Abstract: Provided in the present invention are an anti-CD73 antibody and the use thereof. Specifically, a heavy chain variable region of the antibody contains HCDR1 to HCDR3 having amino acid sequences as shown in SEQ ID NOs: 15-17, respectively. Furthermore, a light chain variable region of the antibody contains LCDR1 to LCDR3 having amino acid sequences as shown in SEQ ID NOs: 18-20, respectively.

Abstract: An example turbine fracturing apparatus and an example turbine fracturing well site are disclosed. The turbine fracturing apparatus may include a turbine engine, configured to provide power; a deceleration device, having an input end and a plurality of output ends, the input end being connected with the turbine engine; a plurality of plunger pumps, connected with the plurality of output ends, respectively, each of the plurality of plunger pumps being configured to intake low-pressure fluid and discharge high-pressure fluid; and an auxiliary power unit, configured to provide auxiliary power to at least one of the turbine engine, the deceleration device, or each of the plurality of plunger pumps. The auxiliary power unit, the turbine engine, and the deceleration device may be sequentially arranged.

Abstract: Provided are an anti-CD73-anti-PD-1 bispecific antibody, a pharmaceutical composition thereof and a use thereof.

Abstract: A virtual-machine cold migration method, an electronic device and a storage medium, which relate to the field of artificial intelligence, such as cloud computing, distributed storage, or the like. The method may include: selecting a node as a target physical machine from nodes of a cluster where a to-be-migrated virtual machine is located, the target physical machine and a source physical machine where the virtual machine is located being different nodes; and migrating, by means of point-to-point data transmission, system disk data and data disk data in the virtual machine from the source physical machine to the target physical machine to obtain a migrated virtual machine, and deleting the virtual machine on the source physical machine.

Abstract: A combustion-gas supply system and a combustion-gas supply method thereof, a device equipped with a turbine engine, and a fracturing system are provided. The combustion-gas supply system includes a main pipeline and a multi-functional pipeline; the main pipeline includes a first sub-pipeline and a second sub-pipeline; the first sub-pipeline includes a first gas intake pipe, a first gas supply valve and a first gas outlet pipe arranged in sequence; the second sub-pipeline includes a combustion-gas supply valve and a gas supply pipe, the first gas outlet pipe is connected with the combustion-gas supply valve, the gas supply pipe is configured to be connected with a turbine engine, the multi-functional pipeline includes a second gas intake pipe, a second gas supply valve and a second gas outlet pipe arranged in sequence, and the second gas outlet pipe is communicated with the first gas outlet pipe.

Abstract: An intelligent integrated anti-collision system and method for a pier, including: a radar sensing device disposed at the joint between the pier and a girder, image collection devices disposed around the pier, control system, hydraulic system and execution device, where the radar sensing and image collection devices transmit collected signals to the control system, which uses the hydraulic system to control the action of the execution device; the execution device is disposed at a middle part of the pier and includes a plurality of sections of steel-reinforced rubber concrete girder connected end to end through pulleys, the hydraulic system can drive the pulleys to rotate to enable the sections to be located on the same horizontal line, and an energy dissipation apparatus is disposed at the tail end of the last section to realize energy dissipation of the energy generated by impact when an object impacts the energy dissipation apparatus.

Abstract: A sealed pressured horizontal directional drilling continuous coring device for engineering geological investigation includes an outer tube assembly and an inner tube assembly matching the outer tube assembly. The outer tube assembly includes a single-wall drill pipe and a dual-wall drill pipe assembly. The inner wall of the dual-wall drill pipe assembly is sequentially provided with a bullet stop head, a bullet room, a suspended seat ring, a positioning inner lock, a positioning outer lock, a first centralizing ring, a lock ring seat and a drill from top to bottom. The inner tube assembly includes a spear head, a first sealing component, a bullet positioning mechanism, a recovery pipe, a second sealing component, an in-place reporting mechanism, a core blockage alarm mechanism, a single-action mechanism, a guiding mechanism, a buffer mechanism, an adjustment mechanism, a core tube and a core clamping mechanism.

Abstract: The invention provides an antibody that can bind IGF-1R. The antibody is composed of light chain and heavy chain. The light chain and heavy chain variable regions are one of the combinations of SEQ ID NO:2 and SEQ ID NO:3, SEQ ID NO:4 and SEQ ID NO:5, SEQ ID NO:6 and SEQ ID NO:7, SEQ ID NO:8 and SEQ ID NO:9, SEQ ID NO:10 and SEQ ID NO:11, SEQ ID NO:12 and SEQ ID No 13, SEQ ID NO:14 and SEQ ID NO:15. The invention also provides nucleic acid molecules encoding the antibody binding IGF-1R, vectors containing the nucleic acid, cells transformed by the vectors, and uses of these nucleic acids, vectors, and cells.

Abstract: A touch display panel has a first region and a second region. The touch display panel includes a first touch unit located in the first region, and a plurality of second touch units located in the second region, wherein the plurality of second touch units is arranged in a matrix in a first direction and a second direction, the first direction intersecting the second direction. An area of an orthographic projection of the first touch unit on a plane of the touch display panel is smaller than an area of an orthographic projection of one second touch unit of the plurality of second touch units on the plane of the touch display panel. An absolute value of a difference between an impedance of the first touch unit and an impedance of the one second touch unit is smaller than a first preset threshold.

Abstract: Free-standing non-fouling polymers and polymeric compositions, monomers and macromonomers for making the polymers and polymeric compositions, objects made from the polymers and polymeric compositions, and methods for making and using the polymers and polymeric compositions

Abstract: A computer-implemented method includes: obtaining, by a computing device, data from sensors that collect the data in a system during a time, wherein the data is multi-dimensional time series data; creating, by the computing device, matrices based on the data; determining, by the computing device using a first computer-based numerical modeling method, patterns based on the matrices; creating, by the computing device using a second computer-based numerical modeling method, a single time series model based on the patterns; and predicting, by the computing device, a future condition of the system using the time series model with current data of the system.

Abstract: Identifying node importance in a machine learning pipeline is provided. Changes in accuracy of the machine learning pipeline are recorded for each respective node setting change in a randomly generated group of node settings inputted into each corresponding node included in the machine learning pipeline. A regression model is generated to determine a relationship between each respective node setting change in the randomly generated group of node settings inputted into each corresponding node and the changes in the accuracy of the machine learning pipeline. A node of importance is identified in the machine learning pipeline using the regression model based on the relationship between each respective node setting change in the randomly generated group of node settings inputted into each corresponding node and the changes in the accuracy of the machine learning pipeline.

Abstract: The present disclosure is directed to a system for fracturing operation in oil/gas fields. The disclosed fracturing system is integrated onto a semitrailer that can be conveniently transported to any oil field. The disclosed fracturing system further includes major components needed for delivering high-pressure fracturing fluid into a wellhead, including but not limited to at least one power generation source and at least one plunger pump driven by the at least one power generation source via simple transmission mechanisms utilizing reduction gearbox and/or transmission shafts. The power generation source, in particular, includes a turbine engine capable of being powered by 100% natural gasified liquid fuel.

Abstract: An operation method of a turbine fracturing device and a turbine fracturing device are provided. The turbine fracturing device includes a turbine engine, a speed reducer, a brake mechanism, and a fracturing pump, the method includes: driving, by the turbine engine, the fracturing pump to perform a fracturing operation through the speed reducer so as to keep the fracturing pump in an operating state, the fracturing pump being configured to suck fluid of a first pressure and discharge fluid of a second pressure, the second pressure being greater than the first pressure; and in response to an idling instruction, the turbine engine entering an idling state and triggering a brake operation so as to keep the fracturing pump in a non-operating state.

Abstract: The present disclosure discloses a transmission device of a hybrid vehicle. The transmission device includes an input shaft assembly, a power generation motor input shaft assembly, a driving motor input shaft assembly, an output shaft assembly, a clutch, an accelerating planetary gear train, a decelerating planetary gear train, and a parking mechanism. The input shaft assembly is located at a front end of the transmission device. The power generation motor input shaft assembly is located between the accelerating planetary gear train and the driving motor input shaft assembly. The driving motor input shaft assembly is located between the power generation motor input shaft assembly and the decelerating planetary gear train. The output shaft assembly is located at a tail end of the transmission device. The clutch is located between a power generation motor and a driving motor.

Abstract: Methods and systems for provable, auditable and secure software updates for resource-constrained IoT devices are provided via a security framework and a protocol for owner-controlled software updates for IoT devices through blockchain.

Abstract: Example resource determining methods, indication methods, and apparatus are described. On example method includes receiving a downlink data channel by a terminal from a network device. The terminal determines a first uplink control channel resource from a plurality of uplink control channel resources based on an index of the last symbol for the downlink data channel and a time for processing the downlink data channel by the terminal. The terminal sends acknowledgment information to the network device on the first uplink control channel resource, where the acknowledgment information is used to determine a reception status of the downlink data channel.

Abstract: A touch panel includes first touch-electrodes and second touch-electrodes, and a bezel region includes first wires and second wires. Each of the first wires is electrically connected a respective one of the first touch-electrodes in a one-to-one correspondence through a respective first connection end, and each of the second wires is electrically connected a respective one of the second touch-electrodes in a one-to-one correspondence through a respective second connection end. First connection ends of at least two adjacent first sub-touch-electrodes located at a central position of the touch region in the second direction are located at a same side of the touch region in the first direction, and/or second connection ends of at least two adjacent second sub-touch-electrodes located at a central position of the touch region in the first direction are located at a same side of the touch region in the second direction.

Abstract: Provided are a crystal of a tricyclic compound as shown in formula (I) or a pharmaceutically acceptable salt thereof and a preparation method therefor, and the use thereof in preparing a drug for treating PDE3- and/or PDE4-related diseases.

Abstract: A fracturing device, a firefighting method thereof, and a computer readable storage medium are disclosed. The fracturing device includes a power unit, the power unit includes a muffling compartment, a turbine engine, and a firefighting system; the firefighting system includes a firefighting material generator, at least one firefighting sprayer and at least one firefighting detector, the at least one firefighting sprayer and the at least one firefighting detector are located in the muffling compartment, each of the at least one firefighting sprayer is connected with the firefighting material generator and configured to spray out firefighting material generated by the firefighting material generator.