Abstract: A N-heterocyclic five-membered ring-containing capsid protein assembly inhibitor, and a pharmaceutical composition and use thereof, specifically relating to a compound as represented by formula I, a stereoisomer, a tautomer, a geometrical isomer, a solvate, an active metabolite, a hydrate, a prodrug or a pharmaceutically acceptable salt thereof, a pharmaceutical composition thereof, and a medical use thereof. The medical use comprises the use in treating diseases benefiting from the capsid protein assembly inhibitor, and in particular, diseases caused by hepatitis B virus infection.

Abstract: Provided are a chromium-free passivated and film-covered tinned plate, a passivation treatment solution for manufacturing a passivation film, and a manufacturing method for a tinned plate. The chromium-free passivated and film-covered tinned plate comprises a tinned plate and a polyester film laminated on a surface of the tinned plate. The tinned plate comprises a substrate, a tin coating and a passivation film covering a surface of the tin coating. The passivation film does not contain chromium, and contains 2.0-20 mg/m2 of zinc and 10-60 mg/m2 of silicon. A solvent in the passivation treatment solution is water, and the solution contains 0.5-5.0 wt % of a zinc salt and 10-30 wt % of an organosiloxane or a polysiloxane.

Abstract: The present invention relates to a low-temperature dry preparation method for a flame-retardant fabric, for use in compounding a first substrate with a second substrate, wherein the first substrate and the second substrate are pressed together by means of hot melt adhesive-based cold compounding: spraying and coating a surface of the first substrate with a hot metal adhesive in a flowable state, feeding the first substrate and the second substrate together into a press roller group, making the hot melt adhesive on the surface of the first substrate face the second substrate, and cold pressing the first substrate, the hot melt adhesive, and the second substrate together by means of the press roller group.

Abstract: The present disclosure provides a display panel and a display device. The display panel includes: a substrate; a plurality of display units arranged on a side of the substrate, each of the plurality of display units including at least one sub-pixel; a plurality of elastic stretching units arranged on a side of the substrate, each of the plurality of elastic stretching units being connected between two adjacent display units, and a plurality of hollow regions being formed between the plurality of elastic stretching units and the plurality of display units. A sum of areas of the plurality of hollow regions is a, a sum of areas of the plurality of display units is b, and a sum of areas of the plurality of elastic stretching units is c; 15%?a/(a+b+c)×100%?30%.

Abstract: The present disclosure relates to a system and a method. The system may include a magnetic resonance imaging (MRI) apparatus configured to acquire MRI data with respect to a region of interest (ROI) and a therapeutic apparatus configured to apply therapeutic radiation to at least one portion of the ROI. The MRI apparatus may include a plurality of main magnetic coils arranged coaxially along an axis, a plurality of shielding magnetic coils arranged coaxially along the axis, and a cryostat in which the plurality of main magnetic coils and the plurality of shielding magnetic coils are arranged.

Abstract: The present disclosure relates to a system for radiation therapy. The system may include a magnetic resonance imaging (MRI) apparatus and a radiation therapy apparatus. The MRI apparatus may be configured to acquire magnetic resonance imaging data with respect to a region of interest (ROI). The radiation therapy apparatus may be configured to apply therapeutic radiation to at least one portion of the ROI when rotating with a gantry. The radiation therapy apparatus may include an eddy current reduction apparatus coupled to the gantry. The eddy current reduction apparatus may include at least one structure, wherein each of the at least one structure may include a plurality of internal structures and at least some of the plurality of internal structures are electrically disconnected from each other.

Abstract: An electronic device is provided. The electronic device includes a housing, an infrared transmitter, a light guide member, and a decorative sheet. The infrared transmitter and the light guide member are both disposed in the housing. The housing is provided with a through hole, and at least a part of the light guide member is disposed in the through hole. The light guide member has a first end and a second end that are opposite to each other. The first end has a curved surface protruding opposite to the second end. The infrared transmitter is opposite to a light inlet surface, and the infrared transmitter emits infrared light toward the light inlet surface. The second end has a light outlet surface. At least a part of the infrared light incident in the light guide member through the light inlet surface emits on the light outlet surface.

Abstract: An electronic device is provided. The electronic device includes a housing, an infrared transmitter, a light guide member, and a decorative sheet. The infrared transmitter and the light guide member are both disposed in the housing. The housing is provided with a through hole, and at least a part of the light guide member is disposed in the through hole. The light guide member has a first end and a second end that are opposite to each other. The first end has a curved surface protruding opposite to the second end. The infrared transmitter is opposite to a light inlet surface, and the infrared transmitter emits infrared light toward the light inlet surface. The second end has a light outlet surface. At least a part of the infrared light incident in the light guide member through the light inlet surface emits on the light outlet surface.

Abstract: Provided are a method for preparing an mRNA-LNP and use thereof, on which a technology platform of an uncapped-linear mRNA with unmodified uridine is based. The provided linear mRNA is composed of a 5? UTR including the IRES, a coding region and a poly A region has a simple structure and high stability and efficiency on its expression in vivo and in vitro. The uncapped-linear mRNA with unmodified uridine is then encapluslated by a new lipid nanoparticle (LNP-1) to form an mRNA-LNP.

Abstract: Methods, systems, and computer-readable storage media for receiving, by a service mesh provisioned within a container orchestration system, a request from a client, determining, by the service mesh, a load balancing strategy that is to be applied for routing of the request within the heterogeneous cluster, and transmitting, by the service mesh, the request to a service within the heterogenous cluster, the service routing the request to a node for processing based on the load balancing strategy.

Abstract: Methods, systems, and computer-readable storage media for executing, within the container orchestration system, the application using one or more resource units, each resource unit including an application container and an ancillary container, the ancillary container executing a set of GPU metric exporters, receiving, from the application and for each resource unit, a GPU metric including a GPU utilization associated with a respective resource unit, determining, for each resource unit, a custom GPU metric based on a respective GPU metric, the custom GPU metric aggregating values of the respective GPU metric over a time period, determining, by an autoscaler, an average GPU metric based on one or more custom GPU metrics, and selectively scaling, by the autoscaler, the application within the container orchestration system based on the average GPU metric by adjusting a number of resource units executing the application.

Abstract: The disclosure discloses an optoelectronic element comprising: an optoelectronic unit comprising a first metal layer, a second metal layer, and an outermost lateral surface; an insulating layer having a first portion overlapping the optoelectronic unit and extending beyond the lateral surface, and a second portion separated from the first portion in a cross-sectional view; and a first conductive layer formed on the insulating layer.

Abstract: Methods, systems, and computer-readable storage media for receiving data representative of time-based snapshots of a time-evolving graph, the data including vertices and edges for each time-based snapshot, for each source vertex in a time-based snapshot: executing a static single-source-shortest-path (SSSP) algorithm to provide a set of distance labels, each distance label including data representative of a distance between the source vertex and a reachable vertex within the time-based snapshot, and determining a total number of reachable vertices from the source vertex within the time-based snapshot and a total distance between the source vertex and the reachable vertices based on the set of distance labels within the time-based snapshot, and providing, for each source vertex, a set of closeness centrality values, each closeness centrality value corresponding to a respective time-based snapshot.

Abstract: The disclosure discloses an optoelectronic element comprising: an optoelectronic unit comprising a first metal layer, a second metal layer, and an outermost lateral surface; an insulating layer having a first portion overlapping the optoelectronic unit and extending beyond the lateral surface, and a second portion separated from the first portion in a cross-sectional view; and a first conductive layer formed on the insulating layer.

Abstract: The disclosure discloses an optoelectronic element comprising: an optoelectronic unit comprising a first metal layer, a second metal layer, and an outermost lateral surface; an insulating layer having a first portion overlapping the optoelectronic unit and extending beyond the lateral surface, and a second portion separated from the first portion in a cross-sectional view; and a first conductive layer formed on the insulating layer.

Abstract: An optoelectronic element includes an optoelectronic unit, a first metal layer, a second metal layer, a conductive layer and a transparent structure. The optoelectronic unit has a central line in a top view, a top surface, and a bottom surface. The second metal layer is formed on the top surface, and has an extension portion crossing over the central line and extending to the first metal layer. The conductive layer covers the first metal layer and the extension portion. The transparent structure covers the bottom surface without covering the top surface.

Abstract: Methods, systems, and computer-readable storage media for receiving data representative of the temporal graph, the data representing vertices, edges between vertices, and temporal features, determining a set of earliest-arrival dependencies, each earliest arrival dependency including an earliest feasible edge between vertices from a list of edges of the temporal graph, providing data representative of an edge-scan-dependency graph (ESD-graph) based on the data representative of the temporal graph, and the set of earliest-arrival dependencies, the ESD-graph including vertices representing edges of the temporal graph, and edges representing earliest-arrival dependencies between vertices, providing data representative of a level-assigned ESD-graph including a level assigned to each vertex of the ESD-graph, and determining earliest-arrival times between a source vertex, and each vertex of the temporal graph by executing a parallel edge scan of the level-assigned ESD-graph.

Abstract: This disclosure discloses a light-emitting device. The light-emitting device has a first outermost sidewall and includes a light-emitting diode and an electrode. The light-emitting diode has a pad and a side surface. The electrode has a segment formed on the pad to extend beyond the side surface, and a first protrusion extending from the segment to the first outermost sidewall.

Abstract: Methods, systems, and computer-readable storage media for receiving data representative of the temporal graph, the data representing vertices, edges between vertices, and temporal features, determining a set of earliest-arrival dependencies, each earliest arrival dependency including an earliest feasible edge between vertices from a list of edges of the temporal graph, providing data representative of an edge-scan-dependency graph (ESD-graph) based on the data representative of the temporal graph, and the set of earliest-arrival dependencies, the ESD-graph including vertices representing edges of the temporal graph, and edges representing earliest-arrival dependencies between vertices, providing data representative of a level-assigned ESD-graph including a level assigned to each vertex of the ESD-graph, and determining earliest-arrival times between a source vertex, and each vertex of the temporal graph by executing a parallel edge scan of the level-assigned ESD-graph.

Abstract: An insert for connecting to a receiving structure having at least two parallel members includes having a first end and a second end opposite to the first end; a first spline disposed at the first end of the cylinder, wherein the first spline is arranged circumferentially on an outer surface of the cylinder; and an interlocking clinch disposed at the second end of the cylinder and circumferentially around the cylinder; wherein the first spline and the interlocking clinch are respectively fastened to two parallel members of the structure, and at least one of the first and second ends of the cylinder is fastened to a fitting member through a connecting member. The first spline can be fitted to one member of the structure with interference, and the interlocking clinch is self-fastened with another member of the structure due to material flow.