Abstract: An antibody monomer, including an antibody, and a first DNA monomer or a second DNA monomer, where the antibody is an anti-vascular cell adhesion molecule 1 (antiVCAM1) antibody. Nucleotide sequences of the first and second DNA monomers respectively consist of SEQ ID NO:1 and SEQ ID NO:2. A kit including the antibody monomer and an initiator including a nucleotide sequence consisting of SEQ ID NO: 3 is provided. This application also provides a polyvalent antibody including a first antibody monomer and a second antibody monomer, where the first antibody monomer includes the first DNA monomer and the antiVCAM1 antibody, and the second antibody monomer includes the second DNA monomer and the antiVCAM1 antibody. This application further provides a mesenchymal stem cell modified with the antibody monomer or the polyvalent antibody, and an application thereof in the treatment of tissue damage.

Abstract: A method for mining an entity relationship, apparatus, electronic device, and a storage medium are provided. An implementation of the method may include: searching, in a query statement set, for a query statement satisfying a preset condition corresponding to a target entity word; in response to at least one query statement satisfying the preset condition corresponding to the target entity word being found in the query statement set, mining an associated entity word corresponding to the target entity word based on the found at least one query statement satisfying the preset condition corresponding to the target entity word.

Abstract: This application discloses an inverter circuit for an inverter such as a photovoltaic inverter. Also disclosed are inverters and photovoltaic power systems including such inverter circuits. The inverter circuit is based on a HERIC topology, and in the inverter circuit a third capacitor and a fourth capacitor are bridge-connected between a bus and a first longitudinal bridge and between the bus and a second longitudinal bridge respectively. In this way, when the inverter circuit goes from a starting phase to a freewheeling phase, the third capacitor and the fourth capacitor can stabilize a voltage fluctuation caused by different turn-off speeds of the switching transistors in the HERIC topology, to prevent resonance caused by the voltage fluctuations.

Abstract: The present invention relates to a method for preparing a ?-lactam derivative, wherein a substituted N-quinoline-3-butenamide derivative is used as a substrate to react with a toluene derivative or a heterocyclic derivative at 90-150° C. in the presence of DTBP and a copper salt catalyst, to prepare a ?-lactam derivative. According to the method of the present invention, a variety of ?-lactam derivatives can be obtained with a high yield. The reaction of the present invention has mild reaction conditions, and simple reaction operation and post-treatment process, and is suitable for large-scale production.

Abstract: A multi-layered regenerator for adjusting temperature of gas or fluid flowing therethrough is provided. The regenerator includes a cover portion and a base portion, each of the cover portion and the base portion comprising a plurality of apertures permitting gas or fluid to flow from a top to a bottom of the multi-layered regenerator, and from the bottom to the top of the multi-layered regenerator. At least one of the cover portion and the base portion include thermal layers stacked vertically with respect to one another, each of the plurality of thermal layers having a predetermined porosity. At least a first one of the plurality of thermal layers is formed of a thermally conductive material and a second one of the plurality of thermal layers is formed of a thermally insulative material.

Abstract: The present invention provides a platform for large-scale profiling of post-transcriptional molecular targets including microRNAs (miRNAs) and methylated messenger RNAs (such as m6A mRNAs) with subcellular spatial resolution in a tissue-wide scale. The present platform is capable of high-throughput isolation of intracellular molecules by contacting an array of functionalized nanoprobes with a target tissue sample for capturing the molecular targets, and the isolated molecular targets are in-situ analysed. The present invention also provides a spectrum barcoding system and related method for digitally quantifying the isolated molecular targets on the nanoprobes and mapping with an imprint of the tissue sample to provide a single-cell spatial coordinate and expression pattern of each of the molecular targets corresponding to different sub-regions of the tissue sample.

Abstract: The present invention provides an electricity-driven, micro-electroporation based drug delivery system, in particular, an electrically conductive array of microprotrusions containing intended substances or molecules to be delivered, which is to the benefit of a recipient receiving vaccination transcutaneously in the absence of any assistive mechanical or actuation means as in conventional injection methods, so as to lower safety risks, improve immunization efficiency, and also induce immune response of the recipient more effectively at a relatively lower dose of vaccines.

Abstract: A paste extruding device for a tubular positive plate includes a plate main body. The plate main body includes a cross beam, ribs and a tab. The ribs are linearly distributed on a bottom surface of the cross beam, and the tab is provide on a top surface of the cross beam. A processing tube is sleeved outside the rib, and the processing tube has a cavity shell structure with an open top. A filling cavity is formed between the rib and the processing tube, and a sliding groove is provided at a vertical central line of an outer wall of the processing tube. A processing sliding base is slidably sleeved on the outer wall of the processing tube. A paste extruding cavity is provided at an inner top of the processing sliding base, and a cooling cavity is provided at an inner bottom of the processing sliding base.

Abstract: Disclosed herein are methods of detecting viruses and methods of making a diagnosis of viral infection, by using RNA and DNA probes. According to some embodiments of the present disclosure, the method is useful in detecting and diagnosing SARS-CoV-2 infection. Accordingly, also disclosed herein are a kit for detecting SARS-CoV-2.

Abstract: A paste extruding device for a tubular positive plate includes a plate main body. The plate main body includes a cross beam, ribs and a tab. The ribs are linearly distributed on a bottom surface of the cross beam, and the tab is provide on a top surface of the cross beam. A processing tube is sleeved outside the rib, and the processing tube has a cavity shell structure with an open top. A filling cavity is formed between the rib and the processing tube, and a sliding groove is provided at a vertical central line of an outer wall of the processing tube. A processing sliding base is slidably sleeved on the outer wall of the processing tube. A paste extruding cavity is provided at an inner top of the processing sliding base, and a cooling cavity is provided at an inner bottom of the processing sliding base.

Abstract: The present application provides a full hydraulic synchronous steering system for a low-speed heavy-load vehicle, where the system includes: a steering control mechanism and a steering actuator; by determining a desired steering curve between a steering wheel angle and a rear wheel angle, when a steering error exceeds an allowable error, a controller controls the opening and closing of an oil replenishment solenoid valve (5) and an oil discharge solenoid valve (4) to adjust a flow rate of the oil flowing into a steering cylinder (7), so as to ensure that the steering error is within an allowable error range, thereby implementing synchronous steering. A method for manipulating the full hydraulic synchronous steering system is further provided. The full hydraulic synchronous steering system and the method can improve synchronous steering capability of the low-speed heavy-load vehicle and change a steering ratio, thereby improving safety and direction feeling of a driver.

Abstract: The present invention provides methods for signal amplification. The methods use DNA hybridization chain reaction to build labeled nanoscaffolds off of target analytes. The methods are reversible, as the detectable signal can be removed using DNA hybridization and hydrolysis.

Abstract: A method of determining one or more target nucleic acids in cells includes the steps of: delivering one or more probes into the cells, each of the one or more probes being capable of binding with corresponding target nucleic acid present in the cells to form a double-stranded sequence; inserting an array of functionalized nanoneedles into the cells to bind with the double-stranded sequence; and hybridizing the bound double-stranded sequence with a first and second DNA sequence to produce a hybridized product, the first and second DNA sequence being at least partially complementary to each other. A kit for determining a target nucleic acid in cells includes a first reagent comprising a probe for binding with the target nucleic acid to form a double-stranded sequence; and an array of functionalized nanoneedles comprising a protein for binding with the double-stranded sequence.

Abstract: The present disclosure provides a method and apparatus for determining an extended reading content, a device, and a storage medium, relating to the field of data processing. The method may include: displaying a target page, in response to a viewing request to the target page; giving a reading prompt to an extended reading resource in the target page, based on a corresponding relationship between a requirement recognition result of at least one target reading content in the target page and the extended reading resource; and displaying the extended reading resource, in response to the viewing request matching the reading prompt.

Abstract: A method for analyzing neuropharmacology of a drug, including the steps of providing a set of brain activity maps representing changes of a brain activity of a living species under an influence of a plurality of known drugs each consisting of a known chemical structure; clustering the set of brain activity maps to form a plurality of functional classifiers; and classifying a brain activity map associated with a chemical compound using the functional classifiers so as to predict a neuropharmacology of the chemical compound.

Abstract: The present invention relates generally to methods of generating a biomimetic cell wall (BCW) on a target surface, compositions comprising the BCW, and methods of use of the compositions, including biomedical applications of the BCW coated compositions.

Abstract: The invention discloses a retrieval method and device for judgment documents and relates to the technical field of data retrieval, mainly aiming to mark existing judgment documents with information codes and perform vertical and horizontal retrieval according to the association relation among the information codes during retrieval so as to provide more comprehensive retrieval results.

Abstract: This application discloses an inverter circuit for an inverter such as a photovoltaic inverter. Also disclosed are inverters and photovoltaic power systems including such inverter circuits. The inverter circuit is based on a HERIC topology, and in the inverter circuit a third capacitor and a fourth capacitor are bridge-connected between a bus and a first longitudinal bridge and between the bus and a second longitudinal bridge respectively. In this way, when the inverter circuit goes from a starting phase to a freewheeling phase, the third capacitor and the fourth capacitor can stabilize a voltage fluctuation caused by different turn-off speeds of the switching transistors in the HERIC topology, to prevent resonance caused by the voltage fluctuations.

Abstract: A computer-implemented method according to one embodiment includes receiving, by a protocol server, a source code file. The source code file includes a TCDF. The TCDF includes parameters for a test case, preparation steps related to the test case, and a plurality of test case blocks. Each test case block of the plurality of test case blocks includes a set of testing steps and a certificate. The source code file is output by the protocol server to a SUT with an instruction for the SUT to execute the source code file in order to implement the set of testing steps for each of the plurality of test case blocks. A plurality of responses are received by the protocol server from the SUT. Each of the responses are compared against the certificates of the test case blocks. A test result is generated by the protocol server based on the comparisons.