Patents by Inventor Penelope Jane Huggins

Penelope Jane Huggins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Acyl hydrazone derivative compounds for treating disease
    Patent number: 11603364
    Abstract: The present invention relates to compounds that have zinc and/or iron ionophore activity and their use in treating diseases that are modulated by reducing zinc and/or iron.
    Type: Grant
    Filed: August 27, 2021
    Date of Patent: March 14, 2023
    Assignee: Alterity Therapeutics Limited
    Inventors: Silas Bond, Penelope Jane Huggins, Jack Gordon Parsons
  • COMPOUNDS FOR AND METHODS OF TREATING DISEASES
    Publication number: 20220064142
    Abstract: The present invention relates to compounds that have zinc and/or iron ionophore activity and their use in treating diseases that are modulated by reducing zinc and/or iron.
    Type: Application
    Filed: August 27, 2021
    Publication date: March 3, 2022
    Inventors: Silas BOND, Penelope Jane HUGGINS, Jack Gordon PARSONS
  • Compounds for and methods of treating diseases
    Patent number: 11155547
    Abstract: The present invention provides heterocyclic compounds of formula (I) that modulate biological metals and to pharmaceutical compositions containing such compounds. The invention particularly relates to compounds that modulate iron and to compounds for the treatment of diseases, particularly neurological diseases such as Parkinson's disease (PD), Alzheimer's disease (AD), Alzheimer-type dementia, Huntington's disease (HD), amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and multiple system atrophy (MSA).
    Type: Grant
    Filed: April 23, 2021
    Date of Patent: October 26, 2021
    Assignee: Alterity Therapeutics Limited
    Inventors: Silas Bond, Penelope Jane Huggins, Jack Gordon Parsons
  • 4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE COMPOUNDS
    Publication number: 20210230159
    Abstract: The present invention relates to compounds of the formula I or II: (I) (II) processes for their preparation and their use as pharmaceutical agents or compositions in the treatment, of neurological disorders.
    Type: Application
    Filed: April 7, 2021
    Publication date: July 29, 2021
    Applicant: Prana Biotechnology Limited
    Inventors: Penelope Jane Huggins, Jack Gordon Parsons, Kevin Jeffrey Barnham, Elisabeth Colette Louise Gautier, Antony Vincent Robinson
  • 4H-pyrido[1,2-a]pyrimidin-4-one compounds
    Patent number: 11008319
    Abstract: The present invention relates to compounds of the formula I or II: (I) (II) processes for their preparation and their use as pharmaceutical agents or compositions in the treatment, of neurological disorders.
    Type: Grant
    Filed: June 24, 2020
    Date of Patent: May 18, 2021
    Assignee: Prana Biotechnology Limited
    Inventors: Penelope Jane Huggins, Jack Gordon Parsons, Kevin Jeffrey Barnham, Elisabeth Colette Louise Gautier, Antony Vincent Robinson
  • Imidazo [1,5-a]pyridine compounds and their use
    Patent number: 10941143
    Abstract: The present invention provides compounds that modulate biological metals and to pharmaceutical compositions containing such compounds. The invention particularly relates to imidazo[1,5-a]pyridine compounds of formula (I) that modulate iron and are useful for the treatment of diseases, particularly neurological diseases such as Parkinson's disease (PD), Alzheimer's disease (AD), Alzheimer-type dementia, Huntington's disease (HD), amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and multiple system atrophy (MSA). The compounds of formula (I) being where variables are defined herein.
    Type: Grant
    Filed: March 13, 2020
    Date of Patent: March 9, 2021
    Assignee: ALTERITY THERAPEUTICS LIMITED
    Inventors: Silas Bond, Penelope Jane Huggins, Jack Gordon Parsons
  • 4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE COMPOUNDS
    Publication number: 20200317670
    Abstract: The present invention relates to compounds of the formula I or II: (I) (II) processes for their preparation and their use as pharmaceutical agents or compositions in the treatment, of neurological disorders.
    Type: Application
    Filed: June 24, 2020
    Publication date: October 8, 2020
    Applicant: Prana Biotechnology Limited
    Inventors: Penelope Jane Huggins, Jack Gordon Parsons, Kevin Jeffrey Barnham, Elisabeth Colette Louise Gautier, Antony Vincent Robinson
  • COMPOUNDS FOR AND METHODS OF TREATING DISEASES
    Publication number: 20200291021
    Abstract: The present invention provides compounds that modulate biological metals and to pharmaceutical compositions containing such compounds. The invention particularly relates to imidazo[1,5-a]pyridine compounds that modulate iron and are useful for the treatment of diseases, particularly neurological diseases such as Parkinson's disease (PD), Alzheimer's disease (AD), Alzheimer-type dementia, Huntington's disease (HD), amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and multiple system atrophy (MSA).
    Type: Application
    Filed: March 13, 2020
    Publication date: September 17, 2020
    Inventors: Silas BOND, Penelope Jane HUGGINS, Jack Gordon PARSONS
  • 4H-pyrido[1,2-A]pyrimidin-4-one compounds
    Patent number: 10738050
    Abstract: The present invention relates to compounds of the formula I or II: (I) (II) processes for their preparation and their use as pharmaceutical agents or compositions in the treatment, of neurological disorders.
    Type: Grant
    Filed: May 10, 2019
    Date of Patent: August 11, 2020
    Assignee: Prana Biotechnology Limited
    Inventors: Penelope Jane Huggins, Jack Gordon Parsons, Kevin Jeffrey Barnham, Elisabeth Colette Louise Gautier, Antony Vincent Robinson
  • 4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE COMPOUNDS
    Publication number: 20190352301
    Abstract: The present invention relates to compounds of the formula I or II: (I) (II) processes for their preparation and their use as pharmaceutical agents or compositions in the treatment, of neurological disorders.
    Type: Application
    Filed: May 10, 2019
    Publication date: November 21, 2019
    Inventors: Penelope Jane Huggins, Jack Gordon Parsons, Kevin Jeffrey Barnham, Elisabeth Colette Louise Gautier, Antony Vincent Robinson
  • 4H-pyrido[1,2-A]pyrimidin-4-one compounds
    Patent number: 10287285
    Abstract: The present invention relates to compounds of the formula I or II: (I) (II) processes for their preparation and their use as pharmaceutical agents or compositions in the treatment, of neurological disorders.
    Type: Grant
    Filed: December 2, 2015
    Date of Patent: May 14, 2019
    Assignee: Prana Biotechnology Limited
    Inventors: Penelope Jane Huggins, Jack Gordon Parsons, Kevin Jeffrey Barnham, Elisabeth Colette Louise Gautier, Antony Vincent Robinson
  • 4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE COMPOUNDS
    Publication number: 20170267676
    Abstract: The present invention relates to compounds of the formula I or II: (I) (II) processes for their preparation and their use as pharmaceutical agents or compositions in the treatment, of neurological disorders.
    Type: Application
    Filed: December 2, 2015
    Publication date: September 21, 2017
    Inventors: Penelope Jane Huggins, Jack Gordon Parsons, Kevin Jeffrey Barnham, Elisabeth Colette Louise Gautier, Anthony Vincent Robinson
  • QUINAZOLINONE COMPOUNDS
    Publication number: 20150359796
    Abstract: The present invention relates to quinazolinone compounds, processes for their preparation and their use as pharmaceutical agents for the treatment of Parkinson's disease (PD).
    Type: Application
    Filed: August 21, 2015
    Publication date: December 17, 2015
    Applicant: PRANA BIOTECHNOLOGY LIMITED
    Inventors: Penelope Jane Huggins, Jack Gordon Parsons
  • Method of treatment of age-related macular degeneration (AMD)
    Patent number: 9163018
    Abstract: The present invention relates generally to the field of treatment and prophylaxis of retinal degenerative diseases. More particularly, the present invention contemplates a method for preventing, reducing the risk of development of, or otherwise treating or ameliorating the symptoms of, age-related macular degeneration (AMD) or related retinal conditions in mammals and in particular humans. The present invention further provides therapeutic compositions enabling dose-dependent or dose-specific administration of agents useful in the treatment and prophylaxis of age-related macular degeneration or related retinal degenerative conditions.
    Type: Grant
    Filed: November 22, 2013
    Date of Patent: October 20, 2015
    Assignee: PRANA BIOTECHNOLOGY INC.
    Inventors: Penelope Jane Huggins, Gaik Being Kok
  • Quinazolinone compounds
    Patent number: 9145375
    Abstract: The present invention relates to quinazolinone compounds, processes for their preparation and their use as pharmaceutical agents for the treatment of Parkinson's disease (PD). The quinazolinone compounds are of general formula (I).
    Type: Grant
    Filed: October 7, 2014
    Date of Patent: September 29, 2015
    Assignee: PRANA BIOTECHNOLOGY LIMITED
    Inventors: Penelope Jane Huggins, Jack Gordon Parsons
  • QUINAZOLINONE COMPOUNDS
    Publication number: 20150025072
    Abstract: The present invention relates to quinazolinone compounds, processes for their preparation and their use as pharmaceutical agents for the treatment of Parkinson's disease (PD). The quinazolinone compounds are of general formula (I).
    Type: Application
    Filed: October 7, 2014
    Publication date: January 22, 2015
    Applicant: PRANA BIOTECHNOLOGY LIMITED
    Inventors: Penelope Jane HUGGINS, Jack Gordon PARSONS
  • Quinazolinone compounds
    Patent number: 8889695
    Abstract: The present invention relates to quinazolinone compounds, processes for their preparation and their use as pharmaceutical agents for the treatment of Parkinson's disease (PD). The quinazolinone compounds are of general formula (I).
    Type: Grant
    Filed: December 23, 2009
    Date of Patent: November 18, 2014
    Assignee: Prana Biotechnology Limited
    Inventors: Penelope Jane Huggins, Jack Gordon Parsons
  • METHOD OF TREATMENT OF AGE-RELATED MACULAR DEGENERATION (AMD)
    Publication number: 20140088122
    Abstract: The present invention relates generally to the field of treatment and prophylaxis of retinal degenerative diseases. More particularly, the present invention contemplates a method for preventing, reducing the risk of development of, or otherwise treating or ameliorating the symptoms of, age-related macular degeneration (AMD) or related retinal conditions in mammals and in particular humans. The present invention further provides therapeutic compositions enabling dose-dependent or dose-specific administration of agents useful in the treatment and prophylaxis of age-related macular degeneration or related retinal degenerative conditions.
    Type: Application
    Filed: November 22, 2013
    Publication date: March 27, 2014
    Applicant: PRANA BIOTECHNOLOGY LIMITED
    Inventors: Penelope Jane HUGGINS, Gaik Being KOK
  • Use of pyridopyrimidine compounds in the treatment of gliomas
    Patent number: 8163760
    Abstract: The present invention relates generally to therapeutic agents, formulations comprising them and their use in the treatment, amelioration and/or prophylaxis of glioma brain tumors and related conditions. The therapeutic agent comprises two fused 6-membered rings with at least a nitrogen at position 1 and a hydroxyl at position 8.
    Type: Grant
    Filed: June 22, 2007
    Date of Patent: April 24, 2012
    Assignee: Prana Biotechnology Limited
    Inventors: Ashley Bush, Penelope Jane Huggins, Jack Gordon Parsons, Gaik Beng Kok, Vijaya Kenche
  • QUINAZOLINONE COMPOUNDS
    Publication number: 20120040980
    Abstract: The present invention relates to quinazolinone compounds, processes for their preparation and their use as pharmaceutical agents for the treatment of Parkinson's disease (PD). The quinazolinone compounds are of general formula (I).
    Type: Application
    Filed: December 23, 2009
    Publication date: February 16, 2012
    Applicant: PRANA BIOTECHNOLOGY LIMITED
    Inventors: Penelope Jane Huggins, Jack Gordon Parsons