Patents by Inventor Peljin Zhang

Peljin Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pulsing of Bile Compartments in Sandwich-Cultured Hepatocytes
    Publication number: 20100035293
    Abstract: A method of pulsing cultured hepatocytes, such as sandwich-cultured hepatocytes. The method includes providing a culture of hepatocytes, the culture having at least one bile canaliculus; exposing the culture of hepatocytes to a calcium-free buffer, whereby the contents of the at least one bile canaliculus are released; and removing the calcium-free buffer Pulsing cultured hepatocytes can reduce cholestasis arid can provide an in vitro culture of hepatocytes the more closely reflects in vivo hepatocyte characteristics.
    Type: Application
    Filed: June 8, 2007
    Publication date: February 11, 2010
    Inventors: Kim Brouwer, Xianbin Tian, Peljin Zhang, Keith Hoffmaster