Abstract: The present invention provides compounds of Formula I, pharmaceutical compositions comprising these compounds and methods of using these compounds to prevent or treat FXR-mediated or TGR5-mediated diseases or conditions.

Abstract: A detection device includes a frame, a transport mechanism, detection mechanisms, and a grasping mechanism. The transport mechanism includes a feeding line, a first flow line, and a second flow line arranged in parallel on the frame. The detection mechanisms are arranged on the frame and located on two sides of the transport mechanism. The grasping mechanism is arranged on the frame and used to transport workpieces on the feeding line to the detection mechanisms, transport qualified workpieces to the first flow line, and transport unqualified workpieces to the second flow line.

Abstract: The present invention provides compounds represented by Formula I, or pharmaceutically acceptable salts, stereoisomers, solvates, hydrates or combination thereof, The invention also provides pharmaceutical compositions comprising these compounds and methods of using this compounds for treating FXR-mediated or TGR5-mediated diseases or conditions.

Abstract: An indication to remove one or more data in a time series database is received. A metadata index associated with the time series database is updated to indicate a soft removal of each data of the one or more data. A data hole index associated with the time series database is updated to indicate a data hole at a location of each data of the one or more data in the time series database. Responsive to an input/output rate for the time series database being below a threshold, the data hole of each data of the one or more data is optimized.

Abstract: An elongate fuel element is described that has a silicon carbide cladding enclosing a fuel, such as UO2, wherein the fuel is dimensioned relative to the cladding to define gaps at each lateral end of the enclosure sufficiently large such that upon swelling in use, the fuel does not increase the strain on the cladding beyond the limits of the claddings strain tolerance. The lateral gaps at the ends of the fuel allow lateral expansion during swelling that reduces the strain on the cladding.

Abstract: A method includes starting a second virtual machine using a first virtualization emulator of a later version when a first virtual machine is running based on a second virtualization emulator of an earlier version, where the second virtual machine has a same configuration as the first virtual machine, suspending the first virtual machine and the second virtual machine, sending device status information of the first virtual machine to the second virtual machine, and controlling the second virtual machine to resume running based on the device status information.

Abstract: Online virtual machine migration methods, systems and apparatus are disclosed for migrating a source virtual machine running on a source server to a destination server. In an implementation, a method includes: the source server sends dirty memory page address information and device state information of a source virtual machine to a first offloading card inserted in the source server through a first internal channel, and the first internal channel is disposed between the first offloading card and the source server. The first offloading card reads a dirty memory page from a memory of the source server according to the dirty memory page address information, and sends the dirty memory page, the dirty memory page address information, and the device state information to a second offloading card of the destination server.

Abstract: A method includes starting a second virtual machine using a first virtualization emulator of a later version when a first virtual machine is running based on a second virtualization emulator of an earlier version, where the second virtual machine has a same configuration as the first virtual machine, suspending the first virtual machine and the second virtual machine, sending device status information of the first virtual machine to the second virtual machine, and controlling the second virtual machine to resume running based on the device status information.