Patents by Inventor Penelope Markham

Penelope Markham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Formulations of terlipressin
    Patent number: 12156898
    Abstract: The disclosure provides pharmaceutical compositions comprising terlipressin having increased concentration with long term storage stability.
    Type: Grant
    Filed: May 22, 2020
    Date of Patent: December 3, 2024
    Assignee: BioVie, Inc.
    Inventors: Penelope Markham, Jonathan Adams, Denise Smith, Jorge Bacardit Cabado
  • Treatment of Ascites
    Publication number: 20240165193
    Abstract: A method for treating ascites patients by administering the peptide drug terlipressin by continuous infusion. The patients include those whose ascites condition has not progressed to hepatorenal syndrome (HRS). Administration may be accomplished with a continuous infusion pump.
    Type: Application
    Filed: January 23, 2024
    Publication date: May 23, 2024
    Inventors: Paolo Angeli, Penelope Markham, Jonathan Adams
  • METHODS OF TREATING DISEASE WITH TERLIPRESSIN
    Publication number: 20230241156
    Abstract: Provided are methods of treating a disease with arginine vasopressin or an analogue thereof that reduce the risk of hyponatremia. Specifically, the invention relates to the novel observation that subjects receiving co-administration of terlipressin and gabapentin or pregabalin have a high incidence of severe hyponatremia.
    Type: Application
    Filed: February 3, 2023
    Publication date: August 3, 2023
    Inventors: Penelope MARKHAM, Joseph M. PALUMBO
  • Treatment of Ascites
    Publication number: 20230146264
    Abstract: A method for treating ascites patients by administering the peptide drug terlipressin by continuous infusion. The patients include those whose ascites condition has not progressed to hepatorenal syndrome (HRS). Administration may be accomplished with a continuous infusion pump.
    Type: Application
    Filed: June 3, 2022
    Publication date: May 11, 2023
    Inventors: Paolo Angeli, Penelope Markham, Jonathan Adams
  • FORMULATIONS OF TERLIPRESSIN
    Publication number: 20220233634
    Abstract: The disclosure provides pharmaceutical compositions comprising terlipressin having increased concentration with long term storage stability.
    Type: Application
    Filed: May 22, 2020
    Publication date: July 28, 2022
    Inventors: Penelope Markham, Jonathan Adams, Denise Smith, Jorge Bacardit Cabado
  • Formulations of Terlipressin
    Publication number: 20220202907
    Abstract: The disclosure provides pharmaceutical compositions comprising terlipressin having increased concentration with long term storage stability.
    Type: Application
    Filed: March 18, 2022
    Publication date: June 30, 2022
    Inventors: Penelope Markham, Jonathan Adams, Denise Smith, Jorge Bacardit Cabado
  • Treatment of ascites
    Patent number: 11364277
    Abstract: A method for treating ascites patients by administering the peptide drug terlipressin by continuous infusion. The patients include those whose ascites condition has not progressed to hepatorenal syndrome (HRS). Administration may be accomplished with a continuous infusion pump.
    Type: Grant
    Filed: April 9, 2019
    Date of Patent: June 21, 2022
    Assignee: BioVie Inc.
    Inventors: Paolo Angeli, Penelope Markham, Jonathan Adams
  • Treatment of Ascites
    Publication number: 20190365848
    Abstract: A method for treating ascites patients by administering the peptide drug terlipressin by continuous infusion. The patients include those whose ascites condition has not progressed to hepatorenal syndrome (HRS). Administration may be accomplished with a continuous infusion pump.
    Type: Application
    Filed: April 9, 2019
    Publication date: December 5, 2019
    Inventors: Paolo Angeli, Penelope Markham, Jonathan Adams
  • Treatment of Ascites
    Publication number: 20180000887
    Abstract: A method for treating ascites patients by administering the peptide drug terlipressin by continuous infusion. The patients include those whose ascites condition has not progressed to hepatorenal syndrome (HRS). Administration may be accomplished with a continuous infusion pump.
    Type: Application
    Filed: April 19, 2017
    Publication date: January 4, 2018
    Inventors: Paolo Angeli, Penelope Markham, Jonathan Adams
  • Treatment of ascites
    Patent number: 9655945
    Abstract: A method for treating ascites patients by administering the peptide drug terlipressin by continuous infusion. The patients include those whose ascites condition has not progressed to hepatorenal syndrome (HRS). Administration may be accomplished with a continuous infusion pump.
    Type: Grant
    Filed: June 30, 2016
    Date of Patent: May 23, 2017
    Assignee: BIOVIE, Inc.
    Inventors: Paolo Angeli, Penelope Markham, Jonathan Adams
  • Treatment of Ascites
    Publication number: 20170000844
    Abstract: A method for treating ascites patients by administering the peptide drug terlipressin by continuous infusion. The patients include those whose ascites condition has not progressed to hepatorenal syndrome (HRS). Administration may be accomplished with a continuous infusion pump.
    Type: Application
    Filed: June 30, 2016
    Publication date: January 5, 2017
    Inventors: Paolo Angeli, Penelope Markham, Jonathan Adams
  • COMPOSITIONS FOR TREATMENT WITH METALLOPEPTIDASES, METHODS OF MAKING AND USING THE SAME
    Publication number: 20110044968
    Abstract: The present invention is directed to biocompatible compositions and the use of metal bridges to connect a back-bone and a metallopeptidase active agent. In certain instances, the subject compositions provide a means of achieving sustained release of the metallopeptidase active agent after administration to a subject.
    Type: Application
    Filed: March 10, 2009
    Publication date: February 24, 2011
    Applicant: Pharmal N Corporation
    Inventors: Elijah M. Bolotin, Gerardo Castillo, Penelope Markham, Manshun Lai
  • Bactericidal antimicrobial methods and compositions for use in treating gram positive infections
    Publication number: 20050043369
    Abstract: The present invention relates generally to the field of bacteriology. More particularly, the present invention provides methods and compositions for increasing the effectiveness of existing antibacterial agents and methods of overcoming bacterial resistance. Specifically, the invention provides methods of enhancing the action of an antibacterial agent by use of an antibiotic potentiator. Compositions of antibiotic potentiators including an acyl hydrazide, an oxy amide, and an 8-hydroxy quinoline also are disclosed.
    Type: Application
    Filed: July 23, 2004
    Publication date: February 24, 2005
    Applicants: Protez Pharmaceuticals Inc., The Board of Trustees of The University of Illinois
    Inventors: Penelope Markham, Debbie Mulhearn, Ekaterina Klyachko, Alexander Neyfakh, David Crich, Mohamed-Rami Jaber, Michael Johnson