includes a first coating layer enveloping the core and a second coating layer enveloping the first coating layer. The first coating layer includes a pyrophosphate MP2O7 and a phosphate XPO4, where M and X each are one or more independently selected from Li, Fe, Ni, Mg, Co, Cu, Zn, Ti, Ag, Zr, Nb, or Al; and the second coating layer contains carbon.

Abstract: The present application provides a secondary battery, and providing a battery module, a battery pack, and a powder device comprising the same. The secondary battery includes a positive electrode plate and a non-aqueous electrolytic solution, in which the positive electrode plate includes a positive electrode active material having a core-shell structure, the positive electrode active material includes an core and a shell covering the core, the core includes Li1+xMn1?yAyP1?zRzO4, the shell includes a first coating layer covering the core and a second coating layer covering the first coating layer, the non-aqueous electrolytic solution includes a first additive one or more selected from the compounds shown in formulae 1-A to 1-D. The secondary battery of the present application can have a relatively high energy density, and also a good rate performance, cycling performance, storage performance and safety performance.

Abstract: A bispecific antibody targeting both CD40 and CLDN18.2, a pharmaceutical composition comprising same, an application thereof for treating related diseases, and a treatment method are provided. The bispecific antibody targeting both CD40 and CLDN18.2 comprises (i) an anti-CD40 antibody or a fragment thereof and (ii) an anti-CLDN18.2 antibody or a fragment thereof.

Abstract: A scan circuit is provided. The scan circuit includes a plurality of stages. A respective stage of the scan circuit includes a respective scan unit configured to provide a control signal to one or more rows of subpixels. A respective scan unit includes a first subcircuit, a second subcircuit, a third subcircuit, a fourth subcircuit. A pull-up node is coupled to the second subcircuit, the third subcircuit, and the fourth subcircuit. A pull-down node is coupled to the second subcircuit, the third subcircuit. The denoising subcircuit is coupled to a pull-up node and the input terminal, or coupled between a third power supply voltage terminal and the pull-down control node.

Abstract: Methods, apparatuses and systems for providing a switching component are disclosed herein. An example switching component may comprise: A switching component comprising: a housing; a carrier body disposed within the housing; a first pair of contact pads disposed on a first surface of the carrier body; and a second pair of contact pads disposed on a second surface of the carrier body, wherein each pair of contact pads is configured to independently make contact with adjacent bridge contact pads in order to actuate an electrical bridge in response to movement of the carrier body.

Abstract: The present invention relates to an anti-CD40 antibody or an antigen-binding fragment thereof that specifically recognizes human, cynomolgus monkey and mouse CD40 molecules and weakly agonizes the CD40 molecules, and an immunoconjugate, a pharmaceutical composition and a combined product containing the anti-CD40 antibody or the antigen-binding fragment thereof. The present invention also relates to a nucleic acid encoding the anti-CD40 antibody or the antigen-binding fragment thereof, a host cell containing the nucleic acid, and a method for preparing the anti-CD40 antibody or the antigen-binding fragment thereof. The present invention further relates to the use of the anti-CD40 antibody or the antigen-binding fragment thereof in the prevention or treatment of tumors or infectious diseases in a subject.

Abstract: Methods, apparatuses and systems for providing a switching component are disclosed herein. An example switching component may comprise: A switching component comprising: a housing; a carrier body disposed within the housing; a first pair of contact pads disposed on a first surface of the carrier body; and a second pair of contact pads disposed on a second surface of the carrier body, wherein each pair of contact pads is configured to independently make contact with adjacent bridge contact pads in order to actuate an electrical bridge in response to movement of the carrier body.

Abstract: An anti-MASP-2 antibody and use thereof. The anti-MASP-2 antibody specifically binds to a human MASP-2 protein at a KD value of about 2E-09M or less, and the anti-MASP-2 antibody specifically binds to a cynomolgus monkey MASP-2 protein at a KD value of about 2E-09M or less. Disclosed are an immunoconjugate containing the anti-MASP-2 antibody, a method for preparing the anti-MASP-2 antibody, and use of the anti-MASP-2 antibody.

Abstract: The present invention provides a preparation of a Siglec-15 binding protein and the use thereof, and specifically relates to an isolated antigen-binding protein, which comprises HCDR3. Provided is the use of the antigen-binding protein in the prevention and treatment of diseases.

Abstract: Provided is an GARP protein antibody, and a cell comprising or expressing the GA RP protein antibody. The GARP protein antibody binds to human GARP/human TGF-?1 complex with a KD value of about 1.0E-12 or less. Also provided are a pharmaceutical combination comprising the GARP protein antibody and an immune checkpoint inhibitor and use thereof.

Abstract: Disclosed are a method of inspecting a printing quality of a 3D printing object using a femtosecond laser beam during a 3D printing process, and an apparatus and a 3D printing system for the same. A laser beam is irradiated from a femtosecond laser source disposed coaxially with a 3D printing laser source to inspect a state of the printing object. The laser beam generated by the femtosecond laser source is separated into a pump laser beam and a probe laser beam. The printing laser beam irradiated from a 3D printing laser source or the pump laser beam is irradiated onto a printing object to generate ultrasonic waves. To measure the ultrasonic waves, a probe laser beam is irradiated onto the printing object. The probe laser beam reflected by the printing object is detected. The quality of the printing object is inspected by analyzing the reflected probe laser beam.

Abstract: Disclosed are a femtosecond laser-based ultrasonic measuring apparatus for a 3D printing process, and a 3D printing system including the apparatus. The apparatus includes a femtosecond laser source for generating a femtosecond laser beam irradiated to inspect a state of a printing object formed by melting a base material by a printing laser beam irradiated from the laser source for 3D printing, a beam splitter for separating the femtosecond laser beam generated by the femtosecond laser source into a pump laser beam and a probe laser beam, an electric/acoustic optical modulator for modulating the pump laser beam, a time delay unit for delaying the probe laser beam, a photo detector for detecting the probe laser beam reflected by the printing object, and a lock-in amplifier for detect an amplitude and a phase of the output signal from the photo detector. The femtosecond laser source is disposed coaxially with a laser source for 3D printing.

Abstract: An example photoionization detector is provided. The example photoionization detector includes an insulation spacer component and a signal collection electrode component disposed on the first surface of the insulation spacer component. In some examples, the signal collection electrode component includes a first electrode layer and a second electrode layer.

Abstract: The present application relates to an antigen-binding protein comprising amino acid mutations compared with the light and heavy chain variable region sequences of omalizumab. The antigen-binding protein of the present application is an anti-IgE engineered antibody. The present application also relates to pharmaceutical compositions comprising the antigen-binding protein, and methods thereof for alleviation or treatment of diseases associated with abnormal level of IgE.