Patents by Inventor Pen Lai

Pen Lai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11898061
    Abstract: A modified conductive structure includes a conductive substrate and a polymer film disposed over a surface of the polymer film. A chemical bond exists between the polymer film and the conductive substrate, and the polymer film includes repeating units as shown below: wherein A is an antifouling molecule group; B is a sulfur-containing group or a nitrogen-containing group; R is a single bond or a first linking group; C is -L-E, wherein L is a second linking group, E is an enzyme unit; x and z are each independently 0 or an integer from 1 to 10000, and y is an integer from 1 to 10000; o is 0 or an integer from 1 to 50, and when o is an integer from 1 to 50, m and n are each independently 0 or an integer from 1 to 50.
    Type: Grant
    Filed: October 21, 2019
    Date of Patent: February 13, 2024
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Hsin-Chieh Lin, Chih Chang, Chin Pen Lai, Wang-Chin Cheng
  • Publication number: 20230416362
    Abstract: Antibodies and antigen-binding fragments that bind to TIGIT are disclosed. The disclosure further relates to methods and compositions for use in treating an immune-related disease (e.g., a cancer or an infection or infectious disease) by administering a composition disclosed herein.
    Type: Application
    Filed: May 17, 2023
    Publication date: December 28, 2023
    Applicant: Industrial Technology Research Institute
    Inventors: Min-Yuan CHOU, Li-Tsen LIN, Chung-Yuan SUN, Ya-Ping LAI, Chin-Pen LAI, Ssu-Yuan WU, Mei-Wei LIN
  • Patent number: 11667709
    Abstract: Antibodies and antigen-binding fragments that bind to TIGIT are disclosed. The disclosure further relates to methods and compositions for use in treating an immune-related disease (e.g., a cancer or an infection or infectious disease) by administering a composition disclosed herein.
    Type: Grant
    Filed: September 23, 2020
    Date of Patent: June 6, 2023
    Assignee: Industrial Technology Research Institute
    Inventors: Min-Yuan Chou, Li-Tsen Lin, Chung-Yuan Sun, Ya-Ping Lai, Chin-Pen Lai, Ssu-Yuan Wu, Mei-Wei Lin
  • Publication number: 20210087266
    Abstract: Antibodies and antigen-binding fragments that bind to TIGIT are disclosed. The disclosure further relates to methods and compositions for use in treating an immune-related disease (e.g., a cancer or an infection or infectious disease) by administering a composition disclosed herein.
    Type: Application
    Filed: September 23, 2020
    Publication date: March 25, 2021
    Applicant: Industrial Technology Research Institute
    Inventors: Min-Yuan CHOU, Li-Tsen LIN, Chung-Yuan SUN, Ya-Ping LAI, Chin-Pen LAI, Ssu-Yuan WU, Mei-Wei LIN
  • Publication number: 20200157360
    Abstract: A modified conductive structure includes a conductive substrate and a polymer film disposed over a surface of the polymer film. A chemical bond exists between the polymer film and the conductive substrate, and the polymer film includes repeating units as shown below: wherein A is an antifouling molecule group; B is a sulfur-containing group or a nitrogen-containing group; R is a single bond or a first linking group; C is -L-E, wherein L is a second linking group, E is an enzyme unit; x and z are each independently 0 or an integer from 1 to 10000, and y is an integer from 1 to 10000; o is 0 or an integer from 1 to 50, and when o is an integer from 1 to 50, m and n are each independently 0 or an integer from 1 to 50.
    Type: Application
    Filed: October 21, 2019
    Publication date: May 21, 2020
    Applicant: Industrial Technology Research Institute
    Inventors: Hsin-Chieh LIN, Chih CHANG, Chin Pen LAI, Wang-Chin CHENG
  • Publication number: 20180142214
    Abstract: An in vitro method for screening a testing compound to evaluate its potential as a liver drug of the disclosure is provided. The method includes applying the testing compound to cells of an isolated human liver tumor cell line, named as ITRI-H28, measuring a cell viability of the cells and determining the effect of the testing compound on the cells by calculating a half maximal inhibitory concentration (IC50) of the testing compound.
    Type: Application
    Filed: January 3, 2018
    Publication date: May 24, 2018
    Applicant: Industrial Technology Research Institute
    Inventors: Mei-Wei Lin, Dian-Kun Li, Ling-Mei Wang, Ching-Huai Ko, Chin-Pen Lai, Chun-Min Liu, Hsiang-Wen Tseng
  • Publication number: 20180143181
    Abstract: An in vitro method for screening a testing compound to evaluate its potential as a liver drug is provided. The method includes applying the testing compound to cells of an isolated human liver tumor cell line, named as ITRI-H16, measuring a cell viability of the cells and determining the effect of the testing compound on the cells by calculating a half maximal inhibitory concentration (IC50) of the testing compound.
    Type: Application
    Filed: January 3, 2018
    Publication date: May 24, 2018
    Applicant: Industrial Technology Research Institute
    Inventors: Mei-Wei Lin, Dian-Kun Li, Ling-Mei Wang, Ching-Huai Ko, Chin-Pen Lai, Chun-Chung Wang, Hsiang-Wen Tseng
  • Publication number: 20150160195
    Abstract: An isolated human liver tumor cell line is provided and is named as ITRI-H16, and which was deposited in the Food Industry Research and Development Institute with the accession number BCRC960432 on Nov. 7, 2011. A method of an agent screening is also provided. The method includes providing the isolated human liver tumor cell line ITRI-H16 and treating an interest compound to the ITRI-H16 cell line to determine an effect of the interesting compound on the ITRI-H16 cell line.
    Type: Application
    Filed: October 13, 2014
    Publication date: June 11, 2015
    Inventors: Mei-Wei Lin, Dian-Kun Li, Ling-Mei Wang, Ching-Huai Ko, Chin-Pen Lai, Chun-Chung Wang, Hsiang-Wen Tseng
  • Publication number: 20150159141
    Abstract: An isolated human liver tumor cell line is provided, which was named as ITRI-H28 and deposited in the Food Industry Research and Development Institute with the accession number BCRC960457 on Dec. 14, 2012. A method of an agent screening is also provided. The method includes providing the isolated human liver tumor cell line ITRI-H28 and adding an interest compound into the ITRI-H28 cell line to determine an effect on the ITRI-H28 cell line.
    Type: Application
    Filed: October 9, 2014
    Publication date: June 11, 2015
    Inventors: Mei-Wei Lin, Dian-Kun Li, Ling-Mei Wang, Ching-Huai Ko, Chin-Pen Lai, Chun-Min Liu, Hsiang-Wen Tseng
  • Publication number: 20050051472
    Abstract: An artificial kidney (dialyzer) reprocessing system for washing used artificial kidneys includes a high-pressure water supply system providing RO water and chemical solutions for washing and sterilization so as to make artificial kidney (dialyzers) be reused. The feature of the device is that an ozone water device is connected to an high-pressure water supply system in parallel for providing the artificial kidney (dialyzer) reprocessing device ozone water for washing and sterilization. The problem of chemical residuals in the system can also be avoided.
    Type: Application
    Filed: September 10, 2003
    Publication date: March 10, 2005
    Inventors: Willie Chionh, Foo Jin, Pen Lai, Weng Lee
  • Patent number: 6342837
    Abstract: This utility model provides an object identification structure applicable for authentication, production control, and data retrieval, and such structure comprising an object with a printed page to be identified; and its feature is that there is a Radio Frequency Identification Integrated Circuit RFIDIC deposed at the appropriate position on the front printed page, and said RFIDIC further comprising a storage device for storing user's (or storing account) identification code, password, serial number and the like, working with a computer terminal connected to a set of wireless code reader interfaced with RS232 or RS485 for detection. Such arrangement can improve the control of the manufacturing procedure and attain the identification purpose.
    Type: Grant
    Filed: July 20, 2000
    Date of Patent: January 29, 2002
    Inventors: Chun Pen Lai, Paul Y. Liau