Abstract: Provided are an isolated binding protein including an antigen binding domain of cardiac troponin I (cTnI), as well as a preparation and uses of the binding protein. The antigen binding domain includes at least one complementary determining region selected from the amino acid sequences defined herein; or the antigen-binding domain has at least 80% sequence identity with the complementary determining regions of said amino acid sequences and has an affinity for cardiac troponin I of KD?3.33×10?8 mo/L. The binding protein may be used in the field of cTnI protein detection.

Abstract: Provided is an isolated binding protein including an antigen-binding domain that binds to NS1 protein. The isolated binding protein includes specific heavy chain CDRs and light chain CDRs. The binding protein can specifically recognize and bind to NS1, and has relatively high sensitivity and specificity, thereby achieving the detection of dengue virus. Moreover, the binding protein is not required to be produced by inducing hybridoma cells in mouse abdominal cavity, and thus it is simple in production and has more stable antibody function.

Abstract: Provided is an isolated binding protein including an antigen binding domain binding to an NS1 protein, and including specific heavy chain CDR and light chain CDR. The binding protein can specifically identify and bind to NS1, and has relatively high sensitivity and specificity, so as to detect dengue vims. Moreover, the binding protein does not need to be produced by injecting hybridoma cells into mouse peritoneal cavity, while simplifying production, thus stabilizing antibody functionality.

Abstract: Six-membered high-entropy foam for hydrogen production by water splitting and preparation method are provided. The foam consists of Ni, Fe, Cu, Co, Mo, and Pt, comprising 10 at %-25 at % of Ni, 10 at %-25 at % of Fe, 10 at %-25 at % of Cu, 10 at %-25 at % of Co, 10 at %-25 at % of Mo, and 10 at %-25 at % of Pt. Catalyst loading of the foam can reach a range of 0.8 mg/cm2-3.2 mg/cm2, which is much higher than the effective catalyst loading of most nano-catalysts. When used as catalyst for hydrogen production by water splitting, the hydrogen evolution overpotential of the surface of the six-membered high-entropy foam is within a range of 36 mV-60 mV, and the foam operates stably at industrial-level current density (500 mA/cm2). The preparation method does not require harsh environment such as high temperature or high vacuum, making the method simple and easy to implement, with low-cost raw materials.

Abstract: Disclosed is an isolated binding protein including a cardiac troponin I (cTnI) antigen binding domain, and preparation and a use and the like of the binding protein. The antigen binding domain includes at least one complementarity determining region selected from an amino acid sequence defined in this article, or has at least 80% sequence identity with the complementarity determining region of the amino acid sequence and has KD?9.96×10?8 mol/L affinity with cTnI. The binding protein may be used in the detection field of the cTnI protein.

Abstract: The present disclosure relates to the field of medical diagnosis, and specifically, relates to a synthetic peptide for detecting HIV-1. The synthetic peptide is obtained by mutating the amino acid sequence set forth as SEQ ID NO: 1. The synthetic peptide can better detect anti-HIV-1 antibodies, and can better avoid potential “false negative” and “false positive” results.

Abstract: The method for preventing and controlling glacial lake outbreak flood and related debris flows by the present invention is mainly controlling the scale of the floods by separating water and rocks and dispersing its energy step by step. The cascading amplification effects of floods can be reduced by controlling the initiation of source material with energy dissipation by using ground sills, groups of piles, and placed large stones and prefabricated artificial structures. The diversion dam built in the downstream area discharge floods in different layers, which can quickly guide water to the main river. The preconstructed engineering system can be used in a timely manner to prevent and control floods and debris flows induced by a sudden outburst of glacial lakes in areas with important facilities and inhabitants enduring the risk of natural hazards. Prevention and control systems can separate floods and debris flows and dissipate their energy.

Abstract: Provided is an isolated binding protein including an antigen binding domain binding to an NS1 protein, and comprising specific heavy chain CDR and light chain CDR. The binding protein can specifically identify and bind to NS1, and has relatively high sensitivity and specificity, so as to detect dengue virus. Moreover, the binding protein does not need to be produced by injecting hybridoma cells into mouse peritoneal cavity, while simplifying production, thus stabilizing antibody functionality.

Abstract: An antibody against a novel coronavirus, and a reagent and a kit for detecting the novel coronavirus, which relate to the technical field of antibodies. The antibody against the novel coronavirus includes a heavy chain complementarity determinant region and a light chain complementarity determinant region. The antibody has good affinity for N protein of the novel coronavirus, and has good sensitivity and specificity for detecting the novel coronavirus. Antibody options are provided for detection of the novel coronavirus.

Abstract: The present disclosure relates to an HCV recombinant antigen and use of the same. Provided is an HCV recombinant antigen, which includes at least two NS3 antigens, at least one NS4 antigen, and at least one core antigen. Further provided are a nucleic acid encoding the HCV recombinant antigen, an expression vector containing the nucleic acid, a host cell containing the expression vector, a conjugate containing the HCV recombinant antigen, and a kit containing the HCV recombinant antigen, and the like.

Abstract: The application relates to an HCV recombinant antigen and a mutant thereof. The application provides an HCV recombinant antigen, the HCV recombinant antigen including at least 1 NS3 antigen, wherein at least one cysteine of the NS3 antigen in positions 1192-1517 of an HCV amino acid sequence is mutated into G and/or A, and preferably mutated into A. The application further provides a nucleic acid encoding the HCV recombinant antigen, an expression vector including the nucleic acid, a host cell including the expression vector, a conjugate including the HCV recombinant antigen, and a kit including the HCV recombinant antigen.

Abstract: A device for monitoring and identifying a mountain torrent and debris flow and a method for early warning of disasters relate to the technical field of debris flow protection. The device includes a computation device, sensors, an amplifier and an analog-to-digital converter. The sensors convert an acquired impact force signal into a digital signal by the amplifier and the analog-to-digital converter, and transmits the digital signal to the computation device. The computation device utilizes the digital signal to compute an energy coefficient of a liquid impact signal and a solid-liquid impact energy ratio, and a debris flow mode is monitored and identified in combination with a threshold range of the energy coefficient and a threshold range of the solid-liquid impact energy ratio. The device identifies the nature of the mountain torrent and debris flow through time-frequency analysis of an impact force signal generated by the debris flow to sensors.

Abstract: A method for a whole-process numerical simulation and hazard forecast of a mountain disaster is provided. The method includes: S1, a high space-time rainfall forecast of a mountain area; S2, a hydrodynamic process and numerical simulation: establishing a hydrodynamic process model and solving the hydrodynamic process model; S3, a motion model and numerical simulation of a mountain torrent and debris flow disaster; and S4, a risk analysis and hazard forecast of a small watershed disaster. The present invention predicts disaster hazard and dynamically and quantitatively evaluates risk loss according to a whole-process scenario simulation of the disaster driven by a climate forecast result, improves current disaster level forecasts to hazard forecasts, and serves for accurate disaster preventions and accurate rescues.

Abstract: A method for determining male infertility includes detecting abnormal expression of sex-determining gene on X chromosome (SDX) or SDX protein using a test kit.

Abstract: The method for preventing and controlling glacial lake outbreak flood and related debris flows by the present invention is mainly controlling the scale of the floods by separating water and rocks and dispersing its energy step by step. The cascading amplification effects of floods can be reduced by controlling the initiation of source material with energy dissipation by using ground sills, groups of piles, and placed large stones and prefabricated artificial structures. The diversion dam built in the downstream area discharge floods in different layers, which can quickly guide water to the main river. The preconstructed engineering system can be used in a timely manner to prevent and control floods and debris flows induced by a sudden outburst of glacial lakes in areas with important facilities and inhabitants enduring the risk of natural hazards. Prevention and control systems can separate floods and debris flows and dissipate their energy.

Abstract: A semiconductor device and fabricating method thereof is disclosed. The method comprises depositing epitaxial layers over a silicon substrate to form a semiconductor layer surface; forming at least one mesa portion on the semiconductor layer surface; depositing a metal stack on the semiconductor layer surface; subjecting the semiconductor layer surface to a rapid thermal annealing system for a two-step ohmic contact annealing in H2/N2 forming gas (FG) and then nitrogen; subjecting the semiconductor layer surface to an oxygen plasma treatment; and depositing a T-shaped metal gate on the semiconductor layer surface. A semiconductor device comprises a semiconductor layer surface having an epitaxial layer disposed over a silicon substrate; at least one mesa portion formed on the semiconductor layer surface; a metal stack, disposed on the semiconductor layer surface, and sequentially annealed in FG and nitrogen; and a T-shaped metal gate on the semiconductor layer surface.

Abstract: A device for monitoring and identifying a mountain torrent and debris flow and a method for early warning of disasters relate to the technical field of debris flow protection. The device includes a computation device, sensors, an amplifier and an analog-to-digital converter. The sensors convert an acquired impact force signal into a digital signal by the amplifier and the analog-to-digital converter, and transmits the digital signal to the computation device. The computation device utilizes the digital signal to compute an energy coefficient of a liquid impact signal and a solid-liquid impact energy ratio, and a debris flow mode is monitored and identified in combination with a threshold range of the energy coefficient and a threshold range of the solid-liquid impact energy ratio. The device identifies the nature of the mountain torrent and debris flow through time-frequency analysis of an impact force signal generated by the debris flow to sensors.

Abstract: Embodiments of the present disclosure are directed to methods, systems, devices and kits corresponding to a method for analyzing charge variants of a protein such as vascular endothelial growth factor VEGF-Trap.

Abstract: An electrochromic energy storage device disclosed herein comprises a first electrode and a second electrode disposed in an electrolyte, wherein the first electrode comprises a coordination polymer, wherein the coordination polymer comprises a transition metal and a tetradentate ligand conjugated to the transition metal, wherein the transition metal and the tetradentate ligand render the first electrode operable to (i) store electrical energy and at the same time change its optical state upon electrical charging of the electrochromic energy storage device, and (ii) release electrical energy stored therein and at the same time change its optical state upon electrical discharge of the electrochromic energy storage device. A method of forming the electrochromic energy storage device and a method of forming an electrochromic energy storage film are disclosed herein.

Abstract: A method and system for code package. A dataset is generated according to a code package. The code package includes an image file associated with a container for a tenant. The dataset includes general information related to security aspects of the image file. The image file includes two or more image layers. Generating the dataset according to the code package includes: exporting an image layer from the image file; and obtaining a configuration file of the exported image layer as the dataset. In response to the vulnerability having been identified, the image file is updated with a patch that fixes the identified vulnerability. The patch includes a new image layer added to the two or more image layers in the updated image file.