Abstract: An application of ellagic acid and a metabolic derivative urolithin compound thereof in preparation of an immunomodulatory medicine is provided. Classical animal models of autoimmunity and immunoregulation, such as experimental autoimmune encephalomyelitis, neuromyelitis optica mouse model, ulcerative colitis, and skin transplantation, are used as examples to conduct experiments from various aspects and perspectives, such as neurological function scores, histopathological changes of lesions, inflammatory factor expression, and pro-inflammatory cell numbers.

Abstract: System and methods for asynchronous processing within a web page lifecycle, enabling web page developers to integrate asynchronous work within the web page implementation that can store state inside the page and is applied to requests to the particular page. Handlers initiate event-based or task-based asynchronous operations without keeping a dedicated thread while waiting for a response. The thread is returned to a pool of available threads upon initiation of the process. Results are received on other threads and provided to the page before rendering. Timeout errors are also provided, if a particular result is not received within specified period. The events are delivered in a serial manner so that the page developer uses request instance data without explicit synchronization. This makes a high-scale, asynchronous processing model less complex and more accessible to developers accustomed to web scripting, which is traditionally synchronous.

Abstract: System and methods for asynchronous processing within a web page lifecycle, enabling web page developers to integrate asynchronous work within the web page implementation that can store state inside the page and is applied to requests to the particular page. Handlers initiate event-based or task-based asynchronous operations without keeping a dedicated thread while waiting for a response. The thread is returned to a pool of available threads upon initiation of the process. Results are received on other threads and provided to the page before rendering. Timeout errors are also provided, if a particular result is not received within specified period. The events are delivered in a serial manner so that the page developer uses request instance data without explicit synchronization. This makes a high-scale, asynchronous processing model less complex and more accessible to developers accustomed to web scripting, which is traditionally synchronous.

Abstract: Systems and methods for mitigating cross-site scripting attacks. When an HTTP request is received from a user computer, the HTTP request is evaluated to determine if it includes a script construct. Particularly, data derived from an outside source that is included in the HTTP request is examined for the presence of script constructs. The presence of a script construct indicates that a cross-site scripting attack is being executed and the server computer is able to prevent the attack from being carried out.