Abstract: A novel method to predict toxicity and dose-dependent effects of an agent based on transcriptomic data analysis, by determining a predictive toxicogenomics space (PTGS) score. The PTGS score helps to predict and model the toxicity of compounds typically consisting of chemicals, pharmaceuticals, cosmetics and agrochemicals. The invention further comprises methods of deriving the PTGS score, as well as computer programs to calculate PTGS scores.

Abstract: A novel method to predict toxicity and dose-dependent effects of an agent based on transcriptomic data analysis, by determining a predictive toxicogenomics space (PTGS) score. The PTGS score helps to predict and model the toxicity of compounds typically consisting of chemicals, pharmaceuticals, cosmetics and agrochemicals. The invention further comprises methods of deriving the PTGS score, as well as computer programs to calculate PTGS scores.

Abstract: A method of allocating data transmission resources in a packet-switched telecommunications system which comprises a terminal and a fixed network to which an operational entity is defined for defining resources for a radio bearer. Radio bearer resources are defined for the terminal on the basis of an application used on the radio bearer, and the used compression method of header fields in data packets is selected before the radio bearer resources are defined, the resources being defined in such a manner that they also comprise the capacity required by the selected compression method of header fields in data packets. The compression methods of header fields in data packets, which are supported by the terminal, are transmitted to the operational entity in the fixed network for defining the compression method to be used. Capacity is defined for the radio bearer in two directions, if the selected compression method of header fields in data packets requires a bi-directional connection.

Abstract: The invention relates to a method and a network element for determining cell-based values of a parameter of a selected active uplink transport channel multiplexed with other transport channels to a dedicated physical channel. It is proposed that a value for the parameter of the selected uplink transport channel is computed in predetermined periods of time based on the value of at least one available parameter associated to the dedicated physical channel. Further it is determined for the predetermined periods of time for each of the transport channels whether it is active in the respective period of time. Those periods of time for which it was determined that any other than the selected transport channel was active are excluded from supplying a relevant value for the parameter of the selected active uplink transport channel. The invention equally relates to a corresponding communications network and a corresponding communications system.

Abstract: Common channel resources can be controlled in the uplink of a communication system. The control of the common channel resources can be dependent upon the quality requirements associated with a radio access for use on the up-link common channel relative to a predetermined quality threshold.

Abstract: A method of changing connection parameters in a cellular radio system comprising terminals, base stations, and radio network controllers, and where at least one terminal is in a macrodiversity connection wherein at least one diversity branch goes between the serving radio network controller and the terminal through the drift radio network controller and the drift base station, and which further comprises a load control wherein the radio network controller monitors and balances the use of radio resources in the base stations that operate under it, and a call control wherein the serving radio network controller sets and changes the connection parameters of its connections, and being characterized in that it comprises observing that the load control of the drift radio network controller demands a change in the connection parameters of the terminal communicating through the base station that operates under it, and controlling the serving radio network controller to change the connection parameters of said termina

Abstract: The invention is directed to a method for management of bearers in cellular telecommunication systems in such a situation, when the demand of services is greater than the capacity of the network to provide such services. According to the invention, a set of priority values is associated with each bearer. Preferably, the set of priority values comprises an absolute priority value, which is the same for all bearers associated with a certain USIM, and a relative priority value, which defines the priority order of the bearers associated with a certain USIM. The network uses these priority values to determine, which bearer is dropped, when not enough resources are available.

Abstract: A method of communications in a cellular telecommunications network is disclosed. A cell update message is sent from a user equipment to a network node. The cell update message comprises a cell update cause. The cell update cause includes one of information indicating user data transmission or information indicating control data transmission, if the cause of the cell update is a uplink data transmission. A first procedure is used for data transmission if said information is user data transmission. A different second procedure is used for data transmission if said information is control data transmission.

Abstract: A method and a network element for determining cell-based values of a parameter of a selected active uplink transport channel multiplexed with other transport channels to a dedicated physical channel. It is proposed that a value for the parameter of the selected uplink transport channel is computed in predetermined periods of time based on the value of at least one available parameter associated to the dedicated physical channel. Further it is determined for the predetermined periods of time for each of the transport channels whether it is active in the respective period of time. Those periods of time for which it was determined that any other than the selected transport channel was active are excluded from supplying a relevant value for the parameter of the selected active uplink transport channel.

Abstract: A method of allocating data transmission resources in a packet-switched telecommunications system which comprises a terminal and a fixed network to which an operational entity is defined for defining resources for a radio bearer. Radio bearer resources are defined for the terminal on the basis of an application used on the radio bearer, and the used compression method of header fields in data packets is selected before the radio bearer resources are defined, the resources being defined in such a manner that they also comprise the capacity required by the selected compression method of header fields in data packets. The compression methods of header fields in data packets, which are supported by the terminal, are transmitted to the operational entity in the fixed network for defining the compression method to be used. Capacity is defined for the radio bearer in two directions, if the selected compression method of header fields in data packets requires a bi-directional connection.