Patents by Inventor Peipei ZHAO

Peipei ZHAO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for culturing tumor infiltrating lymphocytes
    Patent number: 12110506
    Abstract: A method for culturing tumor infiltrating lymphocytes (TIL), the method comprising co-culturing the expanded TIL with feeder cells after contacting the TIL with a T cell co-stimulatory molecule and/or a T cell growth factor for a period of time. In addition, further provided is a method for preventing and/or treating tumors by means of using the tumor infiltrating lymphocytes of the present application.
    Type: Grant
    Filed: May 18, 2023
    Date of Patent: October 8, 2024
    Assignees: SUZHOU GRIT BIOTECHNOLOGY CO., LTD., SHANGHAI GRIT BIOTECHNOLOGY CO., LTD., ZHUHAI TUOYU BIOTECHNOLOGY CO., LTD., SHENZHEN GRIT BIOTECHNOLOGY CO., LTD.
    Inventors: Yarong Liu, Peipei Zhao
  • PREPARATION METHOD FOR TUMOR INFILTRATING LYMPHOCYTE AND USE THEREOF
    Publication number: 20240043801
    Abstract: Provided are a preparation method for a tumor-infiltrating lymphocyte, and use thereof, particularly relating to a method for culturing a tumor-infiltrating lymphocyte, comprising: subjecting a TIL, which is derived from tumor tissues and not expanded in vitro, to in vitro expansion of at least one stage, and wherein the TIL is contacted with a CD28 agonist in the in vitro expansion of at least one stage. Further provided is a method for preventing and/or treating tumors by using the tumor-infiltrating lymphocyte.
    Type: Application
    Filed: December 23, 2021
    Publication date: February 8, 2024
    Inventors: Yarong LIU, Peipei ZHAO, Zixiao SHI
  • METHOD FOR CULTURING TUMOR INFILTRATING LYMPHOCYTES AND USE THEREOF
    Publication number: 20230303977
    Abstract: A method for culturing tumor infiltrating lymphocytes (TIL), the method comprising co-culturing the expanded TIL with feeder cells after contacting the TIL with a T cell co-stimulatory molecule and/or a T cell growth factor for a period of time. In addition, further provided is a method for preventing and/or treating tumors by means of using the tumor infiltrating lymphocytes of the present application.
    Type: Application
    Filed: May 18, 2023
    Publication date: September 28, 2023
    Inventors: Yarong LIU, Peipei ZHAO
  • TARGETED UBIQUITINATION DEGRADATION BRD4 PROTEIN COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
    Publication number: 20220135589
    Abstract: A compound represented by formula (I) or a tautomer, optical isomer, deuterated substance, oxynitride, solvate, pharmaceutically acceptable salt or prodrug thereof can be used in preparing a pharmaceutical composition. The compound or the pharmaceutical composition can be used in the preparation a drug for the prevention and/or treatment of cancer, tumors, viral infections, depression, neurological disorders, trauma, age-related cataracts, organ transplant rejection or autoimmune diseases.
    Type: Application
    Filed: February 3, 2020
    Publication date: May 5, 2022
    Inventors: Chuanwu ZHAO, Chunhua JIANG, Yan ZHANG, Xuejiao ZHANG, Jinlu YANG, Jieqiong KANG, Peipei ZHAO