Patents by Inventor Penelope E Roberts

Penelope E Roberts has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • B7-H3L cell surface antigen and antibodies that bind thereto
    Patent number: 9574007
    Abstract: The invention provides the identification and characterization of disease and cancer-associated antigen, RAAG10. The invention also provides a family of monoclonal antibodies that bind to antigen RAAG10, methods of diagnosing and treating various human cancers and diseases that express RAAG10.
    Type: Grant
    Filed: June 3, 2014
    Date of Patent: February 21, 2017
    Assignee: MacroGenics, Inc.
    Inventors: Jennie P. Mather, Ronghao Li, Zhuangyu Pan, Penelope E. Roberts
  • Novel B7-H3L Cell Surface Antigen and Antibodies That Bind Thereto
    Publication number: 20140328857
    Abstract: The invention provides the identification and characterization of disease and cancer-associated antigen, RAAG10. The invention also provides a family of monoclonal antibodies that bind to antigen RAAG10, methods of diagnosing and treating various human cancers and diseases that express RAAG10.
    Type: Application
    Filed: June 3, 2014
    Publication date: November 6, 2014
    Applicant: MACROGENICS WEST, INC.
    Inventors: Jennie P. Mather, Ronghao Li, Zhuangyu Pan, Penelope E. Roberts
  • B7-H3L cell surface antigen and antibodies that bind thereto
    Patent number: 8779098
    Abstract: The invention provides the identification and characterization of disease and cancer-associated antigen, RAAG10. The invention also provides a family of monoclonal antibodies that bind to antigen RAAG10, methods of diagnosing and treating various human cancers and diseases that express RAAG10.
    Type: Grant
    Filed: March 27, 2009
    Date of Patent: July 15, 2014
    Assignee: MacroGenics West, Inc.
    Inventors: Jennie P. Mather, Ronghao Li, Zhuangyu Pan, Penelope E. Roberts
  • Human cancer stem cells
    Patent number: 8309354
    Abstract: This invention discloses isolated populations of human cancer stem cells. Methods for characterizing, isolating and culturing human cancer stem cells are also disclosed. Uses for human cancer stem cells are provided.
    Type: Grant
    Filed: January 22, 2008
    Date of Patent: November 13, 2012
    Assignee: MacroGenics West, Inc.
    Inventors: Jennie P. Mather, Penelope E. Roberts
  • Antibodies to oncostatin M receptor
    Patent number: 8216578
    Abstract: The invention provides characterization of the disease and cancer-associated antigen, OSM-R.beta. The invention also provides modulators of OSM-R.beta, including a family of monoclonal antibodies that bind to antigen OSM-R.beta, and methods of diagnosing and treating various human cancers and diseases associated with OSM-R.beta.
    Type: Grant
    Filed: July 2, 2009
    Date of Patent: July 10, 2012
    Assignee: MacroGenics, Inc.
    Inventors: Jennie P. Mather, Penelope E. Roberts
  • Transferrin receptor antibodies
    Patent number: 8187594
    Abstract: The invention provides further characterization of the disease and cancer-associated antigen, transferrin receptor. The invention also provides a novel family of antibodies that bind to the transferrin receptor, methods of diagnosing and treating various human cancers and diseases that express transferrin receptor.
    Type: Grant
    Filed: June 12, 2009
    Date of Patent: May 29, 2012
    Assignee: MacroGenics, Inc.
    Inventors: Jennie P. Mather, Penelope E. Roberts, Ronghao Li
  • Antibodies that bind to EphA2 and methods of use thereof
    Patent number: 8183357
    Abstract: Provided herein is disclosure about the development and characterization of an antibody that binds to antigen EphA2 which is present on a variety of human cancers from breast, lung, prostate, and colons. Methods of diagnosing and treating various cancers by using such antibodies directed against this antigen are also disclosed.
    Type: Grant
    Filed: November 30, 2009
    Date of Patent: May 22, 2012
    Assignee: MacroGenics, Inc.
    Inventors: Jennie P. Mather, Penelope E. Roberts
  • LUCA2 and Antibodies That Bind Thereto
    Publication number: 20110045006
    Abstract: The invention provides the identification and characterization of disease and cancer-associated antigen, LUCA2. The invention also provides a family of monoclonal antibodies that bind to antigen LUCA2, methods of diagnosing and treating various human cancers and diseases that express LUCA2.
    Type: Application
    Filed: October 29, 2010
    Publication date: February 24, 2011
    Applicant: MacroGenics West, Inc.
    Inventors: Jennie P. Mather, Penelope E. Roberts
  • LUCA2 and antibodies that bind thereto
    Patent number: 7847070
    Abstract: The invention provides the identification and characterization of disease and cancer-associated antigen, LUCA2. The invention also provides a family of monoclonal antibodies that bind to antigen LUCA2, methods of diagnosing and treating various human cancers and diseases that express LUCA2.
    Type: Grant
    Filed: January 31, 2006
    Date of Patent: December 7, 2010
    Assignee: Raven biotechnologies, inc.
    Inventors: Jennie P. Mather, Penelope E. Roberts
  • Antibodies that bind to EphA2 and methods of use thereof
    Patent number: 7776328
    Abstract: Provided herein is disclosure about the development and characterization of an antibody that binds to antigen EphA2 which is present on a variety of human cancers from breast, lung, prostate, and colons. Methods of diagnosing and treating various cancers by using such antibodies directed against this antigen are also disclosed.
    Type: Grant
    Filed: June 30, 2009
    Date of Patent: August 17, 2010
    Assignee: MacroGenics, Inc.
    Inventors: Jennie P. Mather, Penelope E. Roberts
  • TRANSFERRIN RECEPTOR ANTIBODIES
    Publication number: 20100166745
    Abstract: The invention provides further characterization of the disease and cancer-associated antigen, transferrin receptor. The invention also provides a novel family of antibodies that bind to the transferrin receptor, methods of diagnosing and treating various human cancers and diseases that express transferrin receptor.
    Type: Application
    Filed: June 12, 2009
    Publication date: July 1, 2010
    Inventors: Jennie P. MATHER, Penelope E. Roberts, Ronghao Li
  • Antibodies That Bind to EphA2 and Methods of Use Thereof
    Publication number: 20100086969
    Abstract: Provided herein is disclosure about the development and characterization of an antibody that binds to antigen EphA2 which is present on a variety of human cancers from breast, lung, prostate, and colons. Methods of diagnosing and treating various cancers by using such antibodies directed against this antigen are also disclosed.
    Type: Application
    Filed: November 30, 2009
    Publication date: April 8, 2010
    Applicant: MACROGENICS, INC.
    Inventors: Jennie P. Mather, Penelope E. Roberts
  • ANTIBODIES TO ONCOSTATIN M RECEPTOR
    Publication number: 20090269340
    Abstract: The invention provides characterization of the disease and cancer-associated antigen, OSM-R.beta. The invention also provides modulators of OSM-R.beta, including a family of monoclonal antibodies that bind to antigen OSM-R.beta, and methods of diagnosing and treating various human cancers and diseases associated with OSM-R.beta.
    Type: Application
    Filed: July 2, 2009
    Publication date: October 29, 2009
    Inventors: Jennie P. MATHER, Penelope E. Roberts
  • ANTIBODIES THAT BIND TO EPHA2 AND METHODS OF USE THEREOF
    Publication number: 20090263391
    Abstract: Provided herein is disclosure about the development and characterization of an antibody that binds to antigen EphA2 which is present on a variety of human cancers from breast, lung, prostate, and colons. Methods of diagnosing and treating various cancers by using such antibodies directed against this antigen are also disclosed.
    Type: Application
    Filed: June 30, 2009
    Publication date: October 22, 2009
    Inventors: Jennie P. MATHER, Penelope E. Roberts
  • NOVEL RAAG10 CELL SURFACE TARGET AND A FAMILY OF ANTIBODIES RECOGNIZING THAT TARGET
    Publication number: 20090202561
    Abstract: The invention provides the identification and characterization of disease and cancer-associated antigen, RAAG10. The invention also provides a family of monoclonal antibodies that bind to antigen RAAG10, methods of diagnosing and treating various human cancers and diseases that express RAAG10.
    Type: Application
    Filed: March 27, 2009
    Publication date: August 13, 2009
    Inventors: Jennie P. MATHER, Ronghao Li, Zhuangyu Pan, Penelope E. Roberts
  • Antibodies to oncostatin M receptor
    Patent number: 7572896
    Abstract: The invention provides characterization of the disease and cancer-associated antigen, OSM-R.beta. The invention also provides modulators of OSM-R.beta, including a family of monoclonal antibodies that bind to antigen OSM-R.beta, and methods of diagnosing and treating various human cancers and diseases associated with OSM-R.beta.
    Type: Grant
    Filed: February 3, 2006
    Date of Patent: August 11, 2009
    Assignee: Raven biotechnologies, Inc.
    Inventors: Jennie P. Mather, Penelope E. Roberts
  • Transferrin receptor antibodies
    Patent number: 7572895
    Abstract: The invention provides further characterization of the disease and cancer-associated antigen, transferrin receptor. The invention also provides a novel family of antibodies that bind to the transferrin receptor, methods of diagnosing and treating various human cancers and diseases that express transferrin receptor.
    Type: Grant
    Filed: June 7, 2005
    Date of Patent: August 11, 2009
    Assignee: Raven Biotechnologies, Inc.
    Inventors: Jennie P. Mather, Penelope E. Roberts, Ronghao Li
  • Antibodies that bind to EphA2 and methods of use thereof
    Patent number: 7569672
    Abstract: Provided herein is disclosure about the development and characterization of an antibody that binds to antigen EphA2 which is present on a variety of human cancers from breast, lung, prostate, and colons. Methods of diagnosing and treating various cancers by using such antibodies directed against this antigen are also disclosed.
    Type: Grant
    Filed: February 6, 2006
    Date of Patent: August 4, 2009
    Assignee: Raven biotechnologies, inc.
    Inventors: Jennie P. Mather, Penelope E. Roberts
  • RAAG10 cell surface target and a family of antibodies recognizing that target
    Patent number: 7527969
    Abstract: The invention provides the identification and characterization of disease and cancer-associated antigen, RAAG10. The invention also provides a family of monoclonal antibodies that bind to antigen RAAG10, methods of diagnosing and treating various human cancers and diseases that express RAAG10.
    Type: Grant
    Filed: June 19, 2003
    Date of Patent: May 5, 2009
    Assignee: Raven biotechnologies, inc.
    Inventors: Jennie P. Mather, Ronghao Li, Zhuangyu Pan, Penelope E. Roberts
  • Human pancreatic epithelial progenitor cells and methods of isolation and use thereof
    Patent number: 7078231
    Abstract: The invention discloses a substantially pure population of human pancreatic progenitor cells and methods of isolating and culturing the pancreatic progenitor cells. By carefully manipulating the microenvironment of the pancreatic progenitor cells, multiple passages are attainable wherein the pancreatic progenitor cells do not senesce and furthermore, are capable of becoming functional exocrine or endocrine cells. In addition, several methods of use of human pancreatic progenitor cells are disclosed herein.
    Type: Grant
    Filed: April 9, 2002
    Date of Patent: July 18, 2006
    Assignee: Raven biothechnologies, inc.
    Inventors: Penelope E Roberts, Jennie Powell Mather